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公开(公告)号：US11696827B2
公开(公告)日：2023-07-11
申请号：US17455207
申请日：2021-11-16
Applicant: Edwards Lifesciences Corporation
Inventor： Christopher J. Olson , Glen T. Rabito , Dustin P. Armer , Minh T. Ma , Devin H. Marr , Cheng-Tung Huang , Hiroshi Okabe , Kevin M. Stewart , Alison S. Curtis , Philip P. Corso, Jr.
IPC: A61F2/24
CPC classification number: A61F2/2439 , A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2427 , A61F2220/005 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2250/006
Abstract: Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. In embodiments, a prosthetic heart valve assembly, including a self-expandable support structure and a self-expanding heart valve, are advanced through the aortic arch of a patient using a delivery system. The support structure, which includes a plurality leaflet retaining arms, is at least partially expanded and positioned on or adjacent to the outflow side of the aortic valve. The prosthetic heart valve is positioned in the aortic valve. The prosthetic heart valve is expanded while it is within an interior of the support structure and while the support structure is positioned on or adjacent to the outflow side of the aortic valve, thereby causing one or more native leaflets of the aortic valve to be frictionally secured between the arms of the support structure and the expanded prosthetic heart valve.
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公开(公告)号：US10653862B2
公开(公告)日：2020-05-19
申请号：US15796436
申请日：2017-10-27
Applicant: Edwards Lifesciences Corporation
Inventor： Matthew T. Winston , Christopher J. Olson , Asher L. Metchik , Tri D. Tran , Alexander J. Siegel
Abstract: A delivery apparatus includes a steerable shaft having a proximal portion, a distal portion, and a pull-wire conduit that extends through the proximal and distal portions. A pull wire extends through the conduit and has a distal portion that is fixed to the shaft. An adjustment mechanism is connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the shaft. The distal portion of the shaft has a steerable portion including one or more layers. A compression-resistance portion is incorporated into a layer of the steerable portion, and extends angularly along a portion of a cross-section of the layer. The layer of the steerable portion into which the compression-resistance portion is incorporated has a first hardness, and the compression-resistance portion has a second hardness that is greater than the first hardness.
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公开(公告)号：US10517726B2
公开(公告)日：2019-12-31
申请号：US15154578
申请日：2016-05-13
Applicant: Edwards Lifesciences Corporation
Inventor： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Dixon
IPC: A61F2/24
Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion, wherein the prosthetic device is movable between a compressed configuration, in which the spacer body portion is radially compressed and is axially spaced relative to the anchor portion, and an expanded configuration, in which the spacer body portion expands radially outwardly relative to the compressed configuration and overlaps at least a portion of the anchor portion.
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公开(公告)号：US20190069994A1
公开(公告)日：2019-03-07
申请号：US16181858
申请日：2018-11-06
Applicant: Edwards Lifesciences Corporation
Inventor： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel , Stanton J. Rowe , Alison S. Curtis
IPC: A61F2/24
Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
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公开(公告)号：US12156813B2
公开(公告)日：2024-12-03
申请号：US18063510
申请日：2022-12-08
Applicant: Edwards Lifesciences Corporation
Inventor： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel , Stanton J. Rowe , Alison S. Curtis
Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In some implementations, a heart valve leaflet clipping mechanism includes a delivery apparatus and clipping arms. The clipping arms are coupled to the delivery apparatus. The clipping arms are movable between an open position and a closed position. The two clipping arms are biased to the closed position. The delivery apparatus is configured to hold the clipping arms in the open position. The delivery apparatus is configured to allow the clipping arms to move to the closed position to engage native heart valve leaflet tissue.
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Patent Agency Ranking
公开(公告)号：US11337810B2
公开(公告)日：2022-05-24
申请号：US16181858
申请日：2018-11-06
Applicant: Edwards Lifesciences Corporation
Inventor： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel , Stanton J. Rowe , Alison S. Curtis
Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.
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公开(公告)号：US20170209265A1
公开(公告)日：2017-07-27
申请号：US15482555
申请日：2017-04-07
Applicant: Edwards Lifesciences Corporation
Inventor： Emil Karapetian , Maria Charles Vija Stanislaus , Gregory Bak-Boychuk , Christopher J. Olson , Cristobal R. Hernandez , William C. Brunnett , Netanel Benichou , Lauren R. Freschauf , Alexander J. Siegel
CPC classification number: A61F2/246 , A61F2/07 , A61F2/2409 , A61F2/2418 , A61F2/2436 , A61F2/2454 , A61F2/2466 , A61F2/88 , A61F2/91 , A61F2/958 , A61F2002/077 , A61F2002/825 , A61F2210/0061 , A61F2220/0016 , A61F2230/001 , A61F2230/0065 , A61F2230/0091 , A61F2250/0004 , A61F2250/0063
Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts. The support frame further comprises one or more leaflet-engaging mechanisms configured to engage leaflets of the heart valve. The support frame can be radially expandable and collapsible.
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公开(公告)号：US12178973B2
公开(公告)日：2024-12-31
申请号：US17992427
申请日：2022-11-22
Applicant: Edwards Lifesciences Corporation
Inventor： Matthew T. Winston , Christopher J. Olson , Asher L. Metchik , Tri D. Tran , Alexander J. Siegel
Abstract: A delivery apparatus includes a steerable guide sheath. The steerable guide sheath has a steerable portion, a pull ring located in the distal portion, and a pull wire coupled at one end to the pull ring and coupled at the opposite end to a control handle. The pull wire extends longitudinally through a pull-wire conduit. The steerable guide sheath further includes a compression-resistance portion made of metal and located in the distal portion.
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公开(公告)号：US20240261098A1
公开(公告)日：2024-08-08
申请号：US18625047
申请日：2024-04-02
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Christopher J. Olson , Glen T. Rabito , Dustin P. Armer , Minh T. Ma , Devin H. Marr , Cheng-Tung Huang , Hiroshi Okabe , Kevin M. Stewart , Alison S. Curtis , Philip P. Corso, JR.
IPC: A61F2/24
CPC classification number: A61F2/2439 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2427 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2230/0076 , A61F2250/006
Abstract: Prosthetic heart valve assemblies and methods, apparatus, and systems used to deliver a prosthetic heart valve assembly. A prosthetic heart valve assembly includes an inner frame, a prosthetic leaflet section disposed within the inner frame extending between in inflow row of cells and an outflow row of cells of the inner frame, and an outer support stent. The inner frame is disposed within the outer support stent, and the outer support stent is coupled and/or fastened to the inner frame. The outer support stent includes a plurality leaflet capturing arms for capturing native leaflets between the leaflet capturing arms and a portion of the prosthetic heart valve assembly when the prosthetic heart valve assembly is implanted in a native valve. For example, the native leaflets can be frictionally secured between the leaflet capturing arms of the support stent and the inner frame.
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公开(公告)号：US11793642B2
公开(公告)日：2023-10-24
申请号：US16522600
申请日：2019-07-25
Applicant: Edwards Lifesciences Corporation
Inventor： Mark Chau , David M. Taylor , Alexander J. Siegel , Christopher J. Olson , Sergio Delgado , Alexander H. Cooper , Lauren R. Freschauf , Asher L. Metchik , Matthew T. Winston , Cristobal R. Hernandez , Emil Karapetian , Bao Khuu , Eric Robert Dixon
IPC: A61F2/24
CPC classification number: A61F2/246 , A61F2/2454 , A61F2/2463 , A61F2/2466 , A61F2220/0016 , A61F2310/00023
Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.
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