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公开(公告)号：US20240424060A1
公开(公告)日：2024-12-26
申请号：US18763519
申请日：2024-07-03
Applicant: DOMPE' FARMACEUTICI SPA
Inventor： Andrea ARAMINI , Pier Giorgio AMENDOLA , Anna SIRICO , Gaetano D'ANNIBALLE , Franca CATTANI , Marcello ALLEGRETTI , Flavio MANTELLI
Abstract: The present invention relates to the field of treatment of ocular pathologies by administration of a NGF, which comprises more than 50% by weight of the NGF isoform of SEQ ID NO: 1. Said NGF is particularly useful in the treatment of ocular pathologies where the proliferation and survival effect of NGF is desired and where the proapoptotic effect of p75NTR is detrimental.
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2.发明公开公开(公告)号：US20230390156A1
公开(公告)日：2023-12-07
申请号：US18034252
申请日：2021-10-27
Applicant: Dompe' Farmaceutici SpA
Inventor： Marcello ALLEGRETTI , Lucia APPARENTE , Marco Maria GENTILE , Simone MATTIOLI
CPC classification number: A61J1/1468 , A61K38/185
Abstract: The present invention relates to a pharmaceutical package comprising a plastic container and an aqueous formulations of nerve growth factor (NGF), in which at least the surface of the container in contact with the NGF aqueous formulation is made of particular polypropylenes (PPs), characterized by certain thermal properties and crystallinity. Advantageously said containers show a NGF adhesion significantly lower than that of siliconized glass or of other polypropylenes. It is thus possible to store aqueous formulations of NGF in less severe conditions, avoiding additional coating treatments to the containers and additives while keeping the NGF titer constant.
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公开(公告)号：US20240180889A1
公开(公告)日：2024-06-06
申请号：US18284951
申请日：2022-03-31
Applicant: Dompe' farmaceutici SpA
Inventor： Marcello ALLEGRETTI , Andrea Rosario BECCARI , Maria Candida CESTA , Elisabetta Maria Ester MAURI , Carmine TALARICO
IPC: A61K31/4535 , A61K39/00 , A61K39/215
CPC classification number: A61K31/4535 , A61K39/215 , A61K2039/53
Abstract: The present invention relates to the combination of a Selective Estrogen Receptor Modulator (SERM) and a COVID-19 vaccine.
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公开(公告)号：US20240180888A1
公开(公告)日：2024-06-06
申请号：US18282357
申请日：2022-03-17
Applicant: Dompe' Farmaceutici SPA
Inventor： Marcello ALLEGRETTI , Andrea ARAMINI , Piergiorgio AMENDOLA , Laura BRANDOLINI , Maria Candida CESTA , Anna SIRICO
IPC: A61K31/451 , A61K31/427 , A61K39/00 , A61P37/08 , C07K16/28
CPC classification number: A61K31/451 , A61K31/427 , A61P37/08 , C07K16/2896 , A61K2039/505 , C07K2317/76
Abstract: The present invention relates to the use of a C5aR1 inhibitor for the prevention or treatment of a hypersensitivity reaction (HSR) to a taxane in an individual.
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Patent Agency Ranking
5.发明公开公开(公告)号：US20230357121A1
公开(公告)日：2023-11-09
申请号：US17922999
申请日：2021-05-04
Applicant: DOMPE' FARMACEUTICI SPA
Inventor： Andrea ARAMINI , Marcello ALLEGRETTI , Gianluca BIANCHINI , Samuele LILLINI , Mara TOMASSETTI
IPC: C07C59/84 , C07C229/26 , C07C229/28
CPC classification number: C07C59/84 , C07C229/26 , C07C229/28 , C07C2601/14 , C07B2200/13
Abstract: The present invention relates to a new co-crystal of Ketoprofen, Lysine and Gabapentin, to pharmaceutical compositions and to their use in the prevention, reduction or treatment of pain and/or inflammation.
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公开(公告)号：US20230090111A1
公开(公告)日：2023-03-23
申请号：US17800634
申请日：2021-02-19
Applicant: Dompe' farmaceutici SpA
Inventor： Marcello ALLEGRETTI , Pieradelchi RUFFINI
IPC: A61K31/18 , A61P43/00 , A61K31/426 , A61K9/00 , A61P35/00
Abstract: The present invention relates to a CXCL8 inhibitor and a pharmaceutical composition thereof, for use in the prevention or treatment of cancer-related fatigue in a cancer patient.
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7.发明公开公开(公告)号：US20240156757A1
公开(公告)日：2024-05-16
申请号：US18279708
申请日：2022-03-03
Applicant: DOMPE' FARMACEUTICI SPA
Inventor： Marcello ALLEGRETTI , Laura BRANDOLINI , Annamaria VEZZANI , Rossella DI SAPIA , Teresa RAVIZZA , Silvia Maria BALOSSO
Abstract: The present invention relates to a CXCL8 inhibitor and a pharmaceutical composition thereof, for use in the prevention or treatment of seizures.
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公开(公告)号：US20240091311A1
公开(公告)日：2024-03-21
申请号：US18275849
申请日：2022-02-04
Applicant: DOMPE' FARMACEUTICI SPA
Inventor： Andrea ARAMINI , Pier Giorgio AMENDOLA , Anna SIRICO , Gaetano D'ANNIBALLE , Franca CATTANI , Marcello ALLEGRETTI , Flavio MANTELLI
CPC classification number: A61K38/185 , A61P27/02
Abstract: The present invention relates to the field of treatment of ocular pathologies by administration of a NGF, which comprises more than 50% by weight of the NGF isoform of SEQ ID NO: 1. Said NGF is particularly useful in the treatment of ocular pathologies where the proliferation and survival effect of NGF is desired and where the proapoptotic effect of p75NTR is detrimental.
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公开(公告)号：US20230141355A1
公开(公告)日：2023-05-11
申请号：US17914529
申请日：2021-03-24
Applicant: Dompe' Farmaceutici SPA
Inventor： Marcello ALLEGRETTI , Flavio MANTELLI , Lorenzo PIEMONTI
IPC: A61K31/18 , A61K31/675 , A61K31/737 , A61K31/573 , A61K31/496 , A61K31/431 , A61K38/20 , A61K31/635 , A61K31/167 , A61K31/616 , A61K31/415 , A61K31/7052 , A61K31/546 , A61K31/135 , A61P31/14
CPC classification number: A61K31/18 , A61K31/675 , A61K31/737 , A61K31/573 , A61K31/496 , A61K31/431 , A61K38/2006 , A61K31/635 , A61K31/167 , A61K31/616 , A61K31/415 , A61K31/7052 , A61K31/546 , A61K31/135 , A61P31/14
Abstract: The present invention relates to CXCL8 inhibitors for use in the treatment of COVID-19 patients with pneumonia.
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