公开(公告)号：US20170258743A1

公开(公告)日：2017-09-14

申请号：US15107100

申请日：2015-12-04

Applicant: Aurea Biolabs Private Limited

Inventor： Sreeraj Gopi ,  Joby Jacob ,  Robin George

IPC: A61K31/121 ,  A23L33/105

CPC classification number: A61K31/121 ,  A23L33/105 ,  A23V2002/00 ,  A61K47/6951 ,  C07C37/00 ,  C07C41/20 ,  C07C41/26 ,  C07C45/62 ,  C08B37/0015 ,  C07C43/23 ,  C07C49/225 ,  C07C49/255 ,  C07C49/245 ,  C07C39/12

Abstract: The present invention discloses a process for preparation of white curcumin from purified curcuminoids. The curcuminoids are obtained by solvent extraction and crystallization of dried turmeric powder. The autoclave is charged with ethyl acetate and the 95% purity curcuminoids mixture is added to and stirred for uniformity at room temperature. 5% (w/w) of 10% palladium carbon is added to the reaction mixture and allowed for hydrogenation in the presence of hydrogen gas at 2 lbps pressure and stirred continuously for 15 hours. Once the reaction is completed, the reaction mixture is filtered and washed with ethyl acetate. The ethyl acetate is distilled off and crude mass is stirred with water to obtain a solid precipitate. Finally, the solid obtained is filtered and dried to pale brown crystals of white curcumin. White curcumin is encapsulated with beta-cyclodextrin, which exhibited increased bioavailability. White curcumin also exhibited anti-oxidant and chemopreventive activities.

公开(公告)号：US11123396B2

公开(公告)日：2021-09-21

申请号：US16312167

申请日：2017-08-19

Applicant: Aurea Biolabs Private Limited

Inventor： Sreeraj Gopi ,  Karthik Varma Ayiranazhi Covilakam ,  Joby Jacob

IPC: A61K36/906 ,  A61K36/31 ,  A61K36/736 ,  A61K36/185

Abstract: The present disclosure discloses a herbal formulation in powdered dosage form, which is useful to enhance the physical endurance or strength in athletes. The disclosure also includes a method of preparation of the formulation, which involves the encapsulation of the natural ingredients in a natural matrix. The formulation comprises Moringa oleifera, Kaempferia parviflora and Punica granatum that are processed to obtain the product in powder form by encapsulation of the natural ingredients in a natural matrix. The formulation increased the nitrate and nitrite levels in serum and saliva in human and is useful to improve the general health of the athletes.

公开(公告)号：US20210379139A1

公开(公告)日：2021-12-09

申请号：US17409502

申请日：2021-08-23

Applicant: Aurea Biolabs Private Limited

Inventor： Sreeraj Gopi ,  Karthik Varma Ayiranazhi Covilakam ,  Joby Jacob

IPC: A61K36/906 ,  A61K36/31 ,  A61K36/736 ,  A61K36/185

Abstract: The present disclosure discloses a herbal formulation in powdered dosage form, which is useful to enhance the physical endurance or strength in athletes. The disclosure also includes a method of preparation of the formulation, which involves the encapsulation of the natural ingredients in a natural matrix. The formulation comprises Moringa oleifera, Kaempferia parviflora and Punica granatum that are processed to obtain the product in powder form by encapsulation of the natural ingredients in a natural matrix. The formulation increased the nitrate and nitrite levels in serum and saliva in human and is useful to improve the general health of the athletes.

公开(公告)号：US20190240280A1

公开(公告)日：2019-08-08

申请号：US16312167

申请日：2017-08-19

Applicant: Aurea Biolabs Private Limited

Inventor： Sreeraj Gopi ,  Karthik Varma Ayiranazhi Covilakam ,  Joby Jacob

IPC: A61K36/906 ,  A61K36/31 ,  A61K36/185

CPC classification number: A61K36/906 ,  A61K36/185 ,  A61K36/31 ,  A61K36/736 ,  A61K2236/15 ,  A61K2236/33

Abstract: The present disclosure discloses a herbal formulation in powdered dosage form, which is useful to enhance the physical endurance or strength in athletes. The disclosure also includes a method of preparation of the formulation, which involves the encapsulation of the natural ingredients in a natural matrix. The formulation comprises Moringa oleifera, Kaempferia parviflora and Punica granatum that are processed to obtain the product in powder form by encapsulation of the natural ingredients in a natural matrix. The formulation increased the nitrate and nitrite levels in serum and saliva in human and is useful to improve the general health of the athletes.