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公开(公告)号：US06640597B2
公开(公告)日：2003-11-04
申请号：US10003231
申请日：2001-12-06
申请人： Alexander Beeck , Christoph Nagler , Mark Richter
发明人： Alexander Beeck , Christoph Nagler , Mark Richter
IPC分类号： B21D102
CPC分类号： F01D5/186 , B23P9/00 , B23P2700/06 , F05D2230/10 , F05D2230/90 , F05D2250/25 , Y10T29/47
摘要： A method is disclosed for reducing the variance in the coolant consumption of components of a turbo-machine, in particular a gas turbine. The components are provided with one or more holes for the passage of a coolant, wherein a surface roughness existing inside the holes is reduced by mechanical finishing. The method is characterized by mechanical finishing that is performed by reshaping rough points that cause the surface roughness using a cold working process such as at least one of beating, pressing and rolling. The method permits a simple reduction of the surface roughness without creating finishing residues that could result in obstructions of the holes.
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公开(公告)号：US06565317B2
公开(公告)日：2003-05-20
申请号：US09820679
申请日：2001-03-30
申请人： Alexander Beeck , Christoph Nagler , Mark Richter , Klaus Semmler , Lothar Schneider , Joerg Stengele
发明人： Alexander Beeck , Christoph Nagler , Mark Richter , Klaus Semmler , Lothar Schneider , Joerg Stengele
IPC分类号： F01D518
CPC分类号： B22C9/103 , F01D5/187 , F01D25/12 , F05D2240/81 , F05D2260/201 , F05D2260/202
摘要： A platelike projecting component portion of a component used in gas turbines or other similar applications includes a surface upon which hot gas acts and cooling bores through which a cooling medium is capable of flowing. Effective cooling is achieved by providing at least one plenum assigned solely to the component portion. The plenum is arranged so as to be directly adjacent to the surface upon which hot gas acts and through which the cooling medium is capable of flowing to provide convective heat transfer. The cooling bores are designed as blow-out orifices which emanate from the plenum and issue the cooling medium onto the surface upon which hot gas acts, thereby forming a cooling film.
摘要翻译： 用于燃气轮机或其它类似应用中的部件的板状突出部件部分包括热气体作用的表面和冷却孔，冷却介质能通过冷却孔流动。 通过提供仅分配给部件部分的至少一个增压室来实现有效的冷却。 气室被布置成直接邻近热气体所在的表面，并且冷却介质能通过该气体流动以提供对流热传递。 冷却孔被设计为从气室排出的吹出孔，并将冷却介质发放到热气体作用的表面上，由此形成冷却膜。
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公开(公告)号：US20130328310A1
公开(公告)日：2013-12-12
申请号：US13489708
申请日：2012-06-06
IPC分类号： F01D15/10
摘要： Systems and methods for combined flow control and electricity generation are described. Various embodiments may comprise an energy recovery device adapted to produce an electric current. At least a portion of the electric current may be used to power a pump. A control system may be adapted to adjust operating parameters of the system to stabilize or maximize the efficiency of the energy recovery device.
摘要翻译： 描述了用于组合流量控制和发电的系统和方法。 各种实施例可以包括适于产生电流的能量回收装置。 可以使用至少一部分电流来为泵供电。 控制系统可以适于调整系统的操作参数以稳定或最大化能量回收装置的效率。
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4.发明授权公开(公告)号：US08742604B2
公开(公告)日：2014-06-03
申请号：US13489708
申请日：2012-06-06
IPC分类号： F01K25/02
摘要： Systems and methods for combined flow control and electricity generation are described. Various embodiments may include an energy recovery device adapted to produce an electric current. At least a portion of the electric current may be used to power a pump. A control system may be adapted to adjust operating parameters of the system to stabilize or maximize the efficiency of the energy recovery device.
摘要翻译： 描述了用于组合流量控制和发电的系统和方法。 各种实施例可以包括适于产生电流的能量回收装置。 可以使用至少一部分电流来为泵供电。 控制系统可以适于调整系统的操作参数以稳定或最大化能量回收装置的效率。
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公开(公告)号：US07781566B2
公开(公告)日：2010-08-24
申请号：US12625650
申请日：2009-11-25
申请人： Mark I. Greene , Ramachandran Murali , Hongtao Zhang , Mark Richter , Alan Berezov , Qingdu Liu , Jinqiu Chen
发明人： Mark I. Greene , Ramachandran Murali , Hongtao Zhang , Mark Richter , Alan Berezov , Qingdu Liu , Jinqiu Chen
CPC分类号： C07K14/71 , A61K38/00 , A61K39/00 , A61K39/0011 , A61K47/48238 , A61K47/4833 , A61K47/48384 , A61K47/48407 , A61K47/48507 , A61K47/62 , A61K47/646 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K51/10 , C07K7/06 , C07K7/08 , C07K14/7151 , C07K14/82
摘要： Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are disclosed.
摘要翻译： 描述了erbB，TNF和IgSF受体的肽，模拟物和抗体以及包含其的药物组合物。 公开了在治疗，预防，成像和诊断应用中使用这些抗体，肽和模拟物的方法。
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6.发明申请MONOCLONAL ANTIBODIES TO ACTIVATED ERBB FAMILY MEMBERS AND METHODS OF USE 审中-公开活化ERBB家族成员的单克隆抗体及其使用方法公开(公告)号：US20100189649A1
公开(公告)日：2010-07-29
申请号：US12651527
申请日：2010-01-04
IPC分类号： A61K39/395 , C07K16/00 , A61K49/00 , A61P35/00
CPC分类号： C07K14/71 , A61K38/00 , A61K39/00 , A61K47/62 , A61K47/646 , C07K14/7151 , C07K14/82
摘要： Antibodies which bind to activated members of the erbB, TNF, and IgSF family of receptors and pharmaceutical compositions comprising the same are disclosed. Peptides and mimetics of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are also described. Methods of using such antibodies, peptides, and mimetics in tumor therapeutic, prophylactic, imaging and diagnostic applications are disclosed.
摘要翻译： 公开了结合erbB，TNF和IgSF受体家族的活化成员的抗体和包含其的药物组合物的抗体。 还描述了erbB，TNF和IgSF受体的肽和模拟物以及包含其的药物组合物。 公开了在肿瘤治疗，预防，成像和诊断应用中使用这些抗体，肽和模拟物的方法。
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7.发明申请Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers 审中-公开测定采用电化学发光标记和电化学发光淬灭剂公开(公告)号：US20060035248A1
公开(公告)日：2006-02-16
申请号：US11124407
申请日：2005-05-09
IPC分类号： C12Q1/68
CPC分类号： G01N33/542 , C09B57/10 , C09B69/109 , G01N33/582
摘要： This invention pertains to the general field of chemical and biological assays which employ electrochemiluminescence (ECL), also referred to as electrogenerated chemiliminescence. More particularly, the present invention pertains to certain classes of chemical moieties which strongly quench ECL, and the use of these ECL quenchers in combination with ECL labels, for example, in ECL assay methods which employ an ECL quencher and an ECL label. One class of such quenching moieties are those which comprise at least one benzene moiety. Sub-classes of such quenching moieties are those which comprise at least one phenol moiety, quinone moiety, benzene carboxylic acid, and/or benzene carboxylate moiety.
摘要翻译： 本发明涉及使用电化学发光（ECL）的化学和生物测定的一般领域，也被称为电生化学发光。 更具体地说，本发明涉及强烈猝灭ECL的某些类别的化学部分，以及这些ECL猝灭剂与ECL标记的组合的使用，例如在采用ECL猝灭剂和ECL标记的ECL测定方法中。 一类这样的猝灭部分是包含至少一个苯部分的那些。 这种猝灭部分的亚类是包含至少一个苯酚部分，醌部分，苯羧酸和/或苯羧酸酯部分的那些。
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公开(公告)号：US08326643B1
公开(公告)日：2012-12-04
申请号：US11511593
申请日：2006-08-28
IPC分类号： G06Q10/00
摘要： A system for providing phone conversation analysis may comprise at least one subsystem that monitors a phone conversation for key words or key phrases as defined by business rules. Conversations containing such words may be tagged with appropriate metadata to identify the conversation for subsequent analysis, and for conducting trending and analysis of the collected data. Also, a system for providing phone conversation analysis may comprise subsystems for monitoring a phone conversation for key words or key phrases, and associating the key words or key phrases with pre-determined offers or services.
摘要翻译： 用于提供电话会话分析的系统可以包括至少一个子系统，其监视由业务规则定义的关键词或关键短语的电话对话。 包含这些单词的对话可以用适当的元数据标记，以识别用于后续分析的对话，以及对收集的数据进行趋势和分析。 此外，用于提供电话会话分析的系统可以包括用于监视关键词或关键短语的电话对话的子系统，以及将关键词或关键短语与预定的报价或服务相关联。
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公开(公告)号：US20100120688A1
公开(公告)日：2010-05-13
申请号：US12625706
申请日：2009-11-25
申请人： Mark I. Greene , Ramachandran Murali , Hongtao Zhang , Mark Richter , Alan Berezov , Qingdu Liu , Jinqiu Chen
发明人： Mark I. Greene , Ramachandran Murali , Hongtao Zhang , Mark Richter , Alan Berezov , Qingdu Liu , Jinqiu Chen
CPC分类号： C07K14/71 , A61K38/00 , A61K39/00 , A61K39/0011 , A61K47/48238 , A61K47/4833 , A61K47/48384 , A61K47/48407 , A61K47/48507 , A61K47/62 , A61K47/646 , A61K47/6803 , A61K47/6809 , A61K47/6835 , A61K51/10 , C07K7/06 , C07K7/08 , C07K14/7151 , C07K14/82
摘要： Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are disclosed.
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10.发明授权Monoclonal antibodies to activated erbB family members and methods of use thereof 有权活化的erbB家族成员的单克隆抗体及其使用方法公开(公告)号：US07662374B2
公开(公告)日：2010-02-16
申请号：US10213292
申请日：2002-08-05
IPC分类号： A61K39/395 , C12P21/08 , C07K16/28 , G01N33/53 , G01N33/534 , G01N33/574
CPC分类号： C07K14/71 , A61K38/00 , A61K39/00 , A61K47/62 , A61K47/646 , C07K14/7151 , C07K14/82
摘要： Antibodies which bind to activated members of the erbB, TNF, and IgSF family of receptors and pharmaceutical compositions comprising the same are disclosed. Peptides and mimetics of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are also described. Methods of using such antibodies, peptides, and mimetics in tumor therapeutic, prophylactic, imaging and diagnostic applications are disclosed.
摘要翻译： 公开了结合erbB，TNF和IgSF受体家族的活化成员的抗体和包含其的药物组合物的抗体。 还描述了erbB，TNF和IgSF受体的肽和模拟物以及包含其的药物组合物。 公开了在肿瘤治疗，预防，成像和诊断应用中使用这些抗体，肽和模拟物的方法。
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