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1.发明申请Extrapallial fluid of molluscs, methods of obtaining same, formulation and use thereof 审中-公开软体动物的外部液体，获得其的方法，制剂和用途公开(公告)号：US20070128293A1
公开(公告)日：2007-06-07
申请号：US10587968
申请日：2005-02-14
申请人： Evelyne Lopez , Xavier Bourrat , Marthe Rousseau
发明人： Evelyne Lopez , Xavier Bourrat , Marthe Rousseau
CPC分类号： A61K35/618
摘要： The invention relates to a fluid preparation method comprising the recovery of the fluid that is located between the shell and the body of a mollusc. The invention also relates to the liquid obtained using said method, and to the use thereof in the pharmaceutical field, in particular in order to improve cutaneous healing, to regenerate tissues or to promote osteogenesis or bone mineralization. The invention further relates to compositions, particularly pharmaceutical compositions, medical devices or food supplements containing same.
摘要翻译： 本发明涉及一种流体制备方法，其包括回收位于壳体和软体动物体内的流体。 本发明还涉及使用所述方法获得的液体及其在制药领域中的应用，特别是为了改善皮肤愈合，再生组织或促进成骨或骨矿化。 本发明还涉及包含其的组合物，特别是药物组合物，医疗装置或食品补充剂。
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公开(公告)号：US20120071414A1
公开(公告)日：2012-03-22
申请号：US13262909
申请日：2010-04-09
申请人： Xavier Bourrat , Evelyne Lopez , Marthe Rousseau
发明人： Xavier Bourrat , Evelyne Lopez , Marthe Rousseau
IPC分类号： A61K8/64 , A61K31/70 , A61K31/20 , C07K1/14 , C07H1/08 , C11B1/10 , A61P19/00 , A61P19/02 , A61P19/08 , A61P19/10 , A61P17/00 , A61Q19/08 , A61Q19/00 , A61K8/60 , A61K8/36 , A61K38/02
CPC分类号： B01D11/0288 , A61K8/965 , A61K35/02 , A61Q19/08
摘要： The present invention relates to a method for extracting organic molecules and/or organic minerals from a limestone material, including placing said limestone material in contact with a solution including at least one organic solvent, water and at least one acid, as well as to the organic molecules and/or organic minerals produced by the method. The products produced by the method can be used, for example, in therapeutic and non-therapeutic fields, in particular the agri-food, cosmetic and medical fields.
摘要翻译： 本发明涉及从石灰石材料中提取有机分子和/或有机矿物的方法，包括将所述石灰石材料与包含至少一种有机溶剂，水和至少一种酸的溶液接触， 有机分子和/或通过该方法生产的有机矿物。 通过该方法制备的产品可用于例如治疗和非治疗领域，特别是农业食品，化妆品和医疗领域。
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公开(公告)号：US20060105689A1
公开(公告)日：2006-05-18
申请号：US10542912
申请日：2004-02-03
申请人： Evelyne Lopez , Marthe Rousseau
发明人： Evelyne Lopez , Marthe Rousseau
IPC分类号： A22C29/02
摘要： The method of extracting a lipidic active principle from a solid material coming from a nacreous mollusk comprises the steps of grinding the nacre into a fine powder, preferably having a mean grain size of less than 20 μm, of putting the powder into contact with a lipid solvent, of separating the solvent, and of extracting the lipidic active principle by evaporating the solvent.
摘要翻译： 从珍珠软体动物的固体材料提取脂质活性成分的方法包括以下步骤：将珍珠粉研磨成细粉末，优选平均粒径小于20μm，将粉末与脂质接触 溶剂，分离溶剂，以及通过蒸发溶剂提取脂质活性成分。
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公开(公告)号：US07238098B2
公开(公告)日：2007-07-03
申请号：US10542912
申请日：2004-02-03
申请人： Evelyne Lopez , Marthe Rousseau
发明人： Evelyne Lopez , Marthe Rousseau
IPC分类号： A22C29/02
摘要： The method of extracting a lipidic active principle from a solid material coming from a nacreous mollusk comprises the steps of grinding the nacre into a fine powder, preferably having a mean grain size of less than 20 μm, of putting the powder into contact with a lipid solvent, of separating the solvent, and of extracting the lipidic active principle by evaporating the solvent.
摘要翻译： 从珍珠软体动物的固体材料提取脂质活性成分的方法包括以下步骤：将珍珠粉研磨成细粉末，优选平均粒径小于20μm，将粉末与脂质接触 溶剂，分离溶剂，以及通过蒸发溶剂提取脂质活性成分。
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5.发明授权Method for preparing a composition by extraction of mother-of-pearl, composition obtained by said method and use thereof in cosmetics and dermatology 失效通过提取珍珠母制备组合物的方法，通过所述方法获得的组合物及其在化妆品和皮肤病学中的用途公开(公告)号：US06936280B1
公开(公告)日：2005-08-30
申请号：US10089982
申请日：2000-10-05
IPC分类号： A61K8/19 , A61K8/00 , A61K8/20 , A61K8/23 , A61K8/65 , A61K8/73 , A61K8/96 , A61K8/98 , A61K9/14 , A61K31/74 , A61K33/04 , A61K33/06 , A61K33/10 , A61K33/14 , A61K33/30 , A61K35/56 , A61K35/618 , A61K47/00 , A61P17/00 , A61Q19/00 , A01N25/00
CPC分类号： A61K8/735 , A61K8/65 , A61K8/987 , A61K35/618 , A61K2800/412 , A61K2800/436 , A61Q19/00 , Y10S514/951
摘要： A method for preparing a composition, comprising a) reducing mother-of-pearl into powder with grain size distribution ranging between about 1 and about 300 μm; b) placing the obtained powder in close contact with an extracting agent in the form of a hydroglycol solution of at least a collagen, of at least a proteoglycan or a mixture thereof; then c) in collecting the extraction mixture, formed by the close contact, constituting the desired composition. The composition obtainable by said method has very interesting properties relative to the skin and/or skin appendages, in particular tissue-regenerating properties, enabling for instance improved wound healing, and anti-ageing properties for preventing and/or visibly reducing effects related to skin and/or skin appendage ageing.
摘要翻译： 一种制备组合物的方法，包括a）将珍珠母变成粉末，其粒度分布范围在约1至约300μm之间; b）将获得的粉末以至少一种胶原蛋白，至少一种蛋白聚糖或其混合物的水溶液形式的萃取剂紧密接触; 然后c）收集由紧密接触形成的提取混合物，构成所需组成。 通过所述方法可获得的组合物相对于皮肤和/或皮肤附件，特别是组织再生性质具有非常有趣的性质，例如改善伤口愈合，以及用于预防和/或显着降低与皮肤相关的作用的抗老化性质 和/或皮肤附着物老化。
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6.发明授权Method of preparing active substances from nacre, products obtained which can be used in particular as medicaments 失效从珍珠质制备活性物质的方法，可以特别用作药物获得的产品公开(公告)号：US06251438B1
公开(公告)日：2001-06-26
申请号：US09091989
申请日：1998-10-16
IPC分类号： A61K3556
CPC分类号： A61K35/618 , A61K38/00 , C07K14/43504
摘要： This invention relates to a method for preparation of biologically active substances and has the following characteristic features: (a) nacre is reduced to a powder whose grain size is less than approximately 200 &mgr;m; (b) it is placed in close contact with an aqueous solvent, (c) at the end of the contact period, the insoluble fraction is separated out to give the aqueous fraction; (d) the solvent of the aqueous fraction is concentrated to separate out the soluble or water-transportable fraction of the nacre, which is made up of biologically active substances with essentially no mineral components. The invention likewise relates to the products obtained by this method, their use for medicinal purposes and the compositions containing them.
摘要翻译： 本发明涉及一种制备生物活性物质的方法，具有以下特征：（a）将珍珠粉还原成粒度小于约200μm的粉末; （b）将其与水性溶剂紧密接触，（c）在接触期结束时，将不溶部分分离出来，得到含水部分; （d）浓缩含水部分的溶剂以分离珍珠质的可溶性或水分输送部分，其由基本上不含矿物组分的生物活性物质组成。 本发明同样涉及通过该方法获得的产品，其用于药用目的和含有它们的组合物。
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