公开(公告)号：US11331380B2

公开(公告)日：2022-05-17

申请号：US16343375

申请日：2017-10-19

Applicant: CELGENE CORPORATION

Inventor： Shuichan Xu

IPC: A61K39/00 ,  A61P35/00 ,  A61K39/395 ,  A61K31/454 ,  A61K45/06 ,  A61K31/7088 ,  C07K14/47 ,  C07K14/705 ,  C07K16/28 ,  C07K16/30 ,  C07K16/32

Abstract: Provided herein are modified T lymphocytes comprising chimeric receptors and methods thereof.

公开(公告)号：US11325889B2

公开(公告)日：2022-05-10

申请号：US16719217

申请日：2019-12-18

Applicant: Celgene Corporation

Inventor： Massimo Ammirante ,  Sogole Bahmanyar ,  Matthew D. Correa ,  Virginia Grant ,  Joshua Hansen ,  Evan J. Horn ,  Timothy S. Kercher ,  Christopher Mayne ,  Mark A. Nagy ,  Rama Krishna Narla ,  Surendra Nayak ,  Stephen Norris ,  Patrick Papa ,  Veronique Plantevin-Krenitsky ,  John J. Sapienza ,  Brandon W. Whitefield ,  Shuichan Xu

IPC: C07D211/94 ,  C07D233/86 ,  C07D211/98 ,  C07D233/30

Abstract: Provided herein are piperidine dione compounds having the following structure: wherein RN, R1, R2, R3, R4, X, L, V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

公开(公告)号：US20240368083A1

公开(公告)日：2024-11-07

申请号：US18521663

申请日：2023-11-28

Applicant: Celgene Corporation

Inventor： Massimo Ammirante ,  Sogole Bahmanyar ,  Matthew D. Correa ,  Virginia Heather Sharron Grant ,  Joshua Hansen ,  Evan J. Horn ,  Timothy S. Kercher ,  Christopher Mayne ,  Mark A. Nagy ,  Rama Krishna Narla ,  Surendra Nayak ,  Stephen Norris ,  Patrick Papa ,  Veronique Plantevin-Krenitsky ,  John J. Sapienza ,  Brandon W. Whitefield ,  Shuichan Xu

IPC: C07D211/94 ,  C07D233/30

Abstract: Provided herein are piperidine dione compounds having the following structure: wherein RN, R1, R2, R3, R4, L, V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

公开(公告)号：US11873283B2

公开(公告)日：2024-01-16

申请号：US17403742

申请日：2021-08-16

Applicant: Celgene Corporation

Inventor： Massimo Ammirante ,  Sogole Bahmanyar ,  Matthew D. Correa ,  Virginia Heather Sharron Grant ,  Joshua Hansen ,  Evan J. Horn ,  Timothy S. Kercher ,  Christopher Mayne ,  Mark A. Nagy ,  Rama Krishna Narla ,  Surendra Nayak ,  Stephen Norris ,  Patrick Papa ,  Veronique Plantevin-Krenitsky ,  John J. Sapienza ,  Brandon W. Whitefield ,  Shuichan Xu

IPC: C07D211/94 ,  C07D233/30

CPC classification number: C07D211/94 ,  C07D233/30

Abstract: Provided herein are piperidine dione compounds having the following structure:






wherein RN, R1, R2, R3, R4, L, V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

公开(公告)号：US20230002321A1

公开(公告)日：2023-01-05

申请号：US17403742

申请日：2021-08-16

Applicant: Celgene Corporation

Inventor： Massimo Ammirante ,  Sogole Bahmanyar ,  Matthew D. Correa ,  Virginia Heather Sharron Grant ,  Joshua Hansen ,  Evan J. Horn ,  Timothy S. Kercher ,  Christopher Mayne ,  Mark A. Nagy ,  Rama Krishna Narla ,  Surendra Nayak ,  Stephen Norris ,  Patrick Papa ,  Veronique Plantevin-Krenitsky ,  John J. Sapienza ,  Brandon W. Whitefield ,  Shuichan Xu

IPC: C07D211/94 ,  C07D233/30

Abstract: Provided herein are piperidine dione compounds having the following structure: wherein RN, R1, R2, R3, R4, L, V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.

公开(公告)号：US20190240304A1

公开(公告)日：2019-08-08

申请号：US16343375

申请日：2017-10-19

Applicant: CELGENE CORPORATION

Inventor： Shuichan Xu

IPC: A61K39/00 ,  A61P35/00 ,  C07K16/32 ,  C07K16/30 ,  C07K16/28 ,  C07K14/47 ,  C07K14/705

CPC classification number: A61K39/0011 ,  A61K31/454 ,  A61K31/7088 ,  A61K39/395 ,  A61K45/06 ,  A61K2039/5156 ,  A61P35/00 ,  C07K14/4702 ,  C07K14/70521 ,  C07K16/2878 ,  C07K16/3069 ,  C07K16/32 ,  C07K2319/03 ,  A61K2300/00

Abstract: Provided herein are modified T lymphocytes comprising chimeric receptors and methods thereof.

公开(公告)号：US11149007B2

公开(公告)日：2021-10-19

申请号：US16719171

申请日：2019-12-18

Applicant: Celgene Corporation

Inventor： Massimo Ammirante ,  Sogole Bahmanyar ,  Matthew D. Correa ,  Virginia Heather Sharron Grant ,  Joshua Hansen ,  Evan J. Horn ,  Timothy S. Kercher ,  Christopher Mayne ,  Mark A. Nagy ,  Rama Krishna Narla ,  Surendra Nayak ,  Stephen Norris ,  Patrick Papa ,  Veronique Plantevin-Krenitsky ,  John J. Sapienza ,  Brandon W. Whitefield ,  Shuichan Xu

IPC: C07D211/94 ,  C07D233/30

Abstract: Provided herein are piperidine dione compounds having the following structure: wherein RN, R1, R2, R3, R4, L, V, m, and n are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.