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公开(公告)号:US11759776B2
公开(公告)日:2023-09-19
申请号:US17961685
申请日:2022-10-07
Applicant: BECTON, DICKINSON AND COMPANY
Inventor: Timothy Roy Hansen , Tong Zhou
CPC classification number: B01L3/0241 , C12M1/26 , C12M33/04 , G01N35/1016 , G01V8/16
Abstract: Systems and methods for positive dispense verification. In one aspect, a system has a plurality of light emitters. The light from the emitters is directed toward a plurality of light detectors across a proximately horizontal plane. The liquid dispense device is positioned above the horizontal plane of light emission from the plurality of light emitters to the plurality of light detectors such that the dispensed liquid will travel through the horizontal plane defined by the emitted light and onto the container being inoculated. Each of the plurality of detectors is coupled to an amplifier. The amplifier generates a signal in response to an interrupt in the transmission of light from the light emitters to the light detectors when the light path is disrupted by the dispense of liquid confirming the liquid was dispensed onto the container.
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公开(公告)号:US20180243735A1
公开(公告)日:2018-08-30
申请号:US15903767
申请日:2018-02-23
Applicant: BECTON DICKINSON AND COMPANY
Inventor: John D. Mantlo , Tong Zhou
CPC classification number: B01L3/021 , B01L3/0275 , B01L2300/0627 , B01L2300/069 , B01L2400/0487 , C12Q1/24 , G01N1/12 , G01N35/00584 , G01N35/0099 , G01N35/10 , G01N2001/028 , G01N2035/1027 , G01N2035/103
Abstract: The present disclosure describes pipette tips haying an absorbent material (e.g., a flocking material) anchored to a distal end of the pipette tip and related methods of use. In some embodiments, the flocked pipette tips can be used in an automated process and/or system, wherein the contact between the pipette tips and either a sample or a culture medium can be automatically sensed for accurate sample collection and/or dispense. In some embodiments, automatic detection of the liquid interface may be accomplished by detecting a threshold change in capacitance when the pipette tip contacts the sample liquid interface (e.g., for sample collection) or the agar interface (e.g., for sample release). In some embodiments, the automated process and/or system may utilize one or more predetermined, fixed heights for collecting samples and/or depositing samples.
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公开(公告)号:US09931644B2
公开(公告)日:2018-04-03
申请号:US15192440
申请日:2016-06-24
Applicant: Becton, Dickinson and Company
Inventor: Kevin Bailey , Christopher Embres , Donald Gorelick , Timothy R. Hansen , Dwight Livingston , Andre Scherz , Gerard Sevigny , Mark Talmer , Tong Zhou , Spencer Lovette
CPC classification number: B04B5/0414 , B01D43/00 , B04B11/043 , G01N35/026 , G01N35/04 , G01N2035/00495 , G01N2035/0405 , G01N2035/0425 , G01N2035/0465
Abstract: A system for automatically processing a biological specimen is provided that includes an elevator comprising a plurality of shelves configured to receive a plurality of sample trays. The trays may comprise a plurality of sample containers containing a sample and having a plurality of respective caps engaged therewith. The trays may further include a plurality of centrifuge tube racks each containing a plurality of centrifuge tubes. The system may include a first transport mechanism, a second transport mechanism and a third transport mechanism. The system may include a chain-of-custody device configured to read identifiers on each of the containers. The system may also include a pipetting device configured to remove a portion from the sample containers and dispense the sample into the centrifuge tubes.
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公开(公告)号:US20230032776A1
公开(公告)日:2023-02-02
申请号:US17961685
申请日:2022-10-07
Applicant: BECTON, DICKINSON AND COMPANY
Inventor: Timothy Roy Hansen , Tong Zhou
Abstract: Systems and methods for positive dispense verification. In one aspect, a system has a plurality of light emitters. The light from the emitters is directed toward a plurality of light detectors across a proximately horizontal plane. The liquid dispense device is positioned above the horizontal plane of light emission from the plurality of light emitters to the plurality of light detectors such that the dispensed liquid will travel through the horizontal plane defined by the emitted light and onto the container being inoculated. Each of the plurality of detectors is coupled to an amplifier. The amplifier generates a signal in response to an interrupt in the transmission of light from the light emitters to the light detectors when the light path is disrupted by the dispense of liquid confirming the liquid was dispensed onto the container.
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公开(公告)号:US09381524B2
公开(公告)日:2016-07-05
申请号:US13672302
申请日:2012-11-08
Applicant: Becton, Dickinson and Company
Inventor: Kevin Bailey , Christopher Embres , Donald Gorelick , Timothy R. Hansen , Dwight Livingston , Andre Scherz , Gerard Sevigny , Mark Talmer , Tong Zhou , Spencer Lovette
CPC classification number: B04B5/0414 , B01D43/00 , B04B11/043 , G01N35/026 , G01N35/04 , G01N2035/00495 , G01N2035/0405 , G01N2035/0425 , G01N2035/0465
Abstract: A system for automatically processing a biological specimen is provided that includes an elevator comprising a plurality of shelves configured to receive a plurality of sample trays. The trays may comprise a plurality of sample containers containing a sample and having a plurality of respective caps engaged therewith. The trays may further include a plurality of centrifuge tube racks each containing a plurality of centrifuge tubes. The system may include a first transport mechanism, a second transport mechanism and a third transport mechanism. The system may include a chain-of-custody device configured to read identifiers on each of the containers. The system may also include a pipetting device configured to remove a portion from the sample containers and dispense the sample into the centrifuge tubes.
Abstract translation: 提供了一种用于自动处理生物样本的系统,其包括电梯,其包括被配置为接收多个样品盘的多个搁架。 托盘可以包括多个容纳样品并且具有与其接合的多个相应盖的样品容器。 托盘还可以包括多个离心管架,每个离心管架包含多个离心管。 该系统可以包括第一输送机构,第二输送机构和第三输送机构。 该系统可以包括被配置为读取每个容器上的标识符的链监控设备。 该系统还可以包括移液装置,该移液装置构造成从样品容器中移除部分并将样品分配到离心管中。
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公开(公告)号:US11291986B2
公开(公告)日:2022-04-05
申请号:US15903767
申请日:2018-02-23
Applicant: BECTON DICKINSON AND COMPANY
Inventor: John D. Mantlo , Tong Zhou
Abstract: The present disclosure describes pipette tips having an absorbent material (e.g., a flocking material) anchored to a distal end of the pipette tip and related methods of use. In some embodiments, the flocked pipette tips can be used in an automated process and/or system, wherein the contact between the pipette tips and either a sample or a culture medium can be automatically sensed for accurate sample collection and/or dispense. In some embodiments, automatic detection of the liquid interface may be accomplished by detecting a threshold change in capacitance when the pipette tip contacts the sample liquid interface (e.g., for sample collection) or the agar interface (e.g., for sample release). In some embodiments, the automated process and/or system may utilize one or more predetermined, fixed heights for collecting samples and/or depositing samples.
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公开(公告)号:US20160318040A1
公开(公告)日:2016-11-03
申请号:US15192440
申请日:2016-06-24
Applicant: Becton, Dickinson and Company
Inventor: Kevin Bailey , Christopher Embres , Donald Gorelick , Timothy R. Hansen , Dwight Livingston , Andre Scherz , Gerard Sevigny , Mark Talmer , Tong Zhou , Spencer Lovette
CPC classification number: B04B5/0414 , B01D43/00 , B04B11/043 , G01N35/026 , G01N35/04 , G01N2035/00495 , G01N2035/0405 , G01N2035/0425 , G01N2035/0465
Abstract: A system for automatically processing a biological specimen is provided that includes an elevator comprising a plurality of shelves configured to receive a plurality of sample trays. The trays may comprise a plurality of sample containers containing a sample and having a plurality of respective caps engaged therewith. The trays may further include a plurality of centrifuge tube racks each containing a plurality of centrifuge tubes. The system may include a first transport mechanism, a second transport mechanism and a third transport mechanism. The system may include a chain-of-custody device configured to read identifiers on each of the containers. The system may also include a pipetting device configured to remove a portion from the sample containers and dispense the sample into the centrifuge tubes.
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