公开(公告)号：US20240398559A1

公开(公告)日：2024-12-05

申请号：US18803359

申请日：2024-08-13

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Waina Michelle Chu ,  Jian Lin Phan ,  Eric Michael Oberwise ,  Sergio Delgado ,  Lauren R. Freschauf ,  Wen Yan Chen

IPC: A61F2/24

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. In some examples, a plurality of sutures is employed to secure frame portions of the implantable device to a connector of the implantable device. Each of the sutures can be passed through one or more eyelets of the frame portions and the connector. In some examples, an implantable device includes an actuation cap having a flexible portion or a biasing element positioned between an end portion of the actuation cap and an anchor portion of the implantable device. The flexible portion or the biasing element flex or compress responsive to forces between the connector and the actuation cap.

公开(公告)号：US20240074861A1

公开(公告)日：2024-03-07

申请号：US18509257

申请日：2023-11-14

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Asher L. Metchik ,  Sergio Delgado ,  Alexander J. Siegel ,  Eric Robert Dixon ,  Lauren R. Freschauf ,  Matthew T. Winston ,  Gregory Scott Tyler, II

IPC: A61F2/24

CPC classification number: A61F2/2463 ,  A61F2/2457 ,  A61F2/2466 ,  A61F2210/0014

Abstract: A valve repair system for repairing a native valve of a patient during a non-open-heart procedure includes a delivery device and a valve repair device. The valve repair device include a pair of paddles, first gripping member, a second gripping member, and a spacer. First and second gripping member controls or first and second gripping member control portions are coupled to the first and second gripping members to move the gripping members. The spacer element is configured to close a gap in the native valve of the patient when the valve repair device is attached to the native valve.

公开(公告)号：US20230363910A1

公开(公告)日：2023-11-16

申请号：US18359833

申请日：2023-07-26

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Lauren R. Freschauf ,  Ralph Schneider

IPC: A61F2/24 ,  A61B17/122 ,  A61B17/08

CPC classification number: A61F2/246 ,  A61B17/122 ,  A61B17/083 ,  A61B17/1227 ,  A61B2017/00243

Abstract: Embodiments of valve repair systems, leaflet clip devices, and methods of reducing regurgitation through a native heart valve are disclosed. A valve repair system can include a delivery apparatus and a leaflet clip device that is coupled to the delivery apparatus. The leaflet clip device can comprise an elongated clipping member, and a tensioning mechanism. One or more tensioning members are operatively connected to the tensioning mechanism to transform the clipping member from a delivery configuration to an implantation configuration. The one or more tensioning members can include a first tensioning member having a distal end portion that is connected to a first end portion of the clipping member and a second tensioning member having a distal end portion that is connected to a second end portion of the clipping member.

公开(公告)号：US11793642B2

公开(公告)日：2023-10-24

申请号：US16522600

申请日：2019-07-25

Applicant: Edwards Lifesciences Corporation

Inventor： Mark Chau ,  David M. Taylor ,  Alexander J. Siegel ,  Christopher J. Olson ,  Sergio Delgado ,  Alexander H. Cooper ,  Lauren R. Freschauf ,  Asher L. Metchik ,  Matthew T. Winston ,  Cristobal R. Hernandez ,  Emil Karapetian ,  Bao Khuu ,  Eric Robert Dixon

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2454 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2220/0016 ,  A61F2310/00023

Abstract: In one representative embodiment, an implantable prosthetic device comprises a spacer body portion configured to be disposed between native leaflets of a heart, and an anchor portion configured to secure the native leaflets against the spacer body portion. The prosthetic device can be movable between multiple configurations. The spacer body can be made from braided, self-expandable metallic thread. A delivery apparatus can have a first shaft and a second shaft, wherein movement of the first shaft relative to the second shaft moves the anchor portion relative to the spacer body.

公开(公告)号：US20230190469A1

公开(公告)日：2023-06-22

申请号：US18172806

申请日：2023-02-22

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Emil Karapetian ,  Maria Charles Vija Stanislaus ,  Gregory Bak-Boychuk ,  Christopher J. Olson ,  Cristobal R. Hernandez ,  William C. Brunnett ,  Netanel Benichou ,  Lauren R. Freschauf ,  Alexander J. Siegel ,  Stanton J. Rowe ,  Alison S. Curtis

IPC: A61F2/24 ,  A61F2/88 ,  A61F2/07

CPC classification number: A61F2/246 ,  A61F2/2466 ,  A61F2/2409 ,  A61F2/88 ,  A61F2/07 ,  A61F2/2436 ,  A61F2/2454 ,  A61F2/2427 ,  A61F2/2418 ,  A61F2002/825

Abstract: This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises a main body formed by formed by a plurality of inner members forming an inner clover and a plurality of outer members forming an outer clover. The support frame can include gaps located between inner members of the plurality of inner members and outer members of the plurality of outer members. The inner clover can be radially inside the outer clover, and the outer clover can have larger dimensions than the inner clover. The support frames herein can be radially expandable and collapsible.

公开(公告)号：US11602431B2

公开(公告)日：2023-03-14

申请号：US16171202

申请日：2018-10-25

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Eric Robert Dixon ,  David M. Taylor ,  Asher L. Metchik ,  Matthew T. Winston ,  Gregory Scott Tyler, II ,  Lauren R. Freschauf ,  Alexander J. Siegel

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

Abstract: An exemplary valve repair device for repairing a native valve of a patient includes a coaption element, a pair of paddles, and barb portions. The barb portions extend directly from at least one of the coaption element and the pair of paddles.

公开(公告)号：US20220117729A1

公开(公告)日：2022-04-21

申请号：US17558395

申请日：2021-12-21

Applicant: Edwards Lifesciences Corporation

Inventor： Lauren R. Freschauf ,  Sergio Delgado

IPC: A61F2/24

Abstract: A valve repair device for repairing a native heart valve of a patient includes a pair of clasps, a pair of paddles, and a coupler. The clasps and paddles are configured to attach to native valve leaflets of the heart valve. The coupler is mechanically connected to the paddles. The coupler is configured to move the paddles between a partially open position and a closed position. The coupler is configured to move freely such that ends of the pair of paddles move away from one another when the native valve leaflets open during a diastolic phase of a cardiac cycle and the ends of the pair of paddles move toward one another when the native valve leaflets close during a ventricular systole of the cardiac cycle.

公开(公告)号：US20210154005A1

公开(公告)日：2021-05-27

申请号：US17169377

申请日：2021-02-05

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: A valve repair device for repairing a native valve of a patient. The valve repair device includes a compressible spacer element, a pair of paddles, and a pair of gripping members. The pair of paddles are coupled to the spacer element. The pair of gripping members are disposed between the pair of paddles. The paddles and the gripping members are configured to attach to leaflets of a heart valve.

公开(公告)号：US10959847B2

公开(公告)日：2021-03-30

申请号：US16056241

申请日：2018-08-06

Applicant: Edwards Lifesciences Corporation

Inventor： Asher L. Metchik ,  Gregory Scott Tyler, II ,  Matthew T. Winston ,  Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Alexander J. Siegel

IPC: A61F2/24

Abstract: A system for implanting a repair device onto a native valve of a natural heart to repair the native valve of a patient during a non-open-heart procedure. The system includes a base assembly having a plurality of pivoting links, a pair of paddles attached to the base assembly, a pair of gripping members attached to the base assembly, and at least one coaptation or spacer element disposed between the pair of gripping members. Movement of the pivoting links of the base assembly causes the paddles to move between an open position and a closed position. The paddles and the gripping members are configured to attach to valve leaflets of the patient. The coaptation or spacer element is configured to fill at least a portion of a gap between the valve leaflets of the patient.

公开(公告)号：US20200038180A1

公开(公告)日：2020-02-06

申请号：US16597460

申请日：2019-10-09

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba ,  Seung-Beom Yi ,  Lauren R. Freschauf ,  Juan Valencia

IPC: A61F2/24 ,  A61B17/00

Abstract: A prosthetic valve assembly includes a support structure and a valve component. The support structure includes a first frame and a sealing member. The first frame includes a lumen extending between inflow and outflow ends. The sealing member extends inwardly into the lumen of the first frame and includes a first end wall defining a first orifice, a second end wall axially spaced from the first end wall and defining a second orifice, and an inner sleeve extending axially from the first end wall to the second end wall and spaced radially inwardly from the first frame. The valve component includes a second frame and a valve structure supported inside of the second frame for permitting blood flow through the valve component in one direction and blocking blood flow in the opposite direction. The valve component is configured to expand within and engage the inner sleeve of the sealing member.