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公开(公告)号：US20230063741A1
公开(公告)日：2023-03-02
申请号：US17721970
申请日：2022-04-15
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH , Ganesh A. KOLUMAM , Xiaoting WANG , Jed ROSS , Nicholas VAN BRUGGEN , Wyne P. LEE
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US20190177389A1
公开(公告)日：2019-06-13
申请号：US16196829
申请日：2018-11-20
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH , Ganesh A. KOLUMAM , Xiaoting WANG , Jed ROSS , Nicholas VAN BRUGGEN , Wyne P. LEE
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US20170320926A1
公开(公告)日：2017-11-09
申请号：US15454662
申请日：2017-03-09
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH , Ganesh A. KOLUMAM , Xiaoting WANG , Jed ROSS , Nicholas VAN BRUGGEN , Wyne P. LEE
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US20150266953A1
公开(公告)日：2015-09-24
申请号：US14581971
申请日：2014-12-23
Applicant: GENENTECH, INC.
Inventor： Jian CHEN , Ellen FILVAROFF , Sherman FONG , Dorothy FRENCH , Audrey GODDARD , Paul J. GODOWSKI , J. Christopher GRIMALDI , Austin L. GUMEY , Kenneth J. HILLAN , Sarah G. HYMOWITZ , Hanzhong LI , James Pan ZTUBICOKE , Melissa A. STAROVASNIK , Daniel TUMAS , Menno VAN LOOKEREN , Richard VANDLEN , Colin K. WATANABE , P. Mickey WILLIAMS , William I. WOOD , Daniel G. YANSURA
CPC classification number: C07K16/244 , A61K38/00 , C07H21/04 , C07K14/54 , C07K14/7155 , C07K2317/21 , C07K2317/24 , C07K2317/35 , C07K2317/54 , C07K2317/55 , C07K2317/62 , G01N33/505 , G01N33/564 , G01N33/574 , G01N33/57407 , G01N33/57423 , G01N33/57438 , G01N33/57492 , G01N2333/54 , G01N2333/7155
Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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公开(公告)号：US20190177388A1
公开(公告)日：2019-06-13
申请号：US16196823
申请日：2018-11-20
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH , Ganesh A. KOLUMAM , Xiaoting WANG , Jed ROSS , Nicholas VAN BRUGGEN , Wyne P. LEE
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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Patent Agency Ranking
公开(公告)号：US20180362608A1
公开(公告)日：2018-12-20
申请号：US15801867
申请日：2017-11-02
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH , Ganesh A. KOLUMAM , Xiaoting WANG , Jed ROSS , Nicholas VAN BRUGGEN , Wyne P. LEE
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US20190177386A1
公开(公告)日：2019-06-13
申请号：US16196741
申请日：2018-11-20
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH , Ganesh A. KOLUMAM , Xiaoting WANG , Jed ROSS , Nicholas VAN BRUGGEN , Wyne P. LEE
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US20150141283A1
公开(公告)日：2015-05-21
申请号：US14489167
申请日：2014-09-17
Applicant: GENENTECH, INC.
Inventor： Jian CHEN , Ellen FILVAROFF , Sherman FONG , Dorothy FRENCH , Audrey GODDARD , Paul J. GODOWSKI , J. Christopher GRIMALDI , Austin L. GURNEY , Kenneth J. HILIAN , Sarah G. HYMOWITZ , Hanzhong LI , Melissa A. STAROVASNIK , Daniel TUMAS , Menno VAN LOOKEREN , Richard VANDLEN , Colin K. WATANABE , P. Mickey WILLIAMS , William I. WOOD , Daniel G. YANSURA , James PAN
IPC: G01N33/574
CPC classification number: C07K16/244 , A61K38/00 , C07H21/04 , C07K14/54 , C07K14/7155 , C07K2317/21 , C07K2317/24 , C07K2317/35 , C07K2317/54 , C07K2317/55 , C07K2317/62 , G01N33/505 , G01N33/564 , G01N33/574 , G01N33/57407 , G01N33/57423 , G01N33/57438 , G01N33/57492 , G01N2333/54 , G01N2333/7155
Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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公开(公告)号：US20180355009A1
公开(公告)日：2018-12-13
申请号：US16049633
申请日：2018-07-30
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH
CPC classification number: C07K14/54 , A61K31/573 , A61K38/20 , A61K45/06 , A61P1/04 , C07K7/06 , C07K2319/30
Abstract: The invention relates to IL-22 Fc fusion protein, composition comprising the IL-22 Fc fusion protein, and method of using the composition for the treatment of diseases, especially inflammatory bowel diseases.
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公开(公告)号：US20170088596A1
公开(公告)日：2017-03-30
申请号：US15369236
申请日：2016-12-05
Applicant: Genentech, Inc.
Inventor： Justin SCHEER , Wenjun OUYANG , Richard VANDLEN , Philip E. HASS , Eric Gary STEFANICH , Ganesh A. KOLUMAM , Xiaoting WANG , Jed ROSS , Nicholas VAN BRUGGEN , Wyne P. LEE
IPC: C07K14/54
CPC classification number: C07K14/54 , A61K38/00 , A61K38/20 , A61K47/38 , C07K16/2866 , C07K2319/30
Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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