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公开(公告)号：US20140288082A1
公开(公告)日：2014-09-25
申请号：US14296016
申请日：2014-06-04
发明人： Dong Zou , Wei-Sheng Huang , R. Mathew Thomas , Jan Antoinette C. Romero , Jiwei Qi , Yihan Wang , Xiaotian Zhu , William C. Shakespeare , Rajeswari Sundaramoorthi , Chester A. Metcalf, III , David C. Dalgarno , Tomi K. Sawyer
IPC分类号： C07D487/04 , C07D471/04
CPC分类号： C07D471/04 , C07D473/34 , C07D487/04
摘要： This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
摘要翻译： 本发明涉及以下通式的化合物：其中可变基团如本文所定义，以及其制备和用途。
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公开(公告)号：US20130225528A1
公开(公告)日：2013-08-29
申请号：US13843055
申请日：2013-03-15
发明人： Yihan Wang , Wei-Sheng Huang , Shuangying Liu , William C. Shakespeare , R. Mathew Thomas , Jiwei Qi , Feng Li , Xiaotian Zhu , Anna Kohlmann , David C. Dalgarno , Jan Antoinette C. Romero , Dong Zou
IPC分类号： C07F9/6512 , C07F9/6584
CPC分类号： C07F9/6512 , C07F9/5765 , C07F9/58 , C07F9/650905 , C07F9/6521 , C07F9/65218 , C07F9/65583 , C07F9/65586 , C07F9/6561 , C07F9/65616 , C07F9/65685 , C07F9/657172 , C07F9/6584
摘要： The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
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公开(公告)号：US09273077B2
公开(公告)日：2016-03-01
申请号：US13842951
申请日：2013-03-15
发明人： Yihan Wang , Wei-Sheng Huang , Shuangying Liu , William C. Shakespeare , R. Mathew Thomas , Jiwei Qi , Feng Li , Xiaotian Zhu , Anna Kohlmann , David C. Dalgarno , Jan Antoinette C. Romero , Dong Zou
IPC分类号： A61K31/505 , C07F9/6558 , C07F9/6512 , C07F9/6561 , C07F9/6584 , C07F9/6509 , C07F9/58 , C07F9/60 , C07F9/6521 , C07F9/6568 , C07F9/6571
CPC分类号： C07F9/6584 , C07F9/58 , C07F9/60 , C07F9/650905 , C07F9/6512 , C07F9/6521 , C07F9/65583 , C07F9/65586 , C07F9/6561 , C07F9/65616 , C07F9/65685 , C07F9/657172
摘要： The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use as protein kinase inhibitors.
摘要翻译： 本发明具有以下通式的化合物：其中可变基团如本文所定义，以及其作为蛋白激酶抑制剂的制备和用途。
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公开(公告)号：US20130196979A1
公开(公告)日：2013-08-01
申请号：US13801619
申请日：2013-03-13
发明人： Dong Zou , Wei-Sheng Huang , R. Mathew Thomas , Jan Antoinette C. Romero , Jiwei Qi , Yihan Wang , Xiaotian Zhu , William C. Shakespeare , Rajeswari Sundaramoorthi , Chester A. Metcalf, III , David C. Dalgarno , Tomi K. Sawyer
IPC分类号： C07D487/04 , C07D471/04
CPC分类号： C07D471/04 , C07D473/34 , C07D487/04
摘要： This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
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公开(公告)号：US20200231588A1
公开(公告)日：2020-07-23
申请号：US16722881
申请日：2019-12-20
发明人： Dong Zou , Wei-Sheng Huang , R. Mathew Thomas , Jan Antoinette C. Romero , Jiwei Qi , Yihan Wang , Xiaotian Zhu , William C. Shakespeare , Rajeswari Sundaramoorthi , Chester A. Metcalf, III , David C. Dalgarno , Tomi K. Sawyer
IPC分类号： C07D471/04 , C07D473/34 , C07D487/04
摘要： This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
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公开(公告)号：US20130231337A1
公开(公告)日：2013-09-05
申请号：US13801116
申请日：2013-03-13
发明人： Dong Zou , Wei-Sheng Huang , R. Mathew Thomas , Jan Antoinette C. Romero , Jiwei Qi , Yihan Wang , Xiaotian Zhu , William C. Shakespeare , Rajeswari Sundaramoorthi , Chester A. Metcalf, III , David C. Dalgarno , Tomi K. Sawyer
IPC分类号： C07D487/04 , C07D473/34 , C07D471/04
CPC分类号： C07D471/04 , C07D473/34 , C07D487/04
摘要： This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
摘要翻译： 本发明涉及以下通式的化合物：其中可变基团如本文所定义，及其制备和用途。
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![SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS](/abs-image/US/2019/01/31/US20190031656A1/abs.jpg.150x150.jpg)
公开(公告)号：US20190031656A1
公开(公告)日：2019-01-31
申请号：US16055362
申请日：2018-08-06
发明人： Dong Zou , Wei-Sheng Huang , R. Mathew Thomas , Jan Antoinette C. Romero , Jiwei Qi , Yihan Wang , Xiaotian Zhu , William C. Shakespeare , Rajeswari Sundaramoorthi , Chester A. Metcalf, III , David C. Dalgarno , Tomi K. Sawyer
IPC分类号： C07D471/04 , C07D473/34 , C07D487/04
摘要： This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
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![SUBSTITUTED ACETYLENIC PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS KINASE INHIBITORS](/abs-image/US/2022/03/17/US20220081440A1/abs.jpg.150x150.jpg)
公开(公告)号：US20220081440A1
公开(公告)日：2022-03-17
申请号：US17498796
申请日：2021-10-12
发明人： Dong Zou , Wei-Sheng Huang , R. Mathew Thomas , Jan Antoinette C. Romero , Jiwei Qi , Yihan Wang , Xiaotian Zhu , William C. Shakespeare , Rajeswari Sundaramoorthi , Chester A. Metcalf, III , David C. Dalgarno , Tomi K. Sawyer
IPC分类号： C07D471/04 , C07D487/04 , C07D473/34
摘要： This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
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公开(公告)号：US20170369446A1
公开(公告)日：2017-12-28
申请号：US15699579
申请日：2017-09-08
发明人： William C. Shakespeare , Wei-Sheng Huang , David C. Dalgarno , Xiaotian Zhu , R. Mathew Thomas , Yihan Wang , Jiwei Qi , Rajeswari Sundaramoorthi , Dong Zou , Chester A. Metcalf, III , Tomi K. Sawyer , Jan Antoinette C. Romero
IPC分类号： C07D231/12 , C07D417/12 , C07D403/12 , C07D233/64 , C07D277/40 , C07D233/90 , C07D417/14 , C07D403/14
CPC分类号： C07D231/12 , C07D233/64 , C07D233/90 , C07D277/40 , C07D403/12 , C07D403/14 , C07D417/12 , C07D417/14
摘要： This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
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公开(公告)号：US20170218000A1
公开(公告)日：2017-08-03
申请号：US15489593
申请日：2017-04-17
发明人： Yihan Wang , Wei-Sheng Huang , Shuangying Liu , William C. Shakespeare , R. Mathew Thomas , Jiwei Qi , Feng Li , Xiaotian Zhu , Anna Kohlmann , David C. Dalgarno , Jan Antoinette C. Romero , Dong Zou
IPC分类号： C07F9/6533 , C07F9/58 , C07F9/6521 , C07D239/48 , C07F9/6561 , C07F9/6509 , C07F9/6571 , C07F9/6512 , C07F9/6558 , C07F9/6584 , C07F9/6568
摘要： The invention features compounds of the general formula (I) in which the variable groups are as defined herein, and to their preparation and use.
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