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公开(公告)号：US20240182479A1
公开(公告)日：2024-06-06
申请号：US18500155
申请日：2023-11-02
申请人： AstraZeneca AB
IPC分类号： C07D487/04 , A61P11/06 , A61P37/06
CPC分类号： C07D487/04 , A61P11/06 , A61P37/06
摘要： The present application relates to chemical compounds of Formula (I), and pharmaceutically acceptable salts thereof, that inhibit IRAK4 and consequently have potential utility in medicine.
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公开(公告)号：US20210188821A1
公开(公告)日：2021-06-24
申请号：US17188097
申请日：2021-03-01
申请人： AstraZeneca AB
发明人： Karl Magnus NILSSON , Annika Birgitta Margareta ÅSTRAND , Anna Ingrid Kristina BERGGREN , Johan R. JOHANSSON , Matti Juhani LEPISTÖ , Sameer Pralhad KAWATKAR , Qibin SU , Jason Grant KETTLE
IPC分类号： C07D403/14 , A61P17/14 , A61K9/00
摘要： Disclosed herein are compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R8 have any of the meanings defined herein. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of using the same.
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公开(公告)号：US20240208947A1
公开(公告)日：2024-06-27
申请号：US18538067
申请日：2023-12-13
申请人： AstraZeneca AB
发明人： KARL MAGNUS NILSSON , Annika Birgitta Margareta ÅSTRAND , Anna Ingrid Kristina BERGGREN , Johan R. JOHANSSON , Matti Juhani LEPISTÖ , Sameer Pralhad KAWATKAR , Qibin SU , Jason Grant KETTLE
IPC分类号： C07D403/14 , A61K9/00 , A61P17/14
CPC分类号： C07D403/14 , A61K9/0075 , A61P17/14
摘要： Disclosed herein are compounds of Formula (I),
and pharmaceutically acceptable salts thereof, wherein R1-R8 have any of the meanings defined herein. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of using the same.-
公开(公告)号：US20220185817A1
公开(公告)日：2022-06-16
申请号：US17457249
申请日：2021-12-01
申请人： AstraZeneca AB
IPC分类号： C07D487/04 , A61P11/06 , A61P37/06
摘要： The present application relates to chemical compounds of Formula (I), and pharmaceutically acceptable salts thereof, that inhibit IRAK4 and consequently have potential utility in medicine.
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