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1.发明授权公开(公告)号：US11525815B2
公开(公告)日：2022-12-13
申请号：US16846454
申请日：2020-04-13
Applicant: Chenland Nutritionals, Inc.
Inventor： Shengcan Zou , Li Li , Lei Zong , Jiancheng Zong , Shanglong Wang , Zengliang Zhang
Abstract: The present invention discloses a method for product quality control and fingerprint detection of an epimedium brevicornu complex. The method uses high performance liquid chromatography, and can effectively realize the quality control of products containing traditional Chinese medicine components, and especially stable control of the quality of products containing a large quantity of non-traditional Chinese medicine components in formulas. Through step-by-step quality control, product quality fluctuation is reduced and stable quality is ensured. Meanwhile, the method is simple and convenient, does not need additional instruments and standards, saves the cost and is more conducive to actual production.
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公开(公告)号：US20220211795A1
公开(公告)日：2022-07-07
申请号：US17699200
申请日：2022-03-21
Inventor： Shengcan Zou , Shanglong Wang , Lei Zong , Jiancheng Zong , Min Han , Xin Li , Mingliang Xu
IPC: A61K36/9066 , A61K9/19 , A61K47/02 , A61K47/38
Abstract: A curcumin compound composition and method for preparing the composition is disclosed. In order to improve the dissolution and bioavailability of curcumin, the compound composition is prepared by mixing curcumin and excipients according to a ratio, and the compound composition is prepared by tightly combining curcumin with glycerol monostearate and sodium carboxymethyl cellulose. The preparation process is suitable for industrialization, and the prepared compound composition has stable properties and improves the bioavailability of curcumin, and has good application and promotion prospects.
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3.发明申请公开(公告)号：US20210069275A1
公开(公告)日：2021-03-11
申请号：US17035808
申请日：2020-09-29
Applicant: Chenland Nutritionals Inc.
Inventor： Shengcan Zou , Zengliang Zhang , Jiancheng Zong , Wenyu LI , Xin LI , Li Li , Shanglong Wang , Lei Zong
Abstract: A traditional Chinese medicine composition includes 60%-80% by weight of Eucommia ulmoides extract, 15%-30% by weight of Rhizoma Drynariae extract and 5%-10% by weight of Semen Cuscutae extract. A method of preparing the traditional Chinese medicine composition is also provided. Uses of the traditional Chinese medicine composition in the prevention and/or treatment of osteoporosis are also provided.
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公开(公告)号：US11975052B2
公开(公告)日：2024-05-07
申请号：US17156534
申请日：2021-01-23
Applicant: Chenland Nutritionals Inc. , Qingdao Chenland Pharmaceutical Technology Development Co., Ltd.
Inventor： Shengcan Zou , Zengliang Zhang , Jiancheng Zong , Wenyu Li , Xin Li , Li Li , Shanglong Wang , Lei Zong
IPC: A61K38/39 , A23J3/34 , A23L29/281 , A23L33/00 , A23L33/105 , A23L33/155 , A23L33/16 , A23L33/17 , A61K31/122 , A61K31/593 , A61K33/06 , A61K36/126 , A61K36/39 , A61K36/46 , A61P19/00
CPC classification number: A61K38/39 , A23L29/284 , A23L33/105 , A23L33/155 , A23L33/16 , A23L33/17 , A23L33/40 , A61K31/122 , A61K31/593 , A61K33/06 , A61K36/126 , A61K36/39 , A61K36/46 , A61P19/00 , A23J3/342 , A23V2002/00 , A23V2250/5422 , A61K2236/31 , A61K2236/333 , A61K2236/37 , A61K2236/51 , A61K2236/53
Abstract: A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.
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公开(公告)号：US20220152162A1
公开(公告)日：2022-05-19
申请号：US17156534
申请日：2021-01-23
Applicant: Chenland Nutritionals Inc. , Qingdao Chenland Pharmaceutical Technology Development Co., Ltd.
Inventor： Shengcan Zou , Zengliang Zhang , Jiancheng Zong , Wenyu Li , Xin Li , Li Li , Shanglong Wang , Lei Zong
IPC: A61K38/39 , A61K33/06 , A61K31/122 , A61K31/593 , A61K36/46 , A61K36/126 , A61K36/39 , A61P19/00 , A23L33/00 , A23L33/17 , A23L33/16 , A23L33/155 , A23L33/105
Abstract: A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20200237805A1
公开(公告)日：2020-07-30
申请号：US16846455
申请日：2020-04-13
Applicant: Chenland Nutritionals, Inc.
Inventor： Shengcan Zou , Li Li , Lei Zong , Jiancheng Zong , Shanglong Wang , Zengliang Zhang
IPC: A61K31/737 , A61K47/42 , A61K31/7008 , A61K36/296 , A61K36/537 , A61K36/8945 , A61K36/126 , A61K36/39 , A61K9/00 , A61P19/02
Abstract: The present invention discloses a compound composition with function of promoting bone and joint health and an application thereof. In the present invention, glucosamine is combined with collagen, chondroitin sulfate and traditional Chinese medicine extract to prepare the compound composition with function of promoting bone and joint health. The compound composition can shorten onset time. At the same time, the traditional Chinese medicine extract for treating the bone and joint problems is added, to reduce the market impact of adding only modern joint health ingredients. Moreover, the compound composition disclosed by the present invention can be used as a dietary supplement or health food raw material for preventing or treating moderate to mild osteoarthritis. Thus, the compound composition disclosed by the present invention is suitable for promotion and application.
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7.发明授权公开(公告)号：US11517602B2
公开(公告)日：2022-12-06
申请号：US17035808
申请日：2020-09-29
Applicant: Chenland Nutritionals Inc.
Inventor： Shengcan Zou , Zengliang Zhang , Jiancheng Zong , Wenyu Li , Xin Li , Li Li , Shanglong Wang , Lei Zong
Abstract: A traditional Chinese medicine composition includes 60%-80% by weight of Eucommia ulmoides extract, 15%-30% by weight of Rhizoma Drynariae extract and 5%-10% by weight of Semen Cuscutae extract. A method of preparing the traditional Chinese medicine composition is also provided. Uses of the traditional Chinese medicine composition in the prevention and/or treatment of osteoporosis are also provided.
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公开(公告)号：US20220226413A1
公开(公告)日：2022-07-21
申请号：US17693327
申请日：2022-03-12
Inventor： Shengcan Zou , Shanglong Wang , Xin Li , Lei Zong , Jiancheng Zong , Zengliang Zhang
IPC: A61K36/69 , A61K36/8988 , A61K36/882 , A61K36/64 , A61K47/69
Abstract: The present disclosure relates to the technical field of traditional Chinese medicine, and more specifically, to a traditional Chinese medicine composition with improving cognition effect, its preparation method and a traditional Chinese medicine preparation. In parts by weight, the traditional Chinese medicine composition is made from 1-20 parts of Gastrodiae Rhizoma, 1-15 parts of Polygala tenuifolia Willd., 1-30 parts of Acorus tatarinowii, 0.1-10 parts of Cistanche deserticola Ma, 0.1-10 parts of Rehmanniae Radix Praeparata, and 0.01-1 parts of curcumin. The pharmacodynamic substances of Gastrodiae Rhizoma, Polygala tenuifolia Willd., Acorus tatarinowii, Cistanche deserticola Ma and Rehmanniae Radix Praeparata are extracted completely, concentrated and dried as much as possible. The volatile oil of Acorus tatarinowii and curcumin are encapsulated and dried by the volatile oil encapsulation technology. The dry powder of the traditional Chinese medicine compound extract is evenly mixed with the volatile oil encapsulation compound.
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公开(公告)号：US20220326200A1
公开(公告)日：2022-10-13
申请号：US17743414
申请日：2022-05-12
Inventor： Shengcan ZOU , Shanglong Wang , Xin Li , Lei Zong , Jiancheng Zong , Zengliang Zhang
Abstract: A method for establishing fingerprint of traditional Chinese medicine compound or its preparation with improving cognition is disclosed. By weight, the traditional Chinese medicine compound is made from following raw materials: 1-20 parts of Gastrodiae Rhizoma, 1-15 parts of Polygala tenuifolia, 1-30 parts of Acorus tatarinowii, 0.1-10 parts of Cistanche deserticola Ma, 0.1-10 parts of Rehmanniae Radix Praeparata, and 0.01-1 parts of curcumin. A chromatogram of a test sample solution is established by high performance liquid chromatography. Chromatographic conditions are as follows: a chromatographic column is octadecyl silane bonded silica gel chromatographic column. A column temperature is 25˜35 ° C. A flow rate is 0.9˜ 1.1 ml/min. Detection wavelengths are 210˜230 nm and 310˜330 nm respectively. A mobile phase A is acetonitrile and a mobile phase B is water. And gradient elution is carried out.
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公开(公告)号：US20210109068A1
公开(公告)日：2021-04-15
申请号：US17094840
申请日：2020-11-11
Applicant: Chenland Nutritionals Inc. , Qingdao Chenland Pharmaceutical Technology Development Co., Ltd.
Inventor： Shengcan Zou , Jiancheng Zong , Wenyu Li , Lei Zong , Zengliang Zhang , Shanglong Wang
IPC: G01N30/86 , B01J20/286 , B01J20/10 , A61K36/185 , A61K36/65 , A61K36/744 , A61K36/48 , G01N30/06 , G01N30/60
Abstract: The present invention discloses a fingerprint detection method for an antidepressant drug, which adopts liquid chromatography to characterize pharmacological active ingredients of the antidepressant drug composed of Hypericum perforatum L., Paeonia lactiflora Pall, Gardenia jasminoides Ellis, Albizia julibrissin Durazz, and Moutan Cortex, provides an effective detection method, and realizes the quality control of traditional Chinese medicine compositions. The fingerprint detection method provided by the present invention has the advantages of high repeatability and high stability.
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