公开(公告)号：US20230100871A1

公开(公告)日：2023-03-30

申请号：US17953246

申请日：2022-09-26

Applicant: Agilent Technologies, Inc.

Inventor： Daniell Malsch ,  Christoph Keppler ,  Bertram Beigel ,  Karsten Kraiczek

IPC: G01N30/74 ,  G01N30/38 ,  G01N30/14

Abstract: A flow cell, for detecting a fluidic sample separated by a sample separation apparatus, includes a cuvette, a flow channel formed at least partially in the cuvette and configured to enable a flow of the separated fluidic sample through the flow channel, an electromagnetic radiation inlet at which an excitation electromagnetic radiation beam is couplable into the cuvette, and an electromagnetic radiation outlet at which an emission electromagnetic radiation beam, generated by an interaction between the excitation electromagnetic radiation beam and the separated fluidic sample, is couplable out of the cuvette. A geometry of the cuvette is configured so that at least one point at the excitation backside surface of the cuvette is outside of a direct field of view of the electromagnetic radiation outlet.

公开(公告)号：US20160363568A1

公开(公告)日：2016-12-15

申请号：US15241786

申请日：2016-08-19

Applicant: Agilent Technologies, Inc.

Inventor： Kevin P. Killeen ,  Hubert Kuderer ,  Karsten Kraiczek

IPC: G01N30/74 ,  G01N21/05 ,  G01N21/31

CPC classification number: G01N30/74 ,  G01J2003/102 ,  G01N21/05 ,  G01N21/31 ,  G01N2021/0346 ,  G01N2021/3129 ,  G01N2021/3133 ,  G01N2021/3148 ,  G01N2021/317 ,  G01N2030/027 ,  G01N2201/06153 ,  G01N2201/0627 ,  G01N2201/0638

Abstract: A fluid separation system for separating compounds of a sample fluid in a mobile phase comprises a detector adapted to detect separated compounds by providing an optical stimulus signal to the sample fluid and receiving a response signal on the optical stimulus signal. The detector comprises a light source adapted to provide an output light beam as the optical stimulus signal. The light source comprises a plurality of light emitting elements each adapted to emit a light beam having a respective wavelength, and a diffracting element. The plurality of light emitting elements are arranged that emitted light beams impinging on the diffracting element in a respective angle dependent on the respective wavelength are diffracted by the diffracting element into the output light beam.

Abstract translation: 用于分离流动相中样品流体的化合物的流体分离系统包括适于通过向样品流体提供光刺激信号并且在光刺激信号上接收响应信号来检测分离的化合物的检测器。 检测器包括适于提供输出光束作为光刺激信号的光源。 光源包括多个适于发射具有各自波长的光束的发光元件和衍射元件。 多个发光元件被布置成使得衍射元件以相应的角度照射在衍射元件上的发射光束被衍射元件衍射成输出光束。

公开(公告)号：US20140373606A1

公开(公告)日：2014-12-25

申请号：US14376430

申请日：2012-02-03

Applicant: AGILENT TECHNOLOGIES, INC.

Inventor： Karsten Kraiczek ,  John Mannion ,  Kevin P. Killeen

IPC: G01N21/05 ,  B32B37/18 ,  B32B38/10 ,  G01N30/74

CPC classification number: G01N21/05 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0838 ,  B32B37/18 ,  B32B38/10 ,  B32B2551/00 ,  G01N30/74 ,  G01N33/54373 ,  G01N2021/0346 ,  G01N2021/052 ,  G01N2021/056 ,  G01N2030/027 ,  G01N2030/746 ,  G01N2201/08 ,  Y10T156/10

Abstract: A micromachined flow cell (100), comprising a substrate (102), and a freestanding tube (104) delimiting a fluidic conduit (800) therein and being integrally formed from material of the substrate (102).

Abstract translation: 一种微加工流动池（100），包括基底（102）和在其中限定流体导管（800）并由基底（102）的材料一体形成的独立管（104）。