公开(公告)号：US20170158773A1

公开(公告)日：2017-06-08

申请号：US15217838

申请日：2016-07-22

Applicant: Genentech, Inc.

Inventor： Camellia W. ADAMS ,  Andrew C. CHAN ,  Craig W. CROWLEY ,  Henry B. LOWMAN ,  Gerald R. NAKAMURA ,  Leonard G. PRESTA

IPC: C07K16/28

CPC classification number: C07K16/2887 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/41 ,  C07K2317/52 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/72 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/75 ,  C07K2317/92

Abstract: The invention provides humanized and chimeric anti-CD20 antibodies for treatment of CD20 positive malignancies and autoimmune diseases.

公开(公告)号：US20220002430A1

公开(公告)日：2022-01-06

申请号：US17235805

申请日：2021-04-20

Applicant: Genentech, Inc.

Inventor： Camellia W. ADAMS ,  Andrew C. CHAN ,  Craig W. CROWLEY ,  Henry B. LOWMAN ,  Gerald R. NAKAMURA ,  Leonard G. PRESTA

IPC: C07K16/28

Abstract: The invention provides humanized and chimeric anti-CD20 antibodies for treatment of CD20 positive malignancies and autoimmune diseases.

公开(公告)号：US20190071511A1

公开(公告)日：2019-03-07

申请号：US15905406

申请日：2018-02-26

Applicant: Genentech, Inc.

Inventor： Camellia W. ADAMS ,  Andrew C. CHAN ,  Craig W. CROWLEY ,  Henry B. LOWMAN ,  Gerald R. NAKAMURA ,  Leonard G. PRESTA

IPC: C07K16/28 ,  A61K39/00

Abstract: The invention provides humanized and chimeric anti-CD20 antibodies for treatment of CD20 positive malignancies and autoimmune diseases.

公开(公告)号：US20140154242A1

公开(公告)日：2014-06-05

申请号：US14029717

申请日：2013-09-17

Applicant: Genentech, Inc.

Inventor： Camellia W. ADAMS ,  Andrew C. Chan ,  Craig W. Crowley ,  Henry B. Lowman ,  Gerald R. Nakamura ,  Leonard G. Presta

IPC: C07K16/28

CPC classification number: C07K16/2887 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/41 ,  C07K2317/52 ,  C07K2317/522 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/72 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/75 ,  C07K2317/92

Abstract: The invention provides humanized and chimeric anti-CD20 antibodies for treatment of CD20 positive malignancies and autoimmune diseases.

Abstract translation: 本发明提供用于治疗CD20阳性恶性肿瘤和自身免疫疾病的人源化和嵌合抗CD20抗体。