-
公开(公告)号:US11666868B2
公开(公告)日:2023-06-06
申请号:US17590085
申请日:2022-02-01
Applicant: GAMBRO LUNDIA AB
Inventor: Adriana Boschetti-De-Fierro , Manuel Voigt , Bernd Krause , Markus Hornung , Markus Storr , Heinrich Behr , Werner Beck , Carina Zweigart , Reinhold Buck , Philipp Herbst , Joachim Loercher , Arnd Wochner
CPC classification number: B01D71/68 , A61M1/1621 , A61M1/3413 , B01D61/243 , B01D63/021 , B01D69/081 , B01D69/084 , B01D69/087 , B01D71/38 , B01D71/44 , A61M1/16 , B01D2323/06 , B01D2323/12 , B01D2325/022 , B01D2325/025 , B01D2325/026 , B01D2325/04 , B01D2325/20
Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
-
公开(公告)号:US11413384B2
公开(公告)日:2022-08-16
申请号:US16762623
申请日:2018-12-10
Applicant: GAMBRO LUNDIA AB
Inventor: Joachim Loercher , Juergen Eichinger , Reinhold Buck , Arnd Wochner
Abstract: The present disclosure relates to capillary dialyzers for blood purification, in particular, capillary dialyzers suitable for home hemodialysis systems.
-
公开(公告)号:US12059658B2
公开(公告)日:2024-08-13
申请号:US18143325
申请日:2023-05-04
Applicant: GAMBRO LUNDIA AB
Inventor: Adriana Boschetti-De-Fierro , Manuel Voigt , Bernd Krause , Markus Hornung , Markus Storr , Heinrich Behr , Werner Beck , Carina Zweigart , Reinhold Buck , Philipp Herbst , Joachim Loercher , Arnd Wochner
CPC classification number: B01D71/68 , A61M1/1621 , A61M1/3413 , B01D61/243 , B01D63/0233 , B01D69/081 , B01D69/084 , B01D69/087 , B01D71/381 , B01D71/441 , A61M1/16 , B01D2323/06 , B01D2323/12 , B01D2325/022 , B01D2325/025 , B01D2325/026 , B01D2325/04 , B01D2325/20
Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
-
公开(公告)号:US10022481B2
公开(公告)日:2018-07-17
申请号:US14893688
申请日:2014-06-19
Applicant: GAMBRO LUNDIA AB
Inventor: Markus Hornung , Arnd Wochner , Reinhold Buck , Helmut Hildwein , Nikolaus Kanarjow
Abstract: The present disclosure relates to capillary dialyzers for blood purification comprising from 85-95% crimped fibers and from 5-15% non-crimped fibers.
-
公开(公告)号:US12145108B2
公开(公告)日:2024-11-19
申请号:US17786685
申请日:2020-12-21
Applicant: GAMBRO LUNDIA AB
Inventor: Reinhold Buck , Evelyn Grossmann , Markus Hornung , Markus Loeffler , Heinrich Behr , Arnd Wochner , Carl-Philipp Scheuermann
IPC: B01D69/08 , B01D71/44 , B01D71/68 , B29C48/00 , B29C48/05 , B29C48/09 , B29C48/32 , B29C48/345 , B29K81/00 , B29L31/00 , D01D5/06 , D01D5/24 , D01F6/76
Abstract: The present disclosure relates to a spinneret for producing hollow fiber membranes in a phase inversion process.
-
公开(公告)号:US11666869B2
公开(公告)日:2023-06-06
申请号:US17590097
申请日:2022-02-01
Applicant: GAMBRO LUNDIA AB
Inventor: Markus Hornung , Bernd Krause , Markus Storr , Philipp Herbst , Arnd Wochner , Adriana Boschetti-De-Fierro , Manuel Voigt , Carina Zweigart , Joachim Loercher , Reinhold Buck , Heinrich Behr , Werner Beck
CPC classification number: B01D71/68 , A61M1/3479 , B01D61/243 , B01D63/021 , B01D69/084 , B01D69/087 , B01D71/38 , B01D71/44 , B01D2323/06 , B01D2323/12 , B01D2325/022 , B01D2325/20
Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
-
公开(公告)号:US11273416B2
公开(公告)日:2022-03-15
申请号:US16851432
申请日:2020-04-17
Applicant: GAMBRO LUNDIA AB
Inventor: Adriana Boschetti-De-Fierro , Manuel Voigt , Bernd Krause , Markus Hornung , Markus Storr , Heinrich Behr , Werner Beck , Carina Zweigart , Reinhold Buck , Philipp Herbst , Joachim Loercher , Arnd Wochner
Abstract: The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
-
公开(公告)号:US11273417B2
公开(公告)日:2022-03-15
申请号:US16851439
申请日:2020-04-17
Applicant: GAMBRO LUNDIA AB
Inventor: Markus Hornung , Bernd Krause , Markus Storr , Philipp Herbst , Arnd Wochner , Adriana Boschetti-De-Fierro , Manuel Voigt , Carina Zweigart , Joachim Loercher , Reinhold Buck , Heinrich Behr , Werner Beck
Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
-
公开(公告)号:US11154820B2
公开(公告)日:2021-10-26
申请号:US15538533
申请日:2015-12-21
Applicant: GAMBRO LUNDIA AB
Inventor: Ulrich Bauer , Reinhold Buck , Juergen Graf , Helmut Hildwein , Bernd Krause , Markus Storr , Arnd Wochner
Abstract: The present invention relates to a continuous process for preparing permselective hollow fiber membranes being suitable e.g. for hemodialysis, hemodiafiltration and hemofiltration of blood which comprises a two-stage drying and tempering treatment of the hollow fiber membranes. According to a further aspect, the invention relates to a continuous process for drying permselective hollow fiber membranes on-line. The invention also relates to devices for on-line drying of permselective hollow fiber membranes.
-
公开(公告)号:US12059657B2
公开(公告)日:2024-08-13
申请号:US18143324
申请日:2023-05-04
Applicant: GAMBRO LUNDIA AB
Inventor: Markus Hornung , Bernd Krause , Markus Storr , Philipp Herbst , Arnd Wochner , Adriana Boschetti-De-Fierro , Manuel Voigt , Carina Zweigart , Joachim Loercher , Reinhold Buck , Heinrich Behr , Werner Beck
CPC classification number: B01D71/68 , A61M1/3479 , B01D61/243 , B01D63/0233 , B01D69/084 , B01D69/087 , B01D71/381 , B01D71/441 , B01D2323/06 , B01D2323/12 , B01D2325/022 , B01D2325/20
Abstract: The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
-
-
-
-
-
-
-
-
-