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    Biological fluid separation device
    1.
    发明授权
    Biological fluid separation device 有权

    公开(公告)号：US11305241B2

    公开(公告)日：2022-04-19

    申请号：US16658350

    申请日：2019-10-21

    Applicant: BECTON DICKINSON AND COMPANY

    Inventor： Qihua Xu ,  Kristin Weidemaier ,  Christopher Basciano ,  Sivaramakrishnan Balasubramanian ,  Patrick Downie

    IPC: B01D63/08 ,  G01N33/49 ,  B01D71/50 ,  B01D63/02 ,  A61M1/34 ,  B01D29/00 ,  A61M1/16 ,  B01D69/06

    Abstract: A biological fluid separation device adapted to receive a biological fluid sample having a first portion and a second portion is disclosed. The device includes a housing having a first chamber having a first chamber inlet for receiving the biological fluid sample therein and a first chamber outlet. The housing has a second chamber having a second chamber inlet and a second chamber outlet, and a separation member separating at least a portion of the first chamber outlet and the second chamber. The separation member is adapted to restrain the first portion of the biological fluid sample within the first chamber and to allow at least a portion of the second portion of the biological fluid sample to pass into the second chamber. An actuator, such as a vacuum source, draws the biological fluid sample into the first chamber and the second portion into the second chamber.

    METHOD OF PIERCING SEAL FOR SAMPLE TESTING
    4.
    发明公开
    METHOD OF PIERCING SEAL FOR SAMPLE TESTING 审中-公开

    公开(公告)号：US20240210435A1

    公开(公告)日：2024-06-27

    申请号：US18587777

    申请日：2024-02-26

    Applicant: BECTON, DICKINSON AND COMPANY

    Inventor： Patrick Walter Truitt ,  Patrick Downie ,  Ammon D. Lentz ,  Alyssa Nicolaisen Shedlosky

    IPC: G01N35/10 ,  B01L3/00

    CPC classification number: G01N35/1079 ,  B01L3/5029 ,  B01L2300/0672

    Abstract: Disclosed herein include methods, compositions, and kits suitable for use in sample testing. The sample testing systems can comprise a cartridge body to receive a sample, at least one reaction chamber coupled to the cartridge body, and at least one seal between the cartridge body and the at least one reaction chamber. The sample testing system can comprise a sample dispensing mechanism operable to disrupt the at least one seal to dispense a predetermined sub-volume of sample fluid from the cartridge body into the at least one reaction chamber. The sample dispensing mechanism can comprise a dispense rod comprising at least one piercing tip that disrupts the at least one seal by forming at least one opening therein. The piercing tips can comprise a geometry configured to generate a large opening in the at least one seal.

    Biological fluid separation device
    6.
    发明授权
    Biological fluid separation device 有权

    公开(公告)号：US11344851B2

    公开(公告)日：2022-05-31

    申请号：US16658350

    申请日：2019-10-21

    Applicant: BECTON DICKINSON AND COMPANY

    Inventor： Qihua Xu ,  Kristin Weidemaier ,  Christopher Basciano ,  Sivaramakrishnan Balasubramanian ,  Patrick Downie

    IPC: B01D63/08 ,  G01N33/49 ,  B01D71/50 ,  B01D63/02 ,  A61M1/16 ,  A61M1/34 ,  B01D29/00 ,  B01D69/06

    Abstract: A biological fluid separation device adapted to receive a biological fluid sample having a first portion and a second portion is disclosed. The device includes a housing having a first chamber having a first chamber inlet for receiving the biological fluid sample therein and a first chamber outlet. The housing has a second chamber having a second chamber inlet and a second chamber outlet, and a separation member separating at least a portion of the first chamber outlet and the second chamber. The separation member is adapted to restrain the first portion of the biological fluid sample within the first chamber and to allow at least a portion of the second portion of the biological fluid sample to pass into the second chamber. An actuator, such as a vacuum source, draws the biological fluid sample into the first chamber and the second portion into the second chamber.

    Use of Automatic Flow Regulators for Flow Modulation During Blood Collection
    9.
    发明申请
    Use of Automatic Flow Regulators for Flow Modulation During Blood Collection 审中-公开
    采集自动流量调节器进行流量调节

    公开(公告)号：US20170027491A1

    公开(公告)日：2017-02-02

    申请号：US15291541

    申请日：2016-10-12

    Applicant: Becton, Dickinson and Company

    Inventor： Patrick Downie ,  Jamieson W. Crawford ,  Craig Owen Russ

    IPC: A61B5/15 ,  A61B5/154 ,  A61B5/153

    CPC classification number: A61B5/150946 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150732 ,  A61B5/153 ,  A61B5/154 ,  A61M39/24 ,  A61M2039/0666 ,  A61M2039/2433 ,  A61M2039/244 ,  A61M2039/246 ,  Y10T137/7847

    Abstract: A flow regulator for a blood collection assembly includes a housing having an inlet and an outlet, which defines an interior space between the inlet and the outlet. A membrane having a first surface and a second surface is disposed at least partially within the interior space. The membrane has a first position where a flow path between the inlet and the outlet is substantially open, and a second position where the flow path between the inlet and the outlet is at least partially restricted. The membrane is configured to move between the first and second positions in response to a pressure differential acting on the membrane.

    Abstract translation: 用于采血组件的流量调节器包括具有入口和出口的壳体，其限定入口和出口之间的内部空间。 具有第一表面和第二表面的膜至少部分地设置在内部空间内。 膜具有第一位置，其中入口和出口之间的流动路径基本上是开放的，而第二位置，入口和出口之间的流动路径至少部分地被限制。 膜被配置为响应于作用在膜上的压差而在第一和第二位置之间移动。

    Use of Automatic Flow Regulators for Flow Modulation During Blood Collection
    10.
    发明申请
    Use of Automatic Flow Regulators for Flow Modulation During Blood Collection 审中-公开
    采集自动流量调节器进行流量调节

    公开(公告)号：US20130178760A1

    公开(公告)日：2013-07-11

    申请号：US13737160

    申请日：2013-01-09

    Applicant: Becton, Dickinson and Company

    Inventor： Patrick Downie ,  Jamieson W. Crawford ,  Craig Owen Russ

    IPC: A61B5/15

    CPC classification number: A61B5/150946 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150732 ,  A61B5/153 ,  A61B5/154 ,  A61M39/24 ,  A61M2039/0666 ,  A61M2039/2433 ,  A61M2039/244 ,  A61M2039/246 ,  Y10T137/7847

    Abstract: A flow regulator for a blood collection assembly includes a housing having an inlet and an outlet, which defines an interior space between the inlet and the outlet. A membrane having a first surface and a second surface is disposed at least partially within the interior space. The membrane has a first position where a flow path between the inlet and the outlet is substantially open, and a second position where the flow path between the inlet and the outlet is at least partially restricted. The membrane is configured to move between the first and second positions in response to a pressure differential acting on the membrane.

    Abstract translation: 用于采血组件的流量调节器包括具有入口和出口的壳体，其限定入口和出口之间的内部空间。 具有第一表面和第二表面的膜至少部分地设置在内部空间内。 膜具有第一位置，其中入口和出口之间的流动路径基本上是开放的，而第二位置，入口和出口之间的流动路径至少部分地被限制。 膜被配置为响应于作用在膜上的压差而在第一和第二位置之间移动。

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