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公开(公告)号:US20070099200A1
公开(公告)日:2007-05-03
申请号:US11412055
申请日:2006-04-25
申请人: Andrea Chow , John Owicki , J. Parce
发明人: Andrea Chow , John Owicki , J. Parce
IPC分类号: C12Q1/68 , C12M3/00 , G01N33/557
CPC分类号: G01N33/557 , B01L3/50273 , B01L3/502753 , B01L7/52 , B01L2200/10 , B01L2300/0816 , B01L2300/1822 , B01L2300/1833 , B01L2400/0415 , B01L2400/0421 , B01L2400/0487 , G01N27/44791 , G01N33/5306
摘要: The present invention provides novel microfluidic devices and methods for performing pulsed field mobility shift assays in microfluidic devices. In particular the devices and methods of the invention utilize differences between electrophoretic mobilities (e.g., as between reactants and products, especially in non-fluorogenic reactions) in order to separate the species and thus analyze the reaction.
摘要翻译: 本发明提供了用于在微流体装置中进行脉冲场迁移率变动测定的新型微流体装置和方法。 特别地,本发明的装置和方法利用电泳迁移率之间的差异(例如,在反应物和产物之间,特别是在非荧光反应中),以便分离物种并因此分析反应。
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公开(公告)号:US20070264634A1
公开(公告)日:2007-11-15
申请号:US10683583
申请日:2003-10-09
申请人: Larry Bock , R. Daniels , Stephen Empedocles , Chumming Niu , John Owicki , Vijendra Sahi , Calvin Chow , George Pontis
发明人: Larry Bock , R. Daniels , Stephen Empedocles , Chumming Niu , John Owicki , Vijendra Sahi , Calvin Chow , George Pontis
CPC分类号: G01N27/4146 , B82Y5/00 , C12Q1/001 , C12Q1/6825 , G01N33/54366 , Y10T436/144444
摘要: Methods of detecting a component of interest, a change in charge, a pH, a cellular response using nanosensors are provided. Nanosensors, including nanowires and nanowire arrays comprising functionalized and/or non-functionalized nanowires are provided. Nanosensors are, used for detection in cellular fragmentation, multiple concentration analysis, glucose detection, and intracellular analysis.
摘要翻译: 提供了检测感兴趣的组分,电荷变化,pH,使用纳米传感器的细胞反应的方法。 提供纳米传感器,包括纳米线和包含官能化和/或非官能化纳米线的纳米线阵列。 纳米传感器用于细胞分裂检测,多重浓度分析,葡萄糖检测和细胞内分析。
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公开(公告)号:US20080044911A1
公开(公告)日:2008-02-21
申请号:US11874412
申请日:2007-10-18
申请人: Larry Bock , R. Daniels , Stephen Empedocles , John Owicki
发明人: Larry Bock , R. Daniels , Stephen Empedocles , John Owicki
CPC分类号: G01N27/4146 , B82Y5/00 , C12Q1/001 , C12Q1/6825 , G01N33/54366 , Y10T436/144444
摘要: Methods of detecting a component of interest, a change in charge, a pH, a cellular response using nanosensors are provided. Nanosensors, including nanowires and nanowire arrays comprising functionalized and/or non-functionalized nanowires are provided. Nanosensors are used for detection in cellular fragmentation, multiple concentration analysis, glucose detection, and intracellular analysis.
摘要翻译: 提供了检测感兴趣的组分,电荷变化,pH,使用纳米传感器的细胞反应的方法。 提供纳米传感器,包括纳米线和包含官能化和/或非官能化纳米线的纳米线阵列。 纳米传感器用于细胞分裂,多重浓度分析,葡萄糖检测和细胞内分析中的检测。
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