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公开(公告)号：US20250076163A1
公开(公告)日：2025-03-06
申请号：US18954635
申请日：2024-11-21
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Timothy Wiles , John D. Mantlo
IPC: G01N1/38 , G01N1/28 , G01N1/40 , G01N1/44 , G01N15/075 , G01N35/00 , G01N35/10 , H01J49/04 , H01J49/40
Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
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公开(公告)号：US20220364965A1
公开(公告)日：2022-11-17
申请号：US17747563
申请日：2022-05-18
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Timothy Wiles , John D. Mantlo
Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
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公开(公告)号：US20200080919A1
公开(公告)日：2020-03-12
申请号：US16570006
申请日：2019-09-13
Applicant: BECTON DICKINSON AND COMPANY
Inventor： Timothy Wiles , John D. Mantlo
Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
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公开(公告)号：US20180334701A1
公开(公告)日：2018-11-22
申请号：US15905422
申请日：2018-02-26
Applicant: Becton, Dickinson and Company
Inventor： Mei Yang-Woytowitz , Charles Yu , Timothy Wiles
Abstract: Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.
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公开(公告)号：US09085794B2
公开(公告)日：2015-07-21
申请号：US13778767
申请日：2013-02-27
Applicant: Becton, Dickinson and Company
Inventor： Mei Yang-Woytowitz , Charles Yu , Timothy Wiles
CPC classification number: C12Q1/34 , C12Q1/04 , G01N2333/986
Abstract: Presented herein are kits for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The kits presented herein include kits that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.
Abstract translation: 本文提供了用于检测特异性β-内酰胺酶的试剂盒，包括A类丝氨酸碳青霉烯酶，金属β-内酰胺酶，AmpCβ-内酰胺酶和扩展谱β-内酰胺酶（ESBL）。 本文提供的试剂盒包括允许在短短2至10分钟内检测细菌样品中特定β-内酰胺酶的存在的试剂盒。
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Patent Agency Ranking
公开(公告)号：US12181392B2
公开(公告)日：2024-12-31
申请号：US18236144
申请日：2023-08-21
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Timothy Wiles , John D. Mantlo
IPC: G01N1/38 , G01N1/28 , G01N1/40 , G01N1/44 , G01N35/00 , G01N35/10 , G01N15/075 , H01J49/04 , H01J49/40
Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
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公开(公告)号：US20240018567A1
公开(公告)日：2024-01-18
申请号：US18165051
申请日：2023-02-06
Applicant: Becton, Dickinson and Company
Inventor： Mei Yang-Woytowitz , Charles Yu , Timothy Wiles
CPC classification number: C12Q1/34 , C12Q1/04 , G01N2333/986
Abstract: Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.
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公开(公告)号：US11774332B2
公开(公告)日：2023-10-03
申请号：US17747563
申请日：2022-05-18
Applicant: BECTON, DICKINSON AND COMPANY
Inventor： Timothy Wiles , John D. Mantlo
IPC: G01N1/38 , G01N1/28 , G01N1/40 , G01N1/44 , G01N35/00 , G01N35/10 , H01J49/04 , G01N15/06 , H01J49/40
CPC classification number: G01N1/38 , G01N1/2813 , G01N1/4022 , G01N1/44 , G01N35/00722 , G01N35/1016 , G01N2001/4027 , G01N2015/0693 , H01J49/0413 , H01J49/0418 , H01J49/0468 , H01J49/40
Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
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公开(公告)号：US11572579B2
公开(公告)日：2023-02-07
申请号：US16920276
申请日：2020-07-02
Applicant: Becton, Dickinson and Company
Inventor： Mei Yang-Woytowitz , Charles Yu , Timothy Wiles
Abstract: Presented herein are methods, compositions, and kits for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes.
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公开(公告)号：US20170234780A1
公开(公告)日：2017-08-17
申请号：US15504549
申请日：2015-08-17
Applicant: Becton, Dickinson and Company
Inventor： Timothy Wiles , John D. Mantlo
CPC classification number: G01N1/38 , G01N1/2813 , G01N1/4022 , G01N1/44 , G01N35/00722 , G01N35/1016 , G01N2001/4027 , G01N2015/0693 , H01J49/0413 , H01J49/0418 , H01J49/0468 , H01J49/40
Abstract: Methods for preparing a biological sample for testing by Maldi where such methods are selected based on sample parameters. Maldi scores are obtained for a range of sample parameters (e.g. McFarland, dispense volume and number of dispenses). From the data, sample preparation parameters can be selected for a biological sample being prepared for Maldi testing. One sample preparation strategy uses multiple dispenses of sample with an intervening drying step, which yields more accurate Maldi scores, particularly for samples at the low range of McFarland values (e.g. below about 2).
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