公开(公告)号：USRE46816E1

公开(公告)日：2018-05-01

申请号：US14228173

申请日：2014-03-27

Applicant: Genentech, Inc.

Inventor： Daryl T. Baldwin ,  Sarah C. Bodary-Winter ,  Andrew C. Chan ,  Hilary Clark ,  Janet K. Jackman ,  William I. Wood

IPC: G01N33/53 ,  C07K16/18 ,  C07K14/47 ,  C12Q1/68 ,  A61K39/00

CPC classification number: C07K16/18 ,  A61K2039/505 ,  C07K14/47 ,  C12N2799/026 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2500/10 ,  G01N2800/065 ,  G01N2800/205 ,  G01N2800/24

Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases involving detection of the PRO52254 polypeptide.

公开(公告)号：USRE46805E1

公开(公告)日：2018-04-24

申请号：US14228172

申请日：2014-03-27

Applicant: Genentech, Inc.

Inventor： Daryl T. Baldwin ,  Sarah C. Bodary-Winter ,  Andrew C. Chan ,  Hilary Clark ,  Janet K. Jackman ,  William I. Wood

IPC: G01N33/53 ,  C07K16/18 ,  C07K14/47 ,  C12Q1/68 ,  A61K39/00

CPC classification number: C07K16/18 ,  A61K2039/505 ,  C07K14/47 ,  C12N2799/026 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2500/10 ,  G01N2800/065 ,  G01N2800/205 ,  G01N2800/24

Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases involving detection of the PRO52254 polypeptide.

公开(公告)号：USRE46534E1

公开(公告)日：2017-09-05

申请号：US14699845

申请日：2015-04-29

Applicant: Genentech, Inc.

Inventor： Daryl T. Baldwin ,  Sarah C. Bodary-Winter ,  Andrew C. Chan ,  Hilary Clark ,  Janet K. Jackman ,  William I. Wood

IPC: G01N33/53 ,  C07K16/18 ,  C07K14/47 ,  C12Q1/68 ,  A61K39/00

CPC classification number: C07K16/18 ,  A61K2039/505 ,  C07K14/47 ,  C12N2799/026 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2500/10 ,  G01N2800/065 ,  G01N2800/205 ,  G01N2800/24

Abstract: The present invention relates to compositions containing a novel protein and methods of using those compositions for the diagnosis and treatment of immune related diseases involving detection of the PRO52254 polypeptide.

公开(公告)号：US20140154242A1

公开(公告)日：2014-06-05

申请号：US14029717

申请日：2013-09-17

Applicant: Genentech, Inc.

Inventor： Camellia W. ADAMS ,  Andrew C. Chan ,  Craig W. Crowley ,  Henry B. Lowman ,  Gerald R. Nakamura ,  Leonard G. Presta

IPC: C07K16/28

CPC classification number: C07K16/2887 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/41 ,  C07K2317/52 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/72 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/75 ,  C07K2317/92

Abstract: The invention provides humanized and chimeric anti-CD20 antibodies for treatment of CD20 positive malignancies and autoimmune diseases.

Abstract translation: 本发明提供用于治疗CD20阳性恶性肿瘤和自身免疫疾病的人源化和嵌合抗CD20抗体。