- 专利标题: TETRACYCLIC BROMODOMAIN INHIBITORS
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申请号: US17099133申请日: 2020-11-16
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公开(公告)号: US20210070756A1公开(公告)日: 2021-03-11
- 发明人: Steven D. Fidanze , Dachun Liu , Robert A. Mantei , Keith F. McDaniel , John Pratt , George S. Sheppard , Le Wang , Andrew Bogdan , James H. Holms , Justin D. Dietrich , Jasmina Marjanovic , Lisa A. Hasvold , Yujia Dai
- 申请人: AbbVie Inc.
- 申请人地址: US IL North Chicago
- 专利权人: AbbVie Inc.
- 当前专利权人: AbbVie Inc.
- 当前专利权人地址: US IL North Chicago
- 主分类号: C07D471/22
- IPC分类号: C07D471/22 ; A61P15/16 ; A61P31/18 ; A61P13/12 ; A61P35/00 ; C07D471/16
摘要:
The present invention provides for compounds of formula (I) wherein R1, R2, R6, Y1, Y2, Y3, A1, A2, A3, and A4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising one or more compounds of formula (I).
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