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    Delivery device and related methods
    2.
    发明授权
    Delivery device and related methods 有权

    公开(公告)号：US11103659B2

    公开(公告)日：2021-08-31

    申请号：US13541261

    申请日：2012-07-03

    Applicant: Andrew Jones ,  Richard L. Miller

    Inventor： Andrew Jones ,  Richard L. Miller

    IPC: A61M15/00

    Abstract: A dose delivery device with a mouthpiece having an inlet, an outlet, and an air path extending between the inlet and the outlet. A dose chamber having an opening may hold a dose, e.g., for inhalation by a user. One or more bypass inlets, two or more dispersion chambers, and/or flow arrangements in which incoming and outgoing flow in a dispersion chamber are transverse may be used to disperse a dose for delivery to a user.

    Inhalation device
    6.
    发明授权
    Inhalation device 有权
    吸入装置

    公开(公告)号：US08763605B2

    公开(公告)日：2014-07-01

    申请号：US11491004

    申请日：2006-07-20

    Applicant: Andrew Jones ,  Richard L. Miller

    Inventor： Andrew Jones ,  Richard L. Miller

    IPC: A61M15/00 ,  A61M11/00 ,  A61M11/02

    CPC classification number: A61M15/0045 ,  A61M11/02 ,  A61M15/0003 ,  A61M15/0005 ,  A61M15/001 ,  A61M15/002 ,  A61M15/0021 ,  A61M15/0028 ,  A61M15/0038 ,  A61M15/0043 ,  A61M15/0048 ,  A61M15/0065 ,  A61M15/0075 ,  A61M15/0085 ,  A61M2202/064 ,  A61M2205/07

    Abstract: The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.

    Abstract translation: 本发明提供将药物分散方法整合到药物或药物递送系统中。 使用的药物分散方法包括剪切（例如，具有或不具有气体辅助的药物的空气），毛细管流动或文丘里效应，诸如旋转，振动或冲击的机械手段和湍流（例如，使用筛网， 或限制在空中路径）。 这些药物分散方法允许释放系统中的所有药物，从而控制剂量大小。 这些方法还提供了药物计量，流化，夹带，解聚和解聚。 本发明还提供了将药物密封系统整合到装置中。 药物密封系统提供了阻止药物从包装的一个区域迁移到另一个区域的方式。 药物密封系统还可以提供紧密包含药物的方法，直到包装打开为止，在包装/装置制造过程中引导气流通过包装并管理和容纳药物。

    DELIVERY DEVICE AND RELATED METHODS
    7.
    发明申请
    DELIVERY DEVICE AND RELATED METHODS 审中-公开
    交付设备及相关方法

    公开(公告)号：US20130008442A1

    公开(公告)日：2013-01-10

    申请号：US13541261

    申请日：2012-07-03

    Applicant: Andrew Jones ,  Richard L. Miller

    Inventor： Andrew Jones ,  Richard L. Miller

    IPC: A61M15/00

    CPC classification number: A61M15/0028 ,  A61M15/0035 ,  A61M2202/064 ,  A61M2206/16

    Abstract: A dose delivery device with a mouthpiece having an inlet, an outlet, and an air path extending between the inlet and the outlet. A dose chamber having an opening may hold a dose, e.g., for inhalation by a user. One or more bypass inlets, two or more dispersion chambers, and/or flow arrangements in which incoming and outgoing flow in a dispersion chamber are transverse may be used to disperse a dose for delivery to a user.

    Abstract translation: 具有口部的剂量递送装置，其具有在入口和出口之间延伸的入口，出口和空气路径。 具有开口的剂量室可以保持剂量，例如用于用户的吸入。 可以使用一个或多个旁路入口，两个或更多个分散室和/或其中分散室中的进入和流出是横向的流动装置来分散用于递送给使用者的剂量。

    Sealed capsule including an integrated puncturing mechanism
    8.
    发明授权
    Sealed capsule including an integrated puncturing mechanism 有权
    密封胶囊包括集成的穿刺机构

    公开(公告)号：US08342176B2

    公开(公告)日：2013-01-01

    申请号：US12973095

    申请日：2010-12-20

    Applicant: Andrew Jones ,  Richard L. Miller

    Inventor： Andrew Jones ,  Richard L. Miller

    IPC: A61M11/00

    CPC classification number: A61M15/0028 ,  A61K9/0075 ,  A61K9/4808 ,  A61M15/0036 ,  A61M2202/064

    Abstract: A sealed self-piercing capsule for storing and delivering a substance, such as a medicine, comprises one or more barrier layers forming a sealed chamber for containing the substance. An internal puncturing mechanism is disposed within the capsule chamber for puncturing a barrier layer to release the substance from the chamber. The internal puncturing mechanism may comprise a sharpened edge located on a movable tube, which moves relative to a barrier layer forming the sealed chamber to puncture the barrier layer.

    Abstract translation: 用于储存和输送诸如药物的物质的密封自穿孔胶囊包括形成用于容纳物质的密封室的一个或多个阻隔层。 内部穿刺机构设置在胶囊室内，用于刺穿阻挡层以从腔室释放物质。 内部穿刺机构可以包括位于可动管上的锋利边缘，其相对于形成密封室的阻挡层移动以刺穿阻挡层。

    Sealed capsule including an integrated puncturing mechanism
    9.
    发明授权
    Sealed capsule including an integrated puncturing mechanism 有权
    密封胶囊包括集成的穿刺机构

    公开(公告)号：US07861712B2

    公开(公告)日：2011-01-04

    申请号：US10831381

    申请日：2004-04-23

    Applicant: Andrew Jones ,  Richard L. Miller

    Inventor： Andrew Jones ,  Richard L. Miller

    IPC: A61M11/00

    CPC classification number: A61M15/0028 ,  A61K9/0075 ,  A61K9/4808 ,  A61M15/0036 ,  A61M2202/064

    Abstract: A sealed self-piercing capsule for storing and delivering a substance, such as a medicine, comprises one or more barrier layers forming a sealed chamber for containing the substance. An internal puncturing mechanism is disposed within the capsule chamber for puncturing a barrier layer to release the substance from the chamber. The internal puncturing mechanism may comprise a sharpened edge located on a movable tube, which moves relative to a barrier layer forming the sealed chamber to puncture the barrier layer.

    Abstract translation: 用于储存和输送诸如药物的物质的密封自穿孔胶囊包括形成用于容纳物质的密封室的一个或多个阻隔层。 内部穿刺机构设置在胶囊室内，用于刺穿阻挡层以从腔室释放物质。 内部穿刺机构可以包括位于可动管上的锋利边缘，其相对于形成密封室的阻挡层移动以刺穿阻挡层。

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