公开(公告)号：US11813272B2

公开(公告)日：2023-11-14

申请号：US16950120

申请日：2020-11-17

申请人： Flagship Pioneering Innovations V, Inc.

发明人： Steven John Taylor ,  John Robert Proudfoot ,  Mi-Jeong Kim ,  Kathleen Nudel ,  Timothy F. Briggs ,  Afrand Kamali Sarvestani ,  Leonard Buckbinder ,  Bernard Lanter ,  Ferdinand Edward Massari ,  Koji Yasuda ,  Spencer Cory Peck ,  Cheri Snedeker ,  Diana Le ,  Jessica Alexander ,  Anna Liang ,  Dinara Gunasekera ,  David Arthur Berry ,  John Patrick Casey, Jr.

IPC分类号： A61K31/7028 ,  A61P3/10 ,  A61K45/06

CPC分类号： A61K31/7028 ,  A61K45/06 ,  A61P3/10

摘要： Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

公开(公告)号：US10953027B2

公开(公告)日：2021-03-23

申请号：US16803411

申请日：2020-02-27

申请人： Flagship Pioneering Innovations V, Inc.

发明人： Steven John Taylor ,  John Robert Proudfoot ,  Mi-Jeong Kim ,  Kathleen Nudel ,  Timothy F. Briggs ,  Afrand Kamali Sarvestani ,  Leonard Buckbinder ,  Bernard Lanter ,  Ferdinand Edward Massari ,  Koji Yasuda ,  Spencer Cory Peck ,  Cheri Snedeker ,  Diana Le ,  Jessica Alexander ,  Anna Liang ,  Dinara Gunasekera ,  David Arthur Berry ,  John Patrick Casey, Jr.

IPC分类号： A61K31/7028 ,  A61K45/06 ,  A61P3/10

摘要： Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

公开(公告)号：US12115178B2

公开(公告)日：2024-10-15

申请号：US17557772

申请日：2021-12-21

申请人： Flagship Pioneering Innovations V, Inc.

发明人： Steven John Taylor ,  Mi-Jeong Kim ,  Kathleen Nudel ,  Timothy F. Briggs ,  Koji Yasuda ,  Leonard Buckbinder ,  Bernard Lanter ,  Spencer Cory Peck ,  Cheri Snedeker ,  Angela She ,  Jessica Alexander ,  Anna Liang ,  Jenny Liu ,  Dinara Gunasekera ,  David Arthur Berry ,  John Patrick Casey, Jr. ,  Amir H. Moarefi

IPC分类号： A61K31/7036 ,  A61K9/00 ,  A61K31/191 ,  A61K31/196 ,  A61K31/353 ,  A61K31/519 ,  A61P37/06

CPC分类号： A61K31/7036 ,  A61K9/0053 ,  A61K31/191 ,  A61K31/196 ,  A61K31/353 ,  A61K31/519 ,  A61P37/06

摘要： Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.

公开(公告)号：US11058698B2

公开(公告)日：2021-07-13

申请号：US16803284

申请日：2020-02-27

申请人： Flagship Pioneering Innovations V, Inc.

发明人： Steven John Taylor ,  Mi-Jeong Kim ,  Kathleen Nudel ,  Timothy F. Briggs ,  Koji Yasuda ,  Leonard Buckbinder ,  Bernard Lanter ,  Spencer Cory Peck ,  Cheri Snedeker ,  Angela She ,  Jessica Alexander ,  Anna Liang ,  Jenny Liu ,  Dinara Gunasekera ,  David Arthur Berry ,  John Patrick Casey, Jr. ,  Amir H. Moarefi

IPC分类号： A61K31/7036 ,  A61K31/191 ,  A61K31/196 ,  A61K9/00 ,  A61P37/06 ,  A61K31/353 ,  A61K31/519

摘要： Disclosed herein are acylated active agents and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.