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Patent Agency Ranking
公开(公告)号：US20150004665A1
公开(公告)日：2015-01-01
申请号：US14485314
申请日：2014-09-12
Applicant: Danisco US Inc. , THE GOODYEAR TIRE & RUBBER COMPANY
Inventor： Gopal K. CHOTANI , Brian KIRSHNER , Jacob LATONE , Jeff P. PUCCI
IPC: C12P5/00
CPC classification number: C12P5/007 , C12N9/88 , C12Y402/03027
Abstract: This invention relates to methods for producing isoprene by culturing recombinant cells (e.g., cells engineered to produce isoprene) under reduced oxygen inlet levels.
Abstract translation: 本发明涉及通过在减少的氧气入口水平下培养重组细胞（例如，改造成产生异戊二烯的细胞）来生产异戊二烯的方法。
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公开(公告)号：US20180002727A1
公开(公告)日：2018-01-04
申请号：US15694193
申请日：2017-09-01
Applicant: Danisco US Inc. , The Goodyear Tire & Rubber Company
Inventor： Zachary Q. BECK , Michael C. MILLER , Caroline M. PERES , Yuliya A. PRIMAK , Jeff P. PUCCI , Derek H. WELLS
CPC classification number: C12P5/007 , C12N9/0006 , C12N9/1025 , C12N9/1029 , C12N15/70 , C12N15/81 , C12P5/002 , C12P7/02 , C12P7/04 , C12P7/42 , C12Y101/01034 , C12Y203/01016 , C12Y203/0301 , Y02E50/343
Abstract: The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, and/or isoprenoids in microorganisms via the heterologous expression of the mvaE and mvaS genes from the organisms Listeria grayi DSM 20601, Enterococcus faecium, Enterococcus gallinarum EG2, and Enterococcus casseliflavus.
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公开(公告)号：US20130164809A1
公开(公告)日：2013-06-27
申请号：US13725949
申请日：2012-12-21
Applicant: DANISCO US INC.
Inventor： Gopal K. CHOTANI , Brian KIRSHNER , Jacob LATONE , Jeff P. PUCCI
IPC: C12P5/00
CPC classification number: C12P5/007 , C12N9/88 , C12Y402/03027
Abstract: This invention relates to methods for producing isoprene by culturing recombinant cells (e.g., cells engineered to produce isoprene) under reduced oxygen inlet levels.
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4.发明申请公开(公告)号：US20190153479A1
公开(公告)日：2019-05-23
申请号：US16200485
申请日：2018-11-26
Applicant: Danisco US Inc. , The Goodyear Tire & Robber Company
Inventor： Zachary Q. BECK , Michael C. MILLER , Caroline M. PERES , Yuliya A. PRIMAK , Jeff P. PUCCI , Derek H. WELLS
IPC: C12P5/00 , C12P5/02 , C12N9/04 , C12N15/70 , C12P7/42 , C12P7/04 , C12P7/02 , C12N9/88 , C12N9/18 , C12N9/12 , C12N9/10 , C12N9/02
Abstract: The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, and/or isoprenoids in microorganisms by engineering a microorganism for increased carbon flux towards mevalonate production in the following enzymatic pathways: (a) citrate synthase, (b) phosphotransacetylase, (c) acetate kinase, (d) lactate dehydrogenase, (e) malic enzyme, and (f) pyruvate dehydrogenase such that one of more of the enzyme activity is modulated. In addition, production of mevalonate, isoprene, isoprenoid precursor molecules, and/or isoprenoids can be further enhanced by the heterologous expression of the mvaE and mvaS genes (such as, but not limited to, mvaE and mvaS genes from the organisms Listeria grayi DSM 20601, Enterococcus faecium, Enterococcus gallinarum EG2, and Enterococcus casseliflavus).
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公开(公告)号：US20150010970A1
公开(公告)日：2015-01-08
申请号：US14329466
申请日：2014-07-11
Applicant: Danisco US Inc.
Inventor： Gopal K. CHOTANI , Manoj KUMAR , Jeff P. PUCCI , Karl J. SANFORD , Jayarama K. SHETTY
CPC classification number: C12P7/56 , C12P7/06 , C12P7/10 , C12P7/18 , C12P7/20 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/58 , C12P7/60 , C12P19/02 , C12P2201/00 , Y02E50/16 , Y02E50/17
Abstract: The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate.
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