公开(公告)号：US3787124A

公开(公告)日：1974-01-22

申请号：US3787124D

申请日：1972-09-21

Applicant: BAXTER LABORATORIES INC

Inventor： LOWY G ,  PRIARONE P ,  CULLIS H

IPC: G01N21/00 ,  G01N21/27 ,  G01N21/31 ,  G01N31/16 ,  G01N33/72 ,  G01N21/24

CPC classification number: G01N21/314

Abstract: A dual wavelength photometer for measuring the oxygenation characteristics of blood. Light is passed through two different filters on a rotating time-sharing wheel, one filter providing a reference wave length at which there is substantially no absorbance change as between oxygenated and deoxygenated blood, the other filter providing a wavelength at which there is maximum absorbance change. The two wavelengths are sequentially passed through a cuvette containing deoxygenated blood being treated at controlled rates with an oxygenating reagent and changes in absorbance are detected by a photomultiplier which generates corresponding signals. A time-shared difference-measuring circuit, synchronized with the rotating wheel, receives the signals and derives a resultant absorbance difference signal which is delivered to a recorder. The trace provided by the recorder shows the change in absorbance-difference with time as blood oxygenation proceeds.

Abstract translation: 用于测量血液氧合特性的双波长光度计。 光在旋转的分时轮上通过两个不同的过滤器，一个过滤器提供参考波长，在氧气和脱氧血液之间基本上没有吸光度变化，另一个过滤器提供最大吸光度变化的波长 。 两个波长依次通过含有用受氧剂处理的脱氧血液的比色皿，并通过产生相应信号的光电倍增管检测吸光度的变化。 与旋转轮同步的时间共享差分测量电路接收信号并导出被传送到记录器的合成吸收差信号。 由记录仪提供的踪迹显示随着血氧的进行，吸光度差异随时间的变化。

公开(公告)号：US3811781A

公开(公告)日：1974-05-21

申请号：US32649573

申请日：1973-01-26

Applicant: BAXTER LABORATORIES INC

Inventor： LOWY G

IPC: G01J3/42 ,  G01N21/31 ,  G01J3/48

CPC classification number: G01N21/314

Abstract: A multi-wavelength photometer using a two-segment rotating circular variable filter to select the working wavelengths. Selection is made by gating respective integrating circuits receiving signals generated by a light beam passing through the filter and the sample cuvette. The gating signals are produced by variable delay circuits triggered respectively by timing pulses derived from an apertured timing disc mounted on the same shaft as the rotating filter. The timing pulses are generated by spaced photo diodes located adjacent the timing disc and receiving light through the aperture of the timing disc as it passes.

Abstract translation: 一种使用双段旋转圆形可变滤波器选择工作波长的多波长光度计。 通过选通接收通过过滤器和样品比色皿的光束产生的信号的各个积分电路进行选择。 门控信号由分别由安装在与旋转滤波器相同的轴上的有孔定时盘导出的定时脉冲触发的可变延迟电路产生。 定时脉冲由位于定时盘附近的间隔光电二极管产生，并在通过定时盘的孔径时接收光。

公开(公告)号：US3787121A

公开(公告)日：1974-01-22

申请号：US3787121D

申请日：1972-12-18

Applicant: BAXTER LABORATORIES INC

Inventor： MARCUS B ,  LOWY G ,  CONLON J

IPC: G01J3/02 ,  G01J3/06 ,  G01J3/08 ,  G01J3/12 ,  G01J3/42 ,  G01J3/427

CPC classification number: G01J3/02 ,  G01J3/0232 ,  G01J3/0237 ,  G01J3/06 ,  G01J3/08 ,  G01J3/12 ,  G01J3/42 ,  G01J3/427

Abstract: A spectrophotometer of the two-beam type employing two adjustable monochromators and employing a rotating chopper disc to provide time-sharing operation, such as split-beam operation, dual wavelength operation, or other desired modes of operation. The chopper disc motor is stabilized by a fiber optic feedback system and cooperating electronic system utilizing light beams reflected by the underside of the chopper disc and photo diodes responding to these reflections. The main optical system includes an adjustable lens element coupled to one of the monochromators to compensate for variations in refractive index of the lens element with wavelength. The electronic readout system is gated by the chopper disc stabilizing system to maintain synchronism of the readout signals with the two monochromatic excitation beams.

Abstract translation: 采用两个可调单色器的双光束型分光光度计，并采用旋转斩光盘来提供分光操作，例如分光束操作，双波长操作或其它所需操作模式。 斩波盘电机由光纤反馈系统和协同电子系统稳定，利用由斩波盘的下侧反射的光束和响应于这些反射的光电二极管。 主光学系统包括耦合到单色仪中的一个的可调透镜元件，以补偿具有波长的透镜元件的折射率变化。 电子读出系统由斩波盘稳定系统门控，以保持读出信号与两个单色激发光束的同步。