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    Enhanced visualization of in-vivo breast biopsy location for medical documentation
    1.
    发明授权
    Enhanced visualization of in-vivo breast biopsy location for medical documentation 有权
    增强医学文献体内乳腺活检位置的可视化

    公开(公告)号：US06351660B1

    公开(公告)日：2002-02-26

    申请号：US09551456

    申请日：2000-04-18

    申请人： Thomas M. Burke ,  David T. Carrott

    发明人： Thomas M. Burke ,  David T. Carrott

    IPC分类号： A61M565

    CPC分类号： G06T7/0012 ,  A61B8/463 ,  A61B17/3403 ,  A61B34/10 ,  A61B90/36 ,  A61B2090/364

    摘要： An image processing system and method visually documents and displays the in-vivo location from which a biopsy specimen was extracted, by processing pre-biopsy and post-biopsy images. A composite image is created which visually emphasizes differences between the pre-biopsy and post-biopsy images. Preferably three-dimensional, digitized images, displayable in various projections, are stored for archival purposes on computer readable media. An image processor preferably exploits an optical correlator to register the pre-biopsy and post-biopsy images accurately. The images are then compared, voxel-by-voxel, to detect differences between pre-biopsy and post-biopsy images. The composite image is displayed with synthetic colors, synthetic icons, or other visual clues to emphasize probable in-vivo biopsy locations.

    摘要翻译： 图像处理系统和方法通过处理活检前和活检后图像来目视地记录和显示从中提取活检标本的体内位置。 创建复合图像，其视觉上强调活检前和活检后图像之间的差异。 优选地，可显示在各种投影中的三维数字化图像被存储用于存储在计算机可读介质上的目的。 图像处理器优选地利用光学相关器来准确地记录活检前和活检后图像。 然后将图像与体素体素进行比较，以检测活检前和活检后图像之间的差异。 复合图像以合成颜色，合成图标或其他视觉线索显示，以强调可能的体内活检位置。

    Historical comparison of breast tissue by image processing
    2.
    发明授权
    Historical comparison of breast tissue by image processing 失效
    通过图像处理对乳腺组织进行历史比较

    公开(公告)号：US06909792B1

    公开(公告)日：2005-06-21

    申请号：US09602251

    申请日：2000-06-23

    申请人： David T. Carrott ,  Thomas M. Burke

    发明人： David T. Carrott ,  Thomas M. Burke

    IPC分类号： G06K9/00 ,  G06K9/32 ,  G06T7/00

    CPC分类号： G06T7/0012 ,  G06T7/32 ,  G06T2207/30068

    摘要： An image processing system and method visually documents and displays changes between historical and later mammographic images, preferably in three dimensions. A composite image is created which visually emphasizes temporal differences between the historical and later images. Preferably three-dimensional, digitized images, displayable in various projections, are stored for archival purposes on computer readable media. An image processor preferably exploits an optical correlator to register the historical and later images accurately and provide correlation values as temporal scalars of the differences. The registered images are then compared, voxel-by-voxel, to detect temporal differences. The composite image is displayed with synthetic colors or other visual clues to emphasize apparent changes (for example, tumor growth or shrinkage).

    摘要翻译： 图像处理系统和方法可视地记录和显示历史和以后的乳房照相图像之间的改变，优选地在三维中。 创建合成图像，其视觉上强调历史和稍后图像之间的时间差异。 优选地，可显示在各种投影中的三维数字化图像被存储用于存储在计算机可读介质上的目的。 图像处理器优选地利用光相关器来准确地登记历史和后期图像，并且将相关值作为差值的时间标量提供。 然后将注册的图像与体元体素进行比较，以检测时间差异。 复合图像用合成颜色或其他视觉线索显示，以强调明显的变化（例如肿瘤生长或收缩）。

    Optical correlator assisted detection of calcifications for breast biopsy
    3.
    发明授权
    Optical correlator assisted detection of calcifications for breast biopsy 有权
    光学相关器辅助检测乳腺活检钙化

    公开(公告)号：US06421454B1

    公开(公告)日：2002-07-16

    申请号：US09521266

    申请日：2000-03-08

    申请人： Thomas M. Burke ,  David T. Carrott

    发明人： Thomas M. Burke ,  David T. Carrott

    IPC分类号： G06K900

    CPC分类号： A61B6/5247 ,  A61B6/502 ,  A61B8/0825 ,  A61B8/4416 ,  G06T7/32 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/30068

    摘要： Ultrasonographic imaging of small calcifications or similar hard bodies distributed in human breast tissue is enhanced by correlating an ultrasonographic data set with a radiographic image of the same region of interest. A “constellation” or cluster of small calcifications is distinguished from speckle noise by the cross-correlation, which is quite sensitive to the coincidence of a pattern of distributed small targets in both the ultrasonographic and radiographic images, notwithstanding the presence of random noise. An optical correlator is preferably used to perform high speed cross-correlations. The three-dimensional position of an individual calcification is preferably found by projecting from an identified point in the radiographic image, along a projection vector, to a voxel with extreme density in the ultrasonographic volumetric data set. Multiple projection vector orientations are tested for image correlation, to accomodate any probable skew between the ultrasonographic and radiographic projections.

    摘要翻译： 通过将超声波数据集与相同感兴趣区域的放射照相图像相关联来增强分布在人乳腺组织中的小钙化或类似硬体的超声成像。 一个“星座”或小钙化簇与斑驳噪声区分开来，这是互相关的，尽管存在随机噪声，但对于超声和放射照相图像中分布的小目标图案的一致性非常敏感。 光学相关器优选地用于执行高速互相关。 单个钙化的三维位置优选通过从放射线图像中的识别点沿投影矢量突出到超声波体积数据集中具有极高密度的体素而发现。 测试多个投影矢量方向的图像相关性，以适应超声和射线照相投影之间的任何可能的偏斜。

    Optical correlator based automated pathologic region of interest selector for integrated 3D ultrasound and digital mammography
    4.
    发明授权
    Optical correlator based automated pathologic region of interest selector for integrated 3D ultrasound and digital mammography 有权
    基于光学相关器的自动病理感兴趣区域选择器用于综合3D超声和数字乳腺X线摄影

    公开(公告)号：US06396940B1

    公开(公告)日：2002-05-28

    申请号：US09322129

    申请日：1999-05-27

    申请人： David T. Carrott ,  Thomas M. Burke

    发明人： David T. Carrott ,  Thomas M. Burke

    IPC分类号： G06K900

    CPC分类号： A61B8/4416 ,  A61B6/502 ,  A61B6/5247 ,  A61B8/0825 ,  G06T7/32 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/30068

    摘要： Ultrasonographic information about the internal structure of a subject body is combined with x-ray or other radiographic information from the same subject body by using an optical correlator to quickly find a transformation which aligns the information from both sources, even if they are acquired in different coordinate systems. Various spatial transformations are applied to the information and cross-correlations are quickly performed. The transformation which gives the best cross-correlation is used to align the two data sets, which can then be displayed visually. The resulting display can be used as an aid in medical diagnosis, for example in diagnosing suspected malignant lesions in a woman's breast.

    摘要翻译： 关于被摄体的内部结构的超声信息通过使用光学相关器与来自相同主体的X射线或其它放射线照相信息组合，以快速找到使来自两个源的信息对齐的变换，即使它们以不同的方式获取 坐标系。 对信息应用各种空间变换，并快速执行互相关。 提供最佳互相关的变换用于对齐两个数据集，然后可以直观地显示。 所得到的显示可以用作医学诊断的辅助，例如在诊断女性乳房中的疑似恶性病变中。

    Method of making a void-free non-cellulose electrical winding
    6.
    发明授权
    Method of making a void-free non-cellulose electrical winding 失效
    制造无空隙的非纤维素电绕组的方法

    公开(公告)号：US4554730A

    公开(公告)日：1985-11-26

    申请号：US569069

    申请日：1984-01-09

    申请人： Dean C. Westervelt ,  Thomas M. Burke

    发明人： Dean C. Westervelt ,  Thomas M. Burke

    IPC分类号： H01F27/32 ,  H01F41/04 ,  H01F41/12 ,  H01F3/06

    CPC分类号： H01F27/323 ,  H01F41/04 ,  H01F41/122 ,  Y10T29/49071

    摘要： Methods of constructing a void-free, cellulose-free electrical winding insulated with a solid resinous insulation. The method includes forming a plurality of conductor turns on a substrate, with each conductor turn being immersed in liquid resinous insulation as it is formed, to provide a void-free intermediate structure. The void-free aspect of the intermediate structure is maintained up to and including the final step of the method by building solid insulation, thin layer upon thin layer, from the liquid resinous insulation, while the conductor turns are being formed, with the solid insulation, as it is formed, providing a solid substrate for the continued application of liquid resinous insulation and subsequent conductor turns of the winding.

    摘要翻译： 用固体树脂绝缘材料构造无空隙，无纤维素的电绕组的方法。 该方法包括在基板上形成多个导体匝，每个导体匝在其形成时浸入液态树脂绝缘体中，以提供无空隙的中间结构。 中间结构的无空隙方面通过在形成导体匝的同时通过在液体树脂绝缘体上形成固体绝缘层（薄层薄层）来维持并包括该方法的最终步骤，其中固体绝缘体 ，因为它形成，为连续施加液体树脂绝缘和随后的绕组导体匝提供了坚实的基板。

    Method of highlighting subtle contrast in graphical images
    7.
    发明授权
    Method of highlighting subtle contrast in graphical images 失效
    强调图形图像微妙对比的方法

    公开(公告)号：US5042077A

    公开(公告)日：1991-08-20

    申请号：US326349

    申请日：1989-03-21

    申请人： Thomas M. Burke

    发明人： Thomas M. Burke

    IPC分类号： G01R33/54 ,  G06T5/40

    CPC分类号： G01R33/54 ,  G06T5/008 ,  G06T5/30 ,  G06T5/40 ,  G06T2207/30004

    摘要： A display for medical diagnostic equipment produces an image of the subject under study and a histogram image which indicates the distribution of brightness levels of the image pixels. Using a trackball, the operator manipulates a contrast window which is displayed on the histogram and which enables the operator to select brightness ranges in the image for contrast enhancement.

    摘要翻译： 用于医疗诊断设备的显示器产生被研究对象的图像和指示图像像素的亮度级别分布的直方图图像。 使用轨迹球，操作员操纵显示在直方图上的对比度窗口，并且使得操作者能够选择图像中的亮度范围用于对比度增强。

    Backscatter data collection technique for ultrasound
    8.
    发明授权
    Backscatter data collection technique for ultrasound 失效
    超声反向散射数据采集技术

    公开(公告)号：US4803994A

    公开(公告)日：1989-02-14

    申请号：US84228

    申请日：1987-08-12

    申请人： Thomas M. Burke

    发明人： Thomas M. Burke

    IPC分类号： G01S15/89 ,  A61B8/08 ,  A61B8/14 ,  G01S7/52 ,  A61B10/00

    CPC分类号： G01S7/52036 ,  A61B8/08

    摘要： A rapid, non-invasive realtime modality for detecting differential backscatter in ultrasound is achieved using narrowband interrogating frequencies to maximize signal-to-noise ratio and to minimize location errors. Additional improvement in signal-to-noise ratio and separation of tissue populations are achieved by cyclically alternating through a fixed number of predetermined burst lengths and by employing multiple narrowband bursts of differing fundamental frequencies.

    摘要翻译： 使用窄带询问频率来实现用于检测超声中的差分后向散射的快速，非侵入式实时模式，以使信噪比最大化并最小化位置误差。 通过以固定数量的预定突发长度循环交替并且通过采用不同基频的多个窄带脉冲串来实现信噪比和组织群体分离的附加改善。

    Self diagnostic ultrasonic imaging systems
    10.
    发明授权
    Self diagnostic ultrasonic imaging systems 失效
    自诊断超声成像系统

    公开(公告)号：US5517994A

    公开(公告)日：1996-05-21

    申请号：US340562

    申请日：1994-11-16

    申请人： Thomas M. Burke ,  James Mehi

    发明人： Thomas M. Burke ,  James Mehi

    IPC分类号： G01B17/00 ,  A61B8/00 ,  B06B1/02 ,  B06B1/06 ,  G01N29/00 ,  G01S7/52 ,  G01S7/521 ,  G01S15/89

    CPC分类号： G01S7/52079 ,  B06B1/0622 ,  G01S7/5205 ,  B06B2201/40 ,  G01S15/8918 ,  G01S15/8979 ,  G01S7/52017

    摘要： A method and apparatus are described for testing the integrity of an ultrasonic transducer probe or the ultrasound system connected to the probe. The elements of the transducer are pulsed at a time when the probe is not in contact with a patient and the surface of the probe lens is exposed to the open air. The channel electronics receives the echo signal returned from the lens-air interface and reverberations between this interface and the transducer. These signals are analyzed by a diagnostic processor coupled to the channel electronics for characteristics such as amplitude, time of echo reception, group delay, and other characteristics to determine the possible existence of problems such as faulty transducer elements or connections and problems in the system receive electronics. The diagnostic processor can adaptively adjust an operating characteristic of the system electronics such as gain or time delay to compensate for a detected out of tolerance condition.

    摘要翻译： 描述了一种用于测试超声波换能器探头或连接到探头的超声系统的完整性的方法和装置。 当探头不与患者接触并且探针透镜的表面暴露于露天时，换能器的元件被脉冲。 通道电子设备接收从透镜空中接口返回的回波信号和该接口与传感器之间的混响。 这些信号由耦合到信道电子设备的诊断处理器分析，用于诸如振幅，回波接收时间，组延迟和其它特性的特性，以确定可能存在诸如故障换能器元件或连接的问题以及系统接收中的问题 电子产品。 诊断处理器可以自适应地调整系统电子设备的操作特性，例如增益或时间延迟，以补偿检测到的超出公差状况。