公开(公告)号：US20240360116A1

公开(公告)日：2024-10-31

申请号：US18255134

申请日：2021-12-03

Applicant: ELANCO TIERGESUNDHEIT AG

Inventor： Francois PAUTRAT ,  Chouaib TAHTAOUI ,  Pierre DUCRAY ,  Denise RAGEOT

IPC: C07D413/14 ,  A61K31/4709 ,  A61K31/538 ,  A61K31/541 ,  A61K31/69 ,  A61P33/10 ,  C07D265/36 ,  C07D413/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/107 ,  C07F5/02

CPC classification number: C07D413/14 ,  A61K31/4709 ,  A61K31/538 ,  A61K31/541 ,  A61K31/69 ,  A61P33/10 ,  C07D265/36 ,  C07D413/12 ,  C07D417/14 ,  C07D471/04 ,  C07D491/107 ,  C07F5/02

Abstract: The present invention provides compounds of formula (I′):




which are useful in the control of endoparasites, for example heartworms, in warm-blooded animals.

公开(公告)号：US20230355566A1

公开(公告)日：2023-11-09

申请号：US17786438

申请日：2020-12-17

Applicant: Elanco Tiergesundheit AG

Inventor： Peter ROLFE ,  Sarah GEORGE ,  Chouaib TAHTAOUI

IPC: A61K31/277 ,  A61K31/167 ,  A61P33/10

CPC classification number: A61K31/277 ,  A61K31/167 ,  A61P33/10

Abstract: The present invention provides a method of treating liver fluke infections in a mammal in need of such treatment comprising administering an effective amount of diamphenethide in combination with an effective amount of closantel.

公开(公告)号：US20220242857A1

公开(公告)日：2022-08-04

申请号：US17616436

申请日：2020-06-05

Applicant: Elanco Tiergesundheit AG

Inventor： Pierre DUCRAY ,  Francois PAUTRAT ,  Denise RAGEOT ,  Chouaib TAHTAOUI

IPC: C07D413/12 ,  A61P33/10 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D491/107

Abstract: The present invention provides compounds of formula (I): which are useful in the control of endoparasites, for example heartworms, in warm-blooded animals.

公开(公告)号：US20240173275A1

公开(公告)日：2024-05-30

申请号：US18431308

申请日：2024-02-02

Applicant: Elanco Tiergesundheit AG

Inventor： Sarah GEORGE ,  Peter ROLFE ,  Chouaib TAHTAOUI

IPC: A61K31/167 ,  A61K31/63 ,  A61P33/10

CPC classification number: A61K31/167 ,  A61K31/63 ,  A61P33/10

Abstract: The present invention provides a method of treating liver fluke infections in a mammal in need of such treatment comprising administering an effective amount of diamphenethide in combination with an effective amount of clorsulon.

公开(公告)号：US20240059680A1

公开(公告)日：2024-02-22

申请号：US18253061

申请日：2021-11-17

Applicant: ELANCO TIERGESUNDHEIT AG

Inventor： Nils GRIEBENOW ,  Chouaib TAHTAOUI ,  Pierre DUCRAY ,  Denise RAGEOT

IPC: C07D413/12 ,  C07D495/04 ,  C07D487/04 ,  C07D471/04 ,  C07D513/04 ,  A61P33/10

CPC classification number: C07D413/12 ,  C07D495/04 ,  C07D487/04 ,  C07D471/04 ,  C07D513/04 ,  A61P33/10

Abstract: The present invention provides compounds of formula (I):




which are useful in the control of endoparasites, for example heartworms, in warm-blooded animals.