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1.发明授权公开(公告)号：US08579928B2
公开(公告)日：2013-11-12
申请号：US12703885
申请日：2010-02-11
IPC分类号： A61B17/32
CPC分类号： A61B17/320068 , A61B17/320783 , A61B2017/00261 , A61B2017/320072 , A61B2017/320084 , A61B2017/320791 , A61B2217/005
摘要： In various embodiments, a surgical instrument for operation in an aqueous environment is provided. In at least one embodiment, the surgical instrument may include a hollow sheath, a blade disposed at least partially within the hollow sheath and extending through an opening in the sheath, and at least one ultrasonic transducer operably coupled to the blade. The blade may include a polygonal cross-sectional shape and the tip may project away from the sheath's longitudinal axis. In another embodiment, the surgical instrument may include a blade with suction disposed therethrough and at least one ultrasonic transducer operably coupled to the blade. The blade may include a cutting edge that is positioned over a blade opening. Also, the cutting edge may project away from the blade's longitudinal axis.
摘要翻译： 在各种实施例中，提供了用于在水性环境中操作的外科器械。 在至少一个实施例中，外科器械可以包括中空护套，至少部分地设置在中空护套内并且延伸穿过护套中的开口的刀片以及可操作地联接到刀片的至少一个超声换能器。 刀片可以包括多边形横截面形状，并且尖端可以突出远离护套的纵向轴线。 在另一个实施例中，外科器械可以包括具有穿过其中的抽吸的刀片和可操作地联接到刀片的至少一个超声换能器。 叶片可以包括位于叶片开口上方的切割边缘。 此外，切削刃可以从刀片的纵向轴线突出。
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公开(公告)号：US20110196403A1
公开(公告)日：2011-08-11
申请号：US12703885
申请日：2010-02-11
IPC分类号： A61B17/32
CPC分类号： A61B17/320068 , A61B17/320783 , A61B2017/00261 , A61B2017/320072 , A61B2017/320084 , A61B2017/320791 , A61B2217/005
摘要： In various embodiments, a surgical instrument for operation in an aqueous environment is provided. In at least one embodiment, the surgical instrument may include a hollow sheath, a blade disposed at least partially within the hollow sheath and extending through an opening in the sheath, and at least one ultrasonic transducer operably coupled to the blade. The blade may include a polygonal cross-sectional shape and the tip may project away from the sheath's longitudinal axis. In another embodiment, the surgical instrument may include a blade with suction disposed therethrough and at least one ultrasonic transducer operably coupled to the blade. The blade may include a cutting edge that is positioned over a blade opening. Also, the cutting edge may project away from the blade's longitudinal axis.
摘要翻译： 在各种实施例中，提供了用于在水性环境中操作的外科器械。 在至少一个实施例中，外科器械可以包括中空护套，至少部分地设置在中空护套内并且延伸穿过护套中的开口的刀片以及可操作地联接到刀片的至少一个超声换能器。 刀片可以包括多边形横截面形状，并且尖端可以突出远离护套的纵向轴线。 在另一个实施例中，外科器械可以包括具有穿过其中的抽吸的刀片和可操作地联接到刀片的至少一个超声换能器。 叶片可以包括位于叶片开口上方的切割边缘。 此外，切削刃可以从刀片的纵向轴线突出。
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3.发明授权Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods 有权肠内制动诱导管腔内治疗物质洗脱装置及方法公开(公告)号：US08876761B2
公开(公告)日：2014-11-04
申请号：US13104313
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M31/00 , A61K9/00 , A61M5/142 , A61F5/00 , A61N1/05 , A61M39/02 , A61F2/04 , A61N1/36 , A61N1/372
CPC分类号： A61M31/002 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F2002/045 , A61K9/0065 , A61M5/14276 , A61M39/0208 , A61M2210/106 , A61M2210/1064 , A61N1/0509 , A61N1/36007 , A61N1/37205
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。 植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质 从植入物到胃肠道。
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4.发明授权Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods 有权肠内制动诱导管腔内治疗物质洗脱装置及方法公开(公告)号：US08603023B2
公开(公告)日：2013-12-10
申请号：US13105029
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F5/0079 , A61F2002/045
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，可植入系统包括将治疗物质递送到患者胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。
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5.发明授权公开(公告)号：US08531064B2
公开(公告)日：2013-09-10
申请号：US12703860
申请日：2010-02-11
申请人： Galen C. Robertson , Richard W. Timm , Daniel J. Mumaw , Foster B. Stulen , Gregory W. Johnson , Jerome R. Morgan , Kevin L. Houser , Kristi M. Bodin , Mark A. Neurohr , Prasanna Malaviya , Reginald D. Fortson , Sean P. Conlon , William S. Joachim, Jr. , William D. Dannaher , Eitan T. Wiener
发明人： Galen C. Robertson , Richard W. Timm , Daniel J. Mumaw , Foster B. Stulen , Gregory W. Johnson , Jerome R. Morgan , Kevin L. Houser , Kristi M. Bodin , Mark A. Neurohr , Prasanna Malaviya , Reginald D. Fortson , Sean P. Conlon , William S. Joachim, Jr. , William D. Dannaher , Eitan T. Wiener
IPC分类号： H02K7/12
CPC分类号： A61B17/320068 , A61B17/32002 , A61B17/320092 , A61B17/320758 , A61B2017/00075 , A61B2017/00106 , A61B2017/00477 , A61B2017/320072
摘要： In one general aspect, various embodiments are directed to an ultrasonic surgical instrument that comprises a handpiece housing that rotatably supports an ultrasonic transducer assembly therein that may be selectively rotated by various motor configurations. Various slip ring arrangements are disclosed for supplying ultrasonic electrical signals and motor drive signals from a control system. Various forms of blade and cutting implements are disclosed for attachment to the ultrasonic transducer assembly such that such implements may be selectively rotatable within a hollow outer sheath. Vacuum may be applied to the cutting implement or through the outer sheath to draw tissue through an opening in the sheath and into contact with the cutting implement.
摘要翻译： 在一个一般方面，各种实施例涉及一种超声波手术器械，其包括可旋转地支撑超声波换能器组件的手持件壳体，该超声波换能器组件可以通过各种电机配置选择性地旋转。 公开了用于从控制系统提供超声波电信号和电机驱动信号的各种滑环装置。 公开了各种形式的刀片和切割工具用于附接到超声换能器组件，使得这样的器具可以在中空的外护套内选择性地旋转。 可以将真空施加到切割工具或通过外护套将组织穿过护套中的开口并与切割工具接触。
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6.发明申请公开(公告)号：US20110196286A1
公开(公告)日：2011-08-11
申请号：US12703860
申请日：2010-02-11
申请人： Galen C. Robertson , Richard W. Timm , Daniel J. Mumaw , Foster B. Stulen , Gregory W. Johnson , Jerome R. Morgan , Kevin L. Houser , Kristi M. Bodin , Mark A. Neurohr , Prasanna Malaviya , Reginald D. Fortson , Sean P. Conlon , William S. Joachim, JR. , William D. Dannaher , Eitan T. Wiener
发明人： Galen C. Robertson , Richard W. Timm , Daniel J. Mumaw , Foster B. Stulen , Gregory W. Johnson , Jerome R. Morgan , Kevin L. Houser , Kristi M. Bodin , Mark A. Neurohr , Prasanna Malaviya , Reginald D. Fortson , Sean P. Conlon , William S. Joachim, JR. , William D. Dannaher , Eitan T. Wiener
IPC分类号： A61B17/32
CPC分类号： A61B17/320068 , A61B17/32002 , A61B17/320092 , A61B17/320758 , A61B2017/00075 , A61B2017/00106 , A61B2017/00477 , A61B2017/320072
摘要： In one general aspect, various embodiments are directed to an ultrasonic surgical instrument that comprises a handpiece housing that rotatably supports an ultrasonic transducer assembly therein that may be selectively rotated by various motor configurations. Various slip ring arrangements are disclosed for supplying ultrasonic electrical signals and motor drive signals from a control system. Various forms of blade and cutting implements are disclosed for attachment to the ultrasonic transducer assembly such that such implements may be selectively rotatable within a hollow outer sheath. Vacuum may be applied to the cutting implement or through the outer sheath to draw tissue through an opening in the sheath and into contact with the cutting implement.
摘要翻译： 在一个一般方面，各种实施例涉及一种超声波手术器械，其包括可旋转地支撑超声波换能器组件的手持件壳体，该超声波换能器组件可以通过各种电机配置选择性地旋转。 公开了用于从控制系统提供超声波电信号和电机驱动信号的各种滑环装置。 公开了各种形式的刀片和切割工具用于附接到超声换能器组件，使得这样的器具可以在中空的外护套内选择性地旋转。 可以将真空施加到切割工具或通过外护套将组织穿过护套中的开口并与切割工具接触。
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7.发明申请INTESTINAL BRAKE INDUCING INTRALUMINAL THERAPEUTIC SUBSTANCE ELUTING DEVICES AND METHODS 有权INTESTINAL BRAKE INDING IN INTRALUMINAL THERAPEUTIC THEAPEUTIC TYSTURE ELDTING ELTERTING DEVICES AND METHODS公开(公告)号：US20110295180A1
公开(公告)日：2011-12-01
申请号：US13105029
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F5/0079 , A61F2002/045
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，可植入系统包括将治疗物质递送到患者胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。
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公开(公告)号：US20110295056A1
公开(公告)日：2011-12-01
申请号：US13104223
申请日：2011-05-10
申请人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Lauren S. Weaner , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
发明人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Lauren S. Weaner , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
IPC分类号： A61F2/04
CPC分类号： A61F5/0083 , A61B17/00234 , A61B17/064 , A61B17/12136 , A61B17/12159 , A61B17/1355 , A61B2017/00035 , A61B2017/00557 , A61B2017/00632 , A61B2017/00818 , A61B2017/00898 , A61B2017/1142 , A61F5/004 , A61F5/0056
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
摘要翻译： 用于改变胃体积的装置和方法包括形成胃内狭槽，用于以最小的神经和脉管系统流动的干扰来包裹眼底的一个或多个部分。 内部空间占据装置随着消化循环固有的自然条件（如pH变化）带来的环境变化而扩大。 腹腔积气囊放置在折叠的胃部。 气囊流体地联接到外部胃灌注装置。 在另一组实施方案中，方法和装置提供可调节的胃体积减少基底包裹。 在一个实施例中，将装置放置在眼底以进行尼森眼底切开术，并允许术后调整以达到期望的体重减轻。 肠内和胃内气囊任选并入。
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公开(公告)号：US20110295057A1
公开(公告)日：2011-12-01
申请号：US13105001
申请日：2011-05-11
申请人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
发明人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
IPC分类号： A61F2/04
CPC分类号： A61F5/0083 , A61F5/003 , A61F5/0033 , A61F5/0036 , A61F5/004 , A61F5/0043 , A61F5/005 , A61F5/0053 , A61F5/0056 , A61F5/0073 , A61F5/0086
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
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10.发明授权公开(公告)号：US08636751B2
公开(公告)日：2014-01-28
申请号：US13104192
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , Mario Gutierrez , Prasanna Malaviya , Amy L. Marcotte , Jeffrey D. Messerly , Anthony Nguyen , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , Lauren S. Weaner , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , Mark S. Zeiner
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , Mario Gutierrez , Prasanna Malaviya , Amy L. Marcotte , Jeffrey D. Messerly , Anthony Nguyen , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , Lauren S. Weaner , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , Mark S. Zeiner
IPC分类号： A61B17/10
CPC分类号： A61B17/00234 , A61B5/0031 , A61B5/036 , A61B5/073 , A61B5/076 , A61B5/1107 , A61B5/14532 , A61B5/14539 , A61B5/42 , A61B17/0469 , A61B17/1114 , A61B2017/00876 , A61B2017/1117 , A61B2017/1139 , A61B2560/0219 , A61F2/04 , A61F5/0013 , A61F2002/045
摘要： Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may include one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.
摘要翻译： 方法和装置重新路由食糜诱导肠道制动，以提高减肥手术的有效性和改善共病分解。 肠道被操纵以提供用于食糜行进到回肠的缩短路径。 用于诱导肠内制动器的这些重新路由食糜的方法和装置可以包括外科手术，植入装置或具有改进的外科手术的植入物的组合中的一种或多种。
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