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公开(公告)号：US20240026313A1
公开(公告)日：2024-01-25
申请号：US18476753
申请日：2023-09-28
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
CPC分类号： C12N9/0071 , C07K14/80 , C12Y114/14001 , C12P13/001 , C12N9/0042 , C12Y106/02004
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US10704030B2
公开(公告)日：2020-07-07
申请号：US16562673
申请日：2019-09-06
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US20200002685A1
公开(公告)日：2020-01-02
申请号：US16562673
申请日：2019-09-06
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US10450550B2
公开(公告)日：2019-10-22
申请号：US16152709
申请日：2018-10-05
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US20220169994A1
公开(公告)日：2022-06-02
申请号：US17672542
申请日：2022-02-15
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US20210214694A1
公开(公告)日：2021-07-15
申请号：US17203421
申请日：2021-03-16
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US20170275598A1
公开(公告)日：2017-09-28
申请号：US15619176
申请日：2017-06-09
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
IPC分类号： C12N9/02
CPC分类号： C12N9/0071 , C07K14/80 , C12N9/0042 , C12P13/001 , C12Y106/02004 , C12Y114/14001
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US09708587B2
公开(公告)日：2017-07-18
申请号：US14794249
申请日：2015-07-08
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
IPC分类号： C12N9/02
CPC分类号： C12N9/0071 , C12N9/0042 , C12Y106/02004 , C12Y114/14001
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US09683220B2
公开(公告)日：2017-06-20
申请号：US15171116
申请日：2016-06-02
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
CPC分类号： C12N9/0071 , C12N1/16 , C12N1/20 , C12N9/0042 , C12N15/52 , C12N15/63 , C12Y106/02004 , C12Y114/14001
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
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公开(公告)号：US20170009213A1
公开(公告)日：2017-01-12
申请号：US15171116
申请日：2016-06-02
申请人： Codexis, Inc.
发明人： Robert Osborne , Vesna Mitchell , Khin Yu Naing Htwe , Xiyun Zhang , Erika M. Milczek , Jeffrey C. Moore
IPC分类号： C12N9/02
CPC分类号： C12N9/0071 , C12N1/16 , C12N1/20 , C12N9/0042 , C12N15/52 , C12N15/63 , C12Y106/02004 , C12Y114/14001
摘要： The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
摘要翻译： 本发明提供了改进的活性改善的P450-BM3变体。 在一些实施方案中，P450-BM3变体在宽范围的底物上表现出改善的活性。
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