公开(公告)号：US20140255272A1

公开(公告)日：2014-09-11

申请号：US14285099

申请日：2014-05-22

Applicant: General Electric Company

Inventor： Robert Scott Duthie ,  Wei-Cheng Tian ,  Tarun Khurana

IPC: G01N1/34

CPC classification number: G01N1/34 ,  B01L3/50273 ,  C12M23/16 ,  C12M47/12 ,  C12N15/1003 ,  G01N27/447 ,  G01N30/24

Abstract: Embodiments of the present techniques provide systems and methods for isolating particular classes of biological molecules, for example, proteins or nucleic acids, from mixtures of biological components. The methods use solutions that react with the biological molecules to enhance their adsorption by substrates, allowing contaminants to be washed away from the targeted molecules. Embodiments include automated systems that can be used to implement the technique with no or minimal intervention. Other embodiments include separation column technologies that may be used in the techniques.

Abstract translation: 本技术的实施方案提供了从生物组分的混合物中分离特定类别的生物分子例如蛋白质或核酸的系统和方法。 该方法使用与生物分子反应的溶液，以增强其对底物的吸附，从而使污染物从目标分子中被冲走。 实施例包括可用于实现没有或最小干预的技术的自动化系统。 其他实施方案包括可用于该技术的分离塔技术。

公开(公告)号：US09506847B2

公开(公告)日：2016-11-29

申请号：US14285099

申请日：2014-05-22

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Robert Scott Duthie ,  Wei-Cheng Tian ,  Tarun Khurana

IPC: G01N1/34 ,  C12M3/06 ,  C12M1/00 ,  C12N15/10 ,  B01L3/00 ,  G01N27/447 ,  G01N30/24

CPC classification number: G01N1/34 ,  B01L3/50273 ,  C12M23/16 ,  C12M47/12 ,  C12N15/1003 ,  G01N27/447 ,  G01N30/24

Abstract: Embodiments of the present techniques provide systems and methods for isolating particular classes of biological molecules, for example, proteins or nucleic acids, from mixtures of biological components. The methods use solutions that react with the biological molecules to enhance their adsorption by substrates, allowing contaminants to be washed away from the targeted molecules. Embodiments include automated systems that can be used to implement the technique with no or minimal intervention. Other embodiments include separation column technologies that may be used in the techniques.

Abstract translation: 本技术的实施方案提供了从生物组分的混合物中分离特定类别的生物分子例如蛋白质或核酸的系统和方法。 该方法使用与生物分子反应的溶液，以增强其对底物的吸附，从而使污染物从目标分子中被冲走。 实施例包括可用于实现没有或最小干预的技术的自动化系统。 其他实施方案包括可用于该技术的分离塔技术。