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公开(公告)号:US11998610B2
公开(公告)日:2024-06-04
申请号:US17173498
申请日:2021-02-11
发明人: Spencer Cory Peck , Steven John Taylor , Elijah Lane Bogart , Devin Forest Reed Doud , Joo Hyun Im , Dervla Tamara Isaac , Jenny Liu , Ferdinand Edward Massari , Robert Walter Myers , John Robert Proudfoot , Cheri Ross , John Patrick Casey, Jr. , David Arthur Berry
IPC分类号: A61K47/65 , A61K47/54 , A61P31/04 , A61P35/00 , C07D239/553 , C07D311/16 , C07D491/22 , C07H19/06 , C07K5/02 , C07K5/062 , C07K5/065 , C07K5/068 , C07K5/078
CPC分类号: A61K47/65 , A61K47/542 , A61P31/04 , A61P35/00 , C07D239/553 , C07D311/16 , C07D491/22 , C07H19/06 , C07K5/0205 , C07K5/06017 , C07K5/06034 , C07K5/06078 , C07K5/06086 , C07K5/06139
摘要: Disclosed are conjugates including a recognition element covalently bonded to or linked through a linker to a payload. The payload is a pharmaceutical agent (e.g., an antineoplastic agent, anti-infective agent, or anti-inflammatory agent) or a diagnostic agent. Also disclosed are methods of using the conjugates.
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公开(公告)号:US11813272B2
公开(公告)日:2023-11-14
申请号:US16950120
申请日:2020-11-17
发明人: Steven John Taylor , John Robert Proudfoot , Mi-Jeong Kim , Kathleen Nudel , Timothy F. Briggs , Afrand Kamali Sarvestani , Leonard Buckbinder , Bernard Lanter , Ferdinand Edward Massari , Koji Yasuda , Spencer Cory Peck , Cheri Snedeker , Diana Le , Jessica Alexander , Anna Liang , Dinara Gunasekera , David Arthur Berry , John Patrick Casey, Jr.
IPC分类号: A61K31/7028 , A61P3/10 , A61K45/06
CPC分类号: A61K31/7028 , A61K45/06 , A61P3/10
摘要: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.
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公开(公告)号:US10953027B2
公开(公告)日:2021-03-23
申请号:US16803411
申请日:2020-02-27
发明人: Steven John Taylor , John Robert Proudfoot , Mi-Jeong Kim , Kathleen Nudel , Timothy F. Briggs , Afrand Kamali Sarvestani , Leonard Buckbinder , Bernard Lanter , Ferdinand Edward Massari , Koji Yasuda , Spencer Cory Peck , Cheri Snedeker , Diana Le , Jessica Alexander , Anna Liang , Dinara Gunasekera , David Arthur Berry , John Patrick Casey, Jr.
IPC分类号: A61K31/7028 , A61K45/06 , A61P3/10
摘要: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.
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