公开(公告)号：US20150284731A1

公开(公告)日：2015-10-08

申请号：US14434595

申请日：2012-12-05

Applicant: BIOCON LIMITED

Inventor： Nagaraj Govindappa ,  Sankar Periyasamy ,  Shivakumar Madenahalli Channabasappa ,  Suma Sreenivas ,  Kedamath Nanjund Sastry

IPC: C12N15/81 ,  C07K14/81 ,  C07K14/76 ,  C12P19/34 ,  C12P21/00

CPC classification number: C12N15/815 ,  C07K14/76 ,  C07K14/811 ,  C12N9/0006 ,  C12P19/34 ,  C12P21/00 ,  C12P21/02 ,  C12Y101/01014

Abstract: The present disclosure relates to a process of identification and isolation of sorbitol dehydrogenase promoter from Pichia pastoris. Further, the present disclosure also relates to expression of heterologous proteins under the control of Sorbitol dehydrogenase promoter in Pichia pastoris.

Abstract translation: 本公开涉及从巴斯德毕赤酵母中鉴定和分离山梨醇脱氢酶启动子的方法。 此外，本公开还涉及在巴斯德毕赤酵母中在山梨糖醇脱氢酶启动子控制下的异源蛋白质的表达。

公开(公告)号：US09862958B2

公开(公告)日：2018-01-09

申请号：US14434595

申请日：2012-12-05

Applicant: Biocon Limited

Inventor： Nagaraj Govindappa ,  Sankar Periyasamy ,  Shivakumar Madenahalli Channabasappa ,  Suma Sreenivas ,  Kedamath Nanjund Sastry

IPC: C12P21/00 ,  C12N15/81 ,  C12P19/34 ,  C07K14/76 ,  C07K14/81 ,  C12N9/04 ,  C12P21/02

CPC classification number: C12N15/815 ,  C07K14/76 ,  C07K14/811 ,  C12N9/0006 ,  C12P19/34 ,  C12P21/00 ,  C12P21/02 ,  C12Y101/01014

Abstract: The present disclosure relates to a process of identification and isolation of sorbitol dehydrogenase promoter from Pichia pastoris. Further, the present disclosure also relates to expression of heterologous proteins under the control of Sorbitol dehydrogenase promoter in Pichia pastoris.

公开(公告)号：US20160168198A1

公开(公告)日：2016-06-16

申请号：US14904035

申请日：2014-06-27

Applicant: Biocon Limited

Inventor： Nagaraj Govindappa ,  Suma Sreenivas ,  Sankar Periyasamy ,  Srividya Divakar

IPC: C07K7/08 ,  C07K14/415 ,  C12N15/81

CPC classification number: C07K7/08 ,  C07K14/39 ,  C07K14/415 ,  C07K2319/02 ,  C07K2319/50 ,  C12N15/815

Abstract: The present invention relates to a signal sequence from a unique Pichia pastoris protein. Further the invention discloses use of signal sequence for the expression of heterologous protein in Pichia pastoris.

Abstract translation: 本发明涉及来自独特巴斯德毕赤酵母蛋白的信号序列。 此外，本发明公开了信号序列用于在巴斯德毕赤酵母中表达异源蛋白质的用途。