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1.发明授权公开(公告)号：US08506530B2
公开(公告)日：2013-08-13
申请号：US11897299
申请日：2007-08-29
IPC分类号： A61M5/00
CPC分类号： A61B17/205 , A61B2090/037 , A61M37/0015 , A61M2037/003 , A61M2037/0046 , A61M2037/0053
摘要： An array for placement on the skin of a human or animal patient for the purpose of the transdermal application of pharmaceuticals, toxins or active agents, having microneedles that are situated on a carrier substrate, the microneedles having a preset breaking point in the area of the transition to the carrier substrate.
摘要翻译： 用于放置在人或动物患者的皮肤上的阵列，用于透皮施用具有位于载体基底上的微针的药物，毒素或活性剂的目的，微针在该区域中具有预设的断点 过渡到载体基底。
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2.发明申请FILLING DEVICE HAVING COOLING AND SYSTEM FOR ADMINISTERING A LIQUID MEDICATION 有权具有冷却的填充装置和用于管理液体药物的系统公开(公告)号：US20110023997A1
公开(公告)日：2011-02-03
申请号：US12734466
申请日：2008-11-17
申请人： Dick Scholten , Michael Stumber
发明人： Dick Scholten , Michael Stumber
IPC分类号： B65B3/04
CPC分类号： A61M5/44 , A61M5/001 , A61M5/1782 , A61M5/204 , A61M2005/14268 , A61M2205/123 , A61M2205/3606 , A61M2209/045 , A61M2209/086
摘要： A system having a medication reservoir for a medication dosing apparatus for administering a liquid medication, and having a medication supply container holding the liquid medication, wherein a filling device is also provided for the automatic filling of the medication reservoir with the medication coming from the medication supply container. This system for administering a medication has the advantage that reliable and simple filling of the medication may be performed.
摘要翻译： 一种具有用于给药液体药物的药物计量装置的药物储存器的系统，并且具有容纳液体药物的药物供应容器，其中还提供了一种填充装置，用于使用来自药物的药物自动填充药物储存器 供应容器 用于施用药物的该系统具有可以执行药物的可靠且简单的填充的优点。
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3.发明申请Device for storing and transporting microneedles and a method for delivering active substances with the aid of such a device 审中-公开用于存储和运输微针的装置和借助于这种装置递送活性物质的方法公开(公告)号：US20080051723A1
公开(公告)日：2008-02-28
申请号：US11821994
申请日：2007-06-25
IPC分类号： A61M5/162
CPC分类号： B65D81/22 , A61M37/0015 , A61M2037/0023 , A61M2037/0061 , B65D85/24
摘要： A device for storing and transporting microneedles and a method for delivering active substances with the aid of such a device. In the device for storing and transporting microneedles, a reservoir is provided which contains an active substance for delivery by the microneedles and the microneedles are situated within a package forming the reservoir.
摘要翻译： 用于存储和运输微针的装置和借助于这种装置递送活性物质的方法。 在用于存放和运送微针的装置中，提供一个容纳有用于由微针输送的活性物质的储存器，并且微针位于形成贮存器的包装内。
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公开(公告)号：US20070142730A1
公开(公告)日：2007-06-21
申请号：US11639052
申请日：2006-12-13
申请人： Franz Laermer , Gerd Lorenz , Michael Stumber , Dick Scholten , Christian Maeurer , Julia Patzelt
发明人： Franz Laermer , Gerd Lorenz , Michael Stumber , Dick Scholten , Christian Maeurer , Julia Patzelt
IPC分类号： A61B5/02
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/11 , A61B5/7207 , A61B5/721
摘要： An apparatus for noninvasive blood pressure measurement having a device for measuring blood pressure values and an acceleration sensor, in particular a two- or three-axis acceleration sensor for measuring movements is provided for measuring and monitoring blood pressure. Using the movement data ascertained by the acceleration sensor, movement artifacts are calculated out of the measured blood pressure values with the aid of a signal processing system.
摘要翻译： 一种用于测量血压值的装置和加速度传感器的非侵入性血压测量装置，特别是用于测量和监测血压的二轴或三轴加速度传感器。 使用由加速度传感器确定的移动数据，借助于信号处理系统，从所测量的血压值计算运动伪影。
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5.发明授权Manufacturing method for a porous microneedle array and corresponding porous microneedle array and corresponding substrate composite 有权多孔微针阵列和相应的多孔微针阵列和相应的底物复合材料的制造方法公开(公告)号：US08986256B2
公开(公告)日：2015-03-24
申请号：US12925804
申请日：2010-10-29
申请人： Dick Scholten , Michael Stumber , Franz Laermer , Ando Feyh
发明人： Dick Scholten , Michael Stumber , Franz Laermer , Ando Feyh
CPC分类号： A61M37/0015 , A61M2037/0053 , B81B2201/055 , B81B2203/0361 , B81C1/00111 , B81C2201/0114 , B81C2201/0115 , B81C2203/0118 , B81C2203/054 , Y10T225/10 , Y10T225/12
摘要： A manufacturing method for a porous microneedle array includes: forming a plurality of porous microneedle arrays, each having at least one microneedle and a porous carrier zone lying beneath it on the face of a semiconductor substrate; forming an interlayer between a non-porous residual layer of the semiconductor substrate located on the back side of the semiconductor substrate and the carrier zone, which has greater porosity than the carrier zone; detaching the residual layer from the carrier zone by breaking up the interlayer; and separating the microneedle arrays into corresponding chips.
摘要翻译： 多孔微针阵列的制造方法包括：形成多个多孔微针阵列，每个多孔微针阵列在半导体衬底的表面上具有至少一个微针和位于其下方的多孔载体区; 在位于半导体衬底背面的半导体衬底的非多孔残留层与载体区之间形成中间层，所述载流区具有比载体区更大的孔隙率; 通过破坏夹层从载体区分离残留层; 并将微针阵列分离成相应的芯片。
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6.发明申请Manufacturing method for a porous microneedle array and corresponding porous microneedle array and corresponding substrate composite 有权多孔微针阵列和相应的多孔微针阵列和相应的底物复合材料的制造方法公开(公告)号：US20110137254A1
公开(公告)日：2011-06-09
申请号：US12925804
申请日：2010-10-29
申请人： Dick Scholten , Michael Stumber , Franz Laermer , Ando Feyh
发明人： Dick Scholten , Michael Stumber , Franz Laermer , Ando Feyh
CPC分类号： A61M37/0015 , A61M2037/0053 , B81B2201/055 , B81B2203/0361 , B81C1/00111 , B81C2201/0114 , B81C2201/0115 , B81C2203/0118 , B81C2203/054 , Y10T225/10 , Y10T225/12
摘要： A manufacturing method for a porous microneedle array includes: forming a plurality of porous microneedle arrays, each having at least one microneedle and a porous carrier zone lying beneath it on the face of a semiconductor substrate; forming an interlayer between a non-porous residual layer of the semiconductor substrate located on the back side of the semiconductor substrate and the carrier zone, which has greater porosity than the carrier zone; detaching the residual layer from the carrier zone by breaking up the interlayer; and separating the microneedle arrays into corresponding chips.
摘要翻译： 多孔微针阵列的制造方法包括：形成多个多孔微针阵列，每个多孔微针阵列在半导体衬底的表面上具有至少一个微针和位于其下方的多孔载体区; 在位于半导体衬底背面的半导体衬底的非多孔残留层与载体区之间形成中间层，所述载流区具有比载体区更大的孔隙率; 通过破坏夹层从载体区分离残留层; 并将微针阵列分离成相应的芯片。
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公开(公告)号：US20090200262A1
公开(公告)日：2009-08-13
申请号：US12227509
申请日：2007-04-27
申请人： Dick Scholten , Julia Cassemeyer , Michael Stumber , Franz Laermer , Ando Feyh , Christian Maeurer
发明人： Dick Scholten , Julia Cassemeyer , Michael Stumber , Franz Laermer , Ando Feyh , Christian Maeurer
IPC分类号： C23F1/00
CPC分类号： B81C1/00119 , A61M37/0015 , A61M2037/003 , A61M2037/0038 , A61M2037/0046 , A61M2037/0053 , B81C2201/0112 , B81C2201/0115
摘要： A method for producing porous microneedles (10) situated in an array on a silicon substrate includes: providing a silicon substrate, applying a first etching mask, patterning microneedles using a DRIE process (“deep reactive ion etching”), removing the first etching mask, at least partially porosifying the Si substrate, the porosification beginning on the front side of the Si substrate and a porous reservoir being formed.
摘要翻译： 一种位于硅衬底阵列上的多孔微针（10）的制造方法，包括：提供硅衬底，施加第一蚀刻掩模，使用DRIE工艺（“深反应离子蚀刻”）图案化微针，除去第一蚀刻掩模 至少部分地使Si衬底开孔，从Si衬底的正面开始的孔隙化和形成的多孔容器。
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公开(公告)号：US20060105449A1
公开(公告)日：2006-05-18
申请号：US11211928
申请日：2005-08-24
CPC分类号： B01L3/5085 , B01L3/5088 , B01L2300/0645 , B01L2300/0819 , G01N27/3276
摘要： A biochip for electrical, e.g., capacitive, detection of biochemical molecules has an electrode array on a substrate, the electrodes of the electrode array being each connected through the substrate to an electrically conductive contact surface via an electrical conductor. The contact surfaces are situated on the side of the substrate facing away from the electrode array and form the outermost plane of the substrate on this side.
摘要翻译： 用于电气，例如电容性检测生化分子的生物芯片在衬底上具有电极阵列，电极阵列的电极各自经由衬底连接到经由电导体的导电接触表面。 接触表面位于基板的背离电极阵列的一侧，并在该侧形成基板的最外平面。
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9.发明授权Filling device having cooling and system for administering a liquid medication 有权具有冷却的灌装装置和用于施用液体药物的系统公开(公告)号：US08839828B2
公开(公告)日：2014-09-23
申请号：US12734466
申请日：2008-11-17
申请人： Dick Scholten , Michael Stumber
发明人： Dick Scholten , Michael Stumber
CPC分类号： A61M5/44 , A61M5/001 , A61M5/1782 , A61M5/204 , A61M2005/14268 , A61M2205/123 , A61M2205/3606 , A61M2209/045 , A61M2209/086
摘要： A system having a medication reservoir for a medication dosing apparatus for administering a liquid medication, and having a medication supply container holding the liquid medication, a filling device being provided for the automatic filling of the medication reservoir with the medication coming from the medication supply container. Fluidic connections may be provided between individual components for transfer and filling of the liquid medication. This system for administering a medication has the advantage that reliable and simple filling of the medication may be performed.
摘要翻译： 一种具有用于给药液体药物的药物计量装置的药物储存器的系统，并且具有容纳液体药物的药物供应容器的装置，设置有用于从药物供应容器来的药物自动填充药物贮存器的填充装置 。 可以在各个部件之间提供流体连接以用于液体药物的转移和填充。 用于施用药物的该系统具有可以执行药物的可靠且简单的填充的优点。
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10.发明授权Method for manufacturing porous microstructures, porous microstructures manufactured according to this method, and the use thereof 失效用于制造多孔微结构的方法，根据该方法制造的多孔微结构及其用途公开(公告)号：US08377315B2
公开(公告)日：2013-02-19
申请号：US12810973
申请日：2008-11-19
申请人： Dick Scholten , Tjalf Pirk , Michael Stumber , Franz Laermer , Ralf Reichenbach , Ando Feyh
发明人： Dick Scholten , Tjalf Pirk , Michael Stumber , Franz Laermer , Ralf Reichenbach , Ando Feyh
IPC分类号： C23F1/00
CPC分类号： A61K9/0019 , A61B5/02755 , A61K9/0024 , A61K9/2009 , A61K31/337 , A61M37/0015 , A61M2037/0023 , A61M2037/0053 , B81B2201/055 , B81C1/00126 , B81C2201/0115 , Y10T428/249978
摘要： A method for manufacturing porous microstructures in a silicon semiconductor substrate, porous microstructures manufactured according to this method, and the use thereof.
摘要翻译： 一种用于制造硅半导体衬底中的多孔微结构的方法，根据该方法制造的多孔微结构及其用途。
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