公开(公告)号：US11756183B2

公开(公告)日：2023-09-12

申请号：US16625562

申请日：2018-06-23

申请人： CORNELL UNIVERSITY

发明人： Samie R. Jaffrey ,  Jacob L. Litke

IPC分类号： A61K31/7115 ,  G06T7/00 ,  G06T7/11 ,  C12N15/115 ,  C12N15/63 ,  G01N21/88 ,  G01N21/95 ,  G01N21/956

CPC分类号： G06T7/001 ,  A61K31/7115 ,  C12N15/115 ,  C12N15/63 ,  G01N21/8851 ,  G01N21/9501 ,  G01N21/95607 ,  G06T7/11 ,  C12N2310/128 ,  C12N2310/16 ,  C12N2310/3519 ,  C12N2310/51 ,  C12N2310/532 ,  G01N2021/95615 ,  G06T2207/20104 ,  G06T2207/30148

摘要： The present invention relates to a RNA molecule comprising a first ribozyme, a first ligation sequence, an effector molecule, a second ligation sequence, and a second ribozyme. Methods of producing circular RNA molecules and treatment methods are also disclosed.