Systems and Methods for Remotely Monitoring the Cryogenic Processing of Samples

    公开(公告)号:US20190383554A1

    公开(公告)日:2019-12-19

    申请号:US16463705

    申请日:2017-11-24

    申请人: Asymptote Ltd.

    摘要: A remote system for monitoring and controlling one or more devices for use in the cryogenic processing of a sample is provided. A remote server (130) is provided, capable of transmitting freezing profile data to one or more freezers (101, . . . , 10n), transmitting transportation profile data to one or more transportation devices, and transmitting thawing profile data to one or more thawing devices. The remote server is also capable of receiving detected data from the one or more freezers relating to the freezing of a sample in accordance with the freezing profile data, receiving detected data from the one or more transportation devices relating to the transportation of a sample in accordance with the transportation profile data, and receiving detected data from the one or more thawing machines relating to the thawing of a sample in accordance with the thawing profile data.

    Thawing methods and apparatus
    4.
    发明授权

    公开(公告)号:US11441979B2

    公开(公告)日:2022-09-13

    申请号:US15532815

    申请日:2015-12-04

    申请人: ASYMPTOTE LTD.

    摘要: The invention provides a method of thawing a sample comprised in a container, the method comprising the steps of: a) calculating an agitation program as a function of either or both of the sample volume and the type of the container, and the ice fraction in the sample, and optionally the thermal conductivity of the sample container; b) agitating said sample according to the program to agitate at least one region of the sample; and c) changing the agitation program applied to at least one region of the sample in response to changes in the sample volume and/or sample ice fraction. The invention further provides a method of reducing shearing to cells during a method of agitation, and methods for thawing a sample wherein a sample container is differentially heated. An apparatus for use in the methods is also provided, as is an apparatus for thawing and/or cooling a sample which comprises a resilient vessel wall.