Membrane, process and system for isolating virus from solution
    5.
    发明授权
    Membrane, process and system for isolating virus from solution 失效
    从溶液中分离病毒的膜,过程和系统

    公开(公告)号:US5017292A

    公开(公告)日:1991-05-21

    申请号:US521784

    申请日:1990-05-10

    摘要: A composite membrane and process utilizing the membrane which is capable of selectively removing particles such as viral particles from a solution such as a protein solution is provided. The membrane comprises a porous membrane substrate, a surface skin having ultrafiltration separation properties and an intermediate porous zone between the substrate and the skin which intermediate zone has an average pore size smaller than that of the substrate. The intermediate zone is free of voids which break the skin and which directly fluid communicate with the substrate. The composite is capable of a log reduction value of at least 3 (99.9% removal) of particles selectively from solution.

    摘要翻译: 提供一种复合膜和利用该膜的方法,其能够从诸如蛋白质溶液的溶液中选择性地除去诸如病毒颗粒的颗粒。 膜包括多孔膜基底,具有超滤分离性能的表面皮肤和在基底和皮肤之间的中间多孔区,该中间区的平均孔径小于基底的平均孔径。 中间区域没有空隙,其破坏皮肤并且与基底直接流体连通。 复合材料能够从溶液中选择性地减少至少3(99.9%去除)颗粒的对数减少值。