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公开(公告)号：US20150259713A1
公开(公告)日：2015-09-17
申请号：US14423448
申请日：2013-09-03
Applicant: BASF SE
Inventor： Andrea Piatesi , Kai-Uwe Baldenius , Klaus Ditrich , Alois Kindler , Marta Zajaczkowski-Fischer , Ralf Boehling , Alwin Rehfinger
IPC: C12P7/64 , C07C51/235 , C07C51/373
CPC classification number: C12P7/6427 , C07C51/235 , C07C51/373 , C12P7/6409 , C12Y402/01053 , C07C59/147 , C07C55/20
Abstract: A process for preparing sebacic acid by reacting in a first step (i) linoleic acid with water catalyzed by an oleate hydratase to form 10-hydroxy-12-octadecenoic acid, in a second step (ii) pyrolysing the 10-hydroxy-12-octadecenoic acid to 1-octene and 10-oxo-decanoic acid and in a third step (iii) oxidizing the 10-oxo-decanoic acid to sebacic acid.
Abstract translation: 在第二步（ii）中热解10-羟基-12-十八碳烯酸，通过在第一步骤（i）中将亚油酸与由油酸水合酶催化形成10-羟基-12-十八碳烯酸的水反应制备癸二酸的方法， 十八碳烯酸至1-辛烯和10-氧代癸酸，并且在第三步骤（iii）中将10-氧代癸酸氧化成癸二酸。
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公开(公告)号：US09834798B2
公开(公告)日：2017-12-05
申请号：US14423448
申请日：2013-09-03
Applicant: BASF SE
Inventor： Andrea Piatesi , Kai-Uwe Baldenius , Klaus Ditrich , Alois Kindler , Marta Zajaczkowski-Fischer , Ralf Boehling , Alwin Rehfinger
IPC: C12P7/64 , C12N9/88 , C07H21/04 , C07K1/00 , C07C51/235 , C07C51/373
CPC classification number: C12P7/6427 , C07C51/235 , C07C51/373 , C12P7/6409 , C12Y402/01053 , C07C59/147 , C07C55/20
Abstract: A process for preparing sebacic acid by reacting in a first step (i) linoleic acid with water catalyzed by an oleate hydratase to form 10-hydroxy-12-octadecenoic acid, in a second step (ii) pyrolysing the 10-hydroxy-12-octadecenoic acid to 1-octene and 10-oxo-decanoic acid and in a third step (iii) oxidizing the 10-oxo-decanoic acid to sebacic acid.
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3.发明授权Method for biocatalytic production of nitriles from oximes and oxime dehydratases usable therein 有权从其中可用的肟和肟脱水酶生物催化生产腈的方法公开(公告)号：US09080191B2
公开(公告)日：2015-07-14
申请号：US13798365
申请日：2013-03-13
Applicant: BASF SE
Inventor： Andrea Piatesi , Wolfgang Siegel , Kai-Uwe Baldenius
CPC classification number: C12P13/002 , C12N9/88 , C12Y499/01007
Abstract: The present invention relates to novel methods for biocatalytic production of nitriles from oximes using oxime dehydratases and novel mutants with oxime dehydratase activity and use thereof in a process for biocatalytic production of nitriles, such as in particular for the production of citral nitrile, neral nitrile, geranial nitrile or citronellyl nitrile from citral oxime, neral oxime, geranial oxime or citronellal oxime; and oxime dehydratases usable therefor, nucleotide sequences therefor and expression constructs or microorganisms comprising these.
Abstract translation: 本发明涉及使用肟脱水酶的肟生物催化生产腈的新方法和具有肟脱水酶活性的新型突变体及其在生物催化生产腈的方法中的用途，特别是用于制备柠檬醛腈，腈类， 柠檬醛肟，香橼肟，香叶肟或香茅醛肟的香叶腈或香茅腈; 和可用于其的肟脱水酶，其核苷酸序列和包含它们的表达构建体或微生物。
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4.发明申请METHOD FOR BIOCATALYTIC PRODUCTION OF NITRILES FROM OXIMES AND OXIME DEHYDRATASES USABLE THEREIN 有权用于生物活性生产硝酸盐的方法及其可用的氧化脱氢酶公开(公告)号：US20130244298A1
公开(公告)日：2013-09-19
申请号：US13798365
申请日：2013-03-13
Applicant: BASF SE
Inventor： Andrea Piatesi , Wolfgang Siegel , Kai-Uwe Baldenius
CPC classification number: C12P13/002 , C12N9/88 , C12Y499/01007
Abstract: The present invention relates to novel methods for biocatalytic production of nitriles from oximes using oxime dehydratases and novel mutants with oxime dehydratase activity and use thereof in a process for biocatalytic production of nitriles, such as in particular for the production of citral nitrile, neral nitrile, geranial nitrile or citronellyl nitrile from citral oxime, neral oxime, geranial oxime or citronellal oxime; and oxime dehydratases usable therefor, nucleotide sequences therefor and expression constructs or microorganisms comprising these.
Abstract translation: 本发明涉及使用肟脱水酶的肟生物催化生产腈的新方法和具有肟脱水酶活性的新型突变体及其在生物催化生产腈的方法中的用途，特别是用于制备柠檬醛腈，腈类， 柠檬醛肟，香橼肟，香叶肟或香茅醛肟的香叶腈或香茅腈; 和可用于其的肟脱水酶，其核苷酸序列和包含它们的表达构建体或微生物。
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