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    Single channel cartridge device for coagulation assays in fluid samples
    3.
    发明授权
    Single channel cartridge device for coagulation assays in fluid samples 有权

    公开(公告)号：US10598675B2

    公开(公告)日：2020-03-24

    申请号：US16150818

    申请日：2018-10-03

    申请人： Abbott Point of Care Inc.

    发明人： Katrina Petronilla Di Tullio ,  Jay Kendall Taylor ,  Niko Daniel Lee-Yow ,  Sheila Diane Ball

    IPC分类号： G01N33/86 ,  G01N31/00 ,  B01L3/00 ,  G01N33/49 ,  G01N27/403 ,  G01N27/416

    摘要： The present invention relates to analytical testing devices comprising a single channel with micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using a single channel with micro-environment sensors in a point of care test cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample and a conduit fluidically connected to the inlet chamber. The conduit includes a sensor chip including a first micro-environment sensor and a second microenvironment sensor, and a fluid lock valve. The sample analysis cartridge further includes a pump configured to push the biological sample over the first micro-environment sensor and the second microenvironment sensor to the fluidic lock valve such that the biological sample is positioned over the first micro-environment sensor and the second micro-environment sensor.

    SINGLE CHANNEL CARTRIDGE DEVICE FOR COAGULATION ASSAYS IN FLUID SAMPLES
    4.
    发明申请
    SINGLE CHANNEL CARTRIDGE DEVICE FOR COAGULATION ASSAYS IN FLUID SAMPLES 审中-公开

    公开(公告)号：US20190033331A1

    公开(公告)日：2019-01-31

    申请号：US16150818

    申请日：2018-10-03

    申请人： Abbott Point of Care Inc.

    发明人： Katrina Petronilla Di Tullio ,  Jay Kendall Taylor ,  Niko Daniel Lee-Yow ,  Sheila Diane Ball

    IPC分类号： G01N33/86 ,  G01N33/49 ,  B01L3/00 ,  G01N27/416 ,  G01N27/403

    摘要： The present invention relates to analytical testing devices comprising a single channel with micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using a single channel with micro-environment sensors in a point of care test cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample and a conduit fluidically connected to the inlet chamber. The conduit includes a sensor chip including a first micro-environment sensor and a second microenvironment sensor, and a fluid lock valve. The sample analysis cartridge further includes a pump configured to push the biological sample over the first micro-environment sensor and the second microenvironment sensor to the fluidic lock valve such that the biological sample is positioned over the first micro-environment sensor and the second micro-environment sensor.

    CARTRIDGE DEVICE WITH SEGMENTED FLUIDICS FOR ASSAYING COAGULATION IN FLUID SAMPLES
    8.
    发明申请
    CARTRIDGE DEVICE WITH SEGMENTED FLUIDICS FOR ASSAYING COAGULATION IN FLUID SAMPLES 审中-公开
    具有分离流体的液体装置用于测定流体样品中的凝血

    公开(公告)号：US20160091509A1

    公开(公告)日：2016-03-31

    申请号：US14866402

    申请日：2015-09-25

    申请人： Abbott Point of Care Inc.

    发明人： Katrina Petronilla Di Tullio ,  Jay Kendall Taylor ,  John Lewis Emerson Campbell ,  Caglar Elbuken ,  Shelia Diane Ball ,  Noam Saul Lightstone

    IPC分类号： G01N33/86 ,  B01L3/00

    CPC分类号： G01N33/86 ,  B01L3/5027 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0633 ,  B01L2400/0672 ,  B01L2400/0688 ,  B01L2400/0694 ,  G01N2333/745 ,  G01N2333/974

    摘要： The present invention relates to analytical testing devices comprising segmented fluidics and methods for assaying coagulation in a fluid sample received within the segmented fluidics. For example, the present invention may be directed to sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a first flow restrictor region, a second reagent, and a second sensor region. The sample analysis cartridge further includes a pump configured to independently mix the first segment in the second conduit and the second segment in the third conduit, and independently position the first segment over the first sensor region and position the second segment over the second sensor region.

    摘要翻译： 本发明涉及包括分段流体学的分析测试装置和用于分析在分段流体学中接收的流体样品中的凝结的方法。 例如，本发明可以涉及包括入口室的样品分析盒，包括构造成将生物样品分成至少第一和第二段的第一接头的第一导管，包括第一试剂的第二导管，第一传感器 区域和第一流体锁定阀，以及包括第一限流器区域，第二试剂和第二传感器区域的第三导管。 样品分析盒还包括被配置为独立地混合第二导管中的第一片段和第三导管中的第二片段的泵，并且将第一片段独立地定位在第一传感器区域上并将第二片段定位在第二传感器区域上。