Invention Application
- Patent Title: AGENT, USES AND METHODS FOR TREATMENT
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Application No.: US15743549Application Date: 2016-07-12
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Publication No.: US20180305455A1Publication Date: 2018-10-25
- Inventor: Lars Christian Biilmann Rønn , Ibrahim John Malik , Jeffrey b. Stavenhagen , Søren Christensen , Jan Egebjerg , Arnout Gerritsen , Edward Van Den Brink , Paul Parren , Rob De Jong
- Applicant: H. Lundbeck A/S
- Priority: GB1512215.3 20150713
- International Application: PCT/EP2016/066516 WO 20160712
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61P25/28

Abstract:
The present invention relates to monoclonal anti-Sortilin antibodies which have been found useful in correcting a deficient level of progranulin (PGRN). In particular, these antibodies can be used in the treatment of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).
Public/Granted literature
- US10479835B2 Agent, uses and methods for treatment Public/Granted day:2019-11-19
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