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    Bicyclic triazole α4 integrin inhibitors
    3.
    发明授权
    Bicyclic triazole α4 integrin inhibitors 失效
    双环三唑α4整联蛋白抑制剂

    公开(公告)号：US07618983B2

    公开(公告)日：2009-11-17

    申请号：US11269369

    申请日：2005-11-08

    申请人： Edward Lawson ,  Bruce Maryanoff

    发明人： Edward Lawson ,  Bruce Maryanoff

    IPC分类号： A61K31/4745 ,  A61K31/4196 ,  C07D487/02

    CPC分类号： C07D471/04 ,  C07D487/04

    摘要： The compounds of the present invention are novel bicyclic triazole amino acid-derivatives useful as α4 integrin receptor antagonists. The invention is further directed to methods for treating integrin mediated disorders including, but not limited to, inflammatory, autoimmune and cell-proliferative disorders, methods for preparing the compounds and methods for preparing the intermediates, derivatives and pharmaceutical compositions thereof.

    摘要翻译： 本发明的化合物是用作α4整联蛋白受体拮抗剂的新型双环三唑氨基酸衍生物。 本发明进一步涉及用于治疗整联蛋白介导的病症的方法，包括但不限于炎症，自身免疫和细胞增殖性疾病，制备化合物的方法及其制备方法，其衍生物和药物组合物。

    Method and apparatus for generating lift
    5.
    发明申请
    Method and apparatus for generating lift 有权
    升降机的方法和装置

    公开(公告)号：US20070252032A1

    公开(公告)日：2007-11-01

    申请号：US11224404

    申请日：2005-09-12

    申请人： Edward Lawson ,  David Boyer

    发明人： Edward Lawson ,  David Boyer

    IPC分类号： B64C15/02 ,  B64C29/00

    CPC分类号： B64C29/0016 ,  B64C15/02 ,  B64C15/14 ,  B64C29/0066 ,  B64D27/20 ,  B64D33/02 ,  B64D33/04 ,  F02C6/00 ,  F02K3/077

    摘要： A method of generating lift for a vehicle including a gas turbine engine having a combustor, a core flow heated by the combustor, and a bypass flow which bypasses the combustor. The method includes segregating at least a portion of the core flow from the bypass flow, directing the segregated portion of the core flow in a first direction to generate lift for the vehicle, segregating at least a portion of the bypass flow from the core flow, and directing the segregated a portion of the bypass flow in a second direction to generate lift for the vehicle.

    摘要翻译： 一种产生用于车辆的升降机的方法，包括具有燃烧器的燃气涡轮发动机，由燃烧器加热的芯流，以及绕过燃烧器的旁路。 该方法包括将来自旁路流的核心流的至少一部分分离，将核心流的分离部分沿第一方向引导以产生用于车辆的升力，将旁路流的至少一部分与核心流隔离， 并且将旁路流的一部分分离在第二方向上以产生用于车辆的升力。

    Method and apparatus for generating lift
    6.
    发明申请
    Method and apparatus for generating lift 有权
    升降机的方法和装置

    公开(公告)号：US20070069066A1

    公开(公告)日：2007-03-29

    申请号：US11238347

    申请日：2005-09-29

    申请人： Edward Lawson ,  Christopher Droney ,  Darold Cummings

    发明人： Edward Lawson ,  Christopher Droney ,  Darold Cummings

    IPC分类号： B64C29/00

    CPC分类号： B64C9/18 ,  B64C9/38 ,  B64C2230/04 ,  Y02T50/166 ,  Y02T50/44

    摘要： A method of generating lift for a vehicle including heating a flow of gas using a gas generator mounted on the vehicle that contributes no more than about ten percent of thrust used to propel the vehicle in a forward direction, and driving a lift fan using the heated gas flow to generate lift for the vehicle.

    摘要翻译： 一种用于产生车辆升降机的方法，包括使用安装在车辆上的气体发生器来加热气体流，所述气体发生器不仅贡献不超过用于向前推动车辆的推力的大约百分之十，并且使用加热的 气流产生车辆升力。

    Universal convergent nozzle and distinct nozzle aperture
    7.
    发明授权
    Universal convergent nozzle and distinct nozzle aperture 有权
    通用会聚喷嘴和不同的喷嘴孔

    公开(公告)号：US08317129B1

    公开(公告)日：2012-11-27

    申请号：US12410828

    申请日：2009-03-25

    申请人： Edward Lawson ,  Aaron J. Kutzmann

    发明人： Edward Lawson ,  Aaron J. Kutzmann

    IPC分类号： B64B1/24

    CPC分类号： B64D27/18 ,  B64C2039/105 ,  B64D33/04 ,  F02K1/00 ,  F05D2250/323 ,  Y02T50/12 ,  Y02T50/44 ,  Y02T50/672

    摘要： Apparatus and methods provide for an engine nozzle having a universal convergent nozzle and a distinct nozzle aperture. Aspects of the disclosure provide a universal convergent nozzle that includes a nozzle throat and is attachable at a first end to an aircraft engine and at a second end to a distinct nozzle aperture. While the distinct nozzle aperture may include features that are specific to the corresponding engine mounting location, the universal convergent nozzle may be interchangeably used with any engine and distinct nozzle aperture at any engine mounting location. The configuration of the universal convergent nozzle ensures consistent engine performance and engine exhaust plume conditioning across all engine mounting locations, irrespective of the distinct nozzle aperture features downstream of the universal convergent nozzle.

    摘要翻译： 装置和方法提供了具有通用会聚喷嘴和不同喷嘴孔的发动机喷嘴。 本公开的方面提供了一种通用会聚喷嘴，其包括喷嘴喉部，并且可在第一端附接到飞行器发动机，并且在第二端附接到不同的喷嘴孔。 虽然不同的喷嘴孔口可以包括特定于相应的发动机安装位置的特征，但是在任何发动机安装位置处，通用会聚喷嘴可以与任何发动机和不同的喷嘴孔口互换使用。 通用会聚喷嘴的配置确保了所有发动机安装位置的引擎性能和发动机排气羽流调节，而不管通用会聚喷嘴下游具有不同的喷嘴孔特征。

    Keyless entry mechanism
    9.
    发明授权
    Keyless entry mechanism 失效
    无钥匙进入机制

    公开(公告)号：US5943888A

    公开(公告)日：1999-08-31

    申请号：US990975

    申请日：1997-12-15

    申请人： Edward Lawson

    发明人： Edward Lawson

    IPC分类号： E05B47/00 ,  E05B63/24 ,  G07C9/00 ,  E05B49/00

    CPC分类号： E05B63/248 ,  E05B47/00 ,  E05B47/0046 ,  G07C2009/00769 ,  Y10T292/18 ,  Y10T292/696 ,  Y10T70/7102 ,  Y10T70/8838

    摘要： A keyless entry mechanism for opening a lock, generally comprising a housing, an operating shaft positioned within said housing and operably aligned to extend out of said housing to contact a bolt of the lock, a shaft drive positioned within said housing and operably connected to said operating shaft to extend said operating shaft, and an actuation mechanism operationally positioned within said housing for extending said shaft. The operating shaft is manually retracted and latched against the shaft drive. Upon receiving an actuation signal, the actuation mechanism releases the latched shaft drive allowing it to extend against the bolt and push the bolt into the door. The keyless mechanism simultaneously unlocks and unlatches the door.

    摘要翻译： 一种用于打开通常包括壳体的锁的无钥匙进入机构，位于所述壳体内的操作轴，并且可操作地对齐以延伸出所述壳体以伸出所述壳体的螺栓，所述轴驱动器定位在所述壳体内并可操作地连接到所述壳体 操作轴以延伸所述操作轴以及可操作地定位在所述壳体内的致动机构，用于延伸所述轴。 操作轴手动收回并锁定在轴驱动器上。 在接收到致动信号时，致动机构释放锁定轴驱动器，使其能够抵靠螺栓延伸并将螺栓推入门中。 无钥匙机构同时解锁和解锁门。