-
公开(公告)号：US20180298003A1
公开(公告)日：2018-10-18
申请号：US16018357
申请日：2018-06-26
申请人： AbbVie Inc.
发明人： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC分类号： C07D471/22 , C07D471/16
摘要： The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
-
公开(公告)号：US09957263B2
公开(公告)日：2018-05-01
申请号：US14392201
申请日：2014-06-27
申请人： AbbVie Inc.
发明人： Yujia Dai , Steven D. Fidanze , Lisa Hasvold , James Holms , Dachun Liu , William McClellan , Keith McDaniel , Jasmina Marjanovic , George Sheppard , Le Wang
IPC分类号： C07D471/02 , A61K31/44 , A61K31/497 , C07D471/04 , A61K45/06 , A61K31/437 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K31/4545 , A61K31/506
CPC分类号： C07D471/04 , A61K31/437 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K45/06
摘要： Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided. The compounds are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Pharmaceutical compositions comprised of one or more compounds of formula (I) are also provided.
-
公开(公告)号：US20160272630A1
公开(公告)日：2016-09-22
申请号：US14392201
申请日：2014-06-27
申请人： ABBVIE INC.
发明人： Yujia Dai , Steven D. Fidanze , Lisa Hasvold , James Holms , Dachun Liu , William McClellan , Keith McDaniel , Jasmina Marjanovic , George Sheppard , Le Wang
IPC分类号： C07D471/04 , A61K31/4545 , A61K31/5377 , A61K31/541 , A61K31/497 , A61K31/506 , A61K31/551 , A61K31/437 , A61K31/496
CPC分类号： C07D471/04 , A61K31/437 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K45/06
摘要： Compounds of formula (I) and pharmaceutically acceptable salts thereof are provided. The compounds are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Pharmaceutical compositions comprised of one or more compounds of formula (I) are also provided.
-
公开(公告)号：US20200291027A1
公开(公告)日：2020-09-17
申请号：US16827026
申请日：2020-03-23
申请人： AbbVie Inc.
发明人： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC分类号： C07D471/22 , A61P15/16 , A61P31/18 , A61P13/12 , A61P35/00 , C07D471/16
摘要： The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
-
公开(公告)号：US20190084981A1
公开(公告)日：2019-03-21
申请号：US16192927
申请日：2018-11-16
申请人： AbbVie Inc.
发明人： Yujia Dai , Steven D. Fidanze , Lisa Hasvold , James Holms , Dachun Liu , William McClellan , Keith McDaniel , Jasmina Marjanovic , George Sheppard , Le Wang
IPC分类号： C07D471/04 , A61K45/06 , A61K31/506 , A61K31/497 , A61K31/437 , A61K31/551 , A61K31/541 , A61K31/5377 , A61K31/496 , A61K31/4545
摘要： The present invention provides for compounds of formula (I) wherein Rx, Ry, Rx1, L1, G1, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
-
公开(公告)号：US20210070756A1
公开(公告)日：2021-03-11
申请号：US17099133
申请日：2020-11-16
申请人： AbbVie Inc.
发明人： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC分类号： C07D471/22 , A61P15/16 , A61P31/18 , A61P13/12 , A61P35/00 , C07D471/16
摘要： The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
-
公开(公告)号：US20190389861A1
公开(公告)日：2019-12-26
申请号：US16254124
申请日：2019-01-22
申请人： AbbVie Inc.
发明人： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC分类号： C07D471/22 , C07D471/16
摘要： The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
-
公开(公告)号：US20160185769A1
公开(公告)日：2016-06-30
申请号：US14392200
申请日：2014-05-13
申请人： ABBVIE INC.
发明人： Yujia Dai , Steven D. Fidanze , Lisa Hasvold , James Holms , Dachun Liu , William McClellan , Keith McDaniel , Jasmina Marjanovic , George Sheppard , Le Wang
IPC分类号： C07D471/04 , A61K31/541 , A61K31/496 , A61K31/551 , A61K31/437 , A61K31/5377
CPC分类号： C07D471/04 , A61K31/437 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K45/06
摘要： The present invention provides for compounds of formula (I). wherein Rx, Ry, Rx1, L1, G1, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
摘要翻译： 本发明提供式（I）化合物。 其中Rx，Ry，Rx1，L1，G1，A1，A2，A3和A4具有说明书中定义的任何值及其药学上可接受的盐，其可用作治疗疾病和病症（包括炎症 疾病，癌症和艾滋病。 还提供了由一种或多种式（I）化合物组成的药物组合物。
-
公开(公告)号：US20160039821A1
公开(公告)日：2016-02-11
申请号：US14774866
申请日：2014-03-12
申请人： ABBVIE INC.
发明人： Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
IPC分类号： C07D471/22 , C07D471/16
CPC分类号： C07D471/22 , C07D471/16
摘要： The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3 and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
摘要翻译： 本发明提供式（I）化合物，其中R1，R2，R6，Y1，Y2，Y3，A1，A2，A3和A4具有说明书中定义的任何值及其药学上可接受的盐，其是有用的 作为治疗疾病和病症的药剂，包括炎性疾病，癌症和AIDS。 还提供了包含一种或多种式（I）化合物的药物组合物。
-
公开(公告)号：US10131657B2
公开(公告)日：2018-11-20
申请号：US14392200
申请日：2014-05-13
申请人： AbbVie Inc.
发明人： Yujia Dai , Steven D. Fidanze , Lisa Hasvold , James Holms , Dachun Liu , William McClellan , Keith McDaniel , Jasmina Marjanovic , George Sheppard , Le Wang
IPC分类号： A61K31/437 , A61K31/454 , A61K31/4545 , C07D471/04 , A61K45/06 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K31/551 , A61K31/497 , A61K31/506
摘要： The present invention provides for compounds of formula (I). wherein Rx, Ry, Rx1, L1, G1, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).
-
-
-
-
-
-
-
-
-
搜索结果
12 条记录 (耗时 0.034 秒)
