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公开(公告)号：US11975037B2
公开(公告)日：2024-05-07
申请号：US15549954
申请日：2016-02-05
发明人： Su-Hwan Kim , Chan-Woong Park , Sun Mi Kim , Juewon Kim , Byung Gyu Kim , Wan Gi Kim , Sang Jun Lee
IPC分类号： A61K36/258 , A23L33/00 , A23L33/105 , A23L33/15 , A23L33/16 , A61K31/07 , A61K31/122 , A61K31/197 , A61K31/353 , A61K31/355 , A61K31/375 , A61K31/455 , A61K31/51 , A61K31/519 , A61K31/525 , A61K31/675 , A61K31/704 , A61K31/7048 , A61K33/00 , A61K33/06 , A61K33/26 , A61K33/30 , A61K33/42 , A61K35/32 , A61K36/232 , A61K36/40 , A61K36/534 , A61K36/54 , A61K36/64 , A61K36/725 , A61K36/79
CPC分类号： A61K36/258 , A23L33/105 , A23L33/15 , A23L33/16 , A23L33/30 , A61K31/07 , A61K31/122 , A61K31/197 , A61K31/353 , A61K31/355 , A61K31/375 , A61K31/455 , A61K31/51 , A61K31/519 , A61K31/525 , A61K31/675 , A61K31/704 , A61K31/7048 , A61K33/00 , A61K33/06 , A61K33/26 , A61K33/30 , A61K33/42 , A61K35/32 , A61K36/232 , A61K36/40 , A61K36/534 , A61K36/54 , A61K36/64 , A61K36/725 , A61K36/79 , A23V2002/00 , A61K36/258 , A61K2300/00 , A61K36/534 , A61K2300/00 , A61K36/232 , A61K2300/00 , A61K36/40 , A61K2300/00 , A61K36/54 , A61K2300/00 , A61K36/64 , A61K2300/00 , A61K36/725 , A61K2300/00 , A61K36/79 , A61K2300/00 , A23V2002/00 , A23V2200/322 , A23V2250/2124
摘要： The present specification relates to a composition for preventing, alleviating or treating burnout syndrome, containing a natural extract as an active ingredient. According to one aspect of the present invention, the composition contains a ginseng fruit extract, and thus is useful for preventing, treating and alleviating burnout syndrome. In addition, according to one aspect of the present invention, the composition further contains ginseng fruit and one or more selected from the group consisting of red ginseng, Angelica gigas, Cornus officinalis, Cervi parvum corni, and Nigella sativa, so as to maximize the synergistic effect among two or more ingredients, thereby exhibiting excellent effects on the prevention, treatment and alleviation of burnout syndrome. Therefore, there is an advantage of making individuals and society mentally and physically healthy since burnout syndrome can be prevented, treated and alleviated, by using the composition of the present invention.
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公开(公告)号：US10898535B2
公开(公告)日：2021-01-26
申请号：US16567512
申请日：2019-09-11
发明人： Byung Gyu Kim , Young-Gyu Kang , Soo Hyun Kim , Chan Woong Park , Hee Young Jeon
IPC分类号： A61K36/48 , A61Q19/00 , A61K8/9789 , A61P21/00 , A61K8/96
摘要： The present invention relates to a composition for inhibiting and preventing myopathy comprising a bean leaf extract as an active ingredient. More specifically, the composition has an effect of inhibiting the overexpression of Atrogin1 and Murf1 specifically expressed in myocyte and restoring cell activity of myocyte to inhibit and prevent muscle loss by including the extract of bean leaf at stage R6 to R8 during the growth stage of bean.
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公开(公告)号：US11096921B2
公开(公告)日：2021-08-24
申请号：US15160218
申请日：2016-05-20
发明人： Byung Gyu Kim , Hyun Woo Jeong , Su Kyung Kim , Si Young Cho , Chan Woong Park , Dae Bang Seo , Wan Gi Kim , Sang Jun Lee
IPC分类号： A61K31/34 , A61K36/258 , A23L33/11 , A23L33/105 , A23L2/52
摘要： The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
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4.发明申请公开(公告)号：US20200000867A1
公开(公告)日：2020-01-02
申请号：US16567512
申请日：2019-09-11
发明人： Byung Gyu Kim , Young-Gyu Kang , Soo Hyun Kim , Chan Woong Park , Hee Young Jeon
摘要： The present invention relates to a composition for inhibiting and preventing myopathy comprising a bean leaf extract as an active ingredient. More specifically, the composition has an effect of inhibiting the overexpression of Atrogin1 and Murf1 specifically expressed in myocyte and restoring cell activity of myocyte to inhibit and prevent muscle loss by including the extract of bean leaf at stage R6 to R8 during the growth stage of bean.
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公开(公告)号：US10279076B2
公开(公告)日：2019-05-07
申请号：US15127399
申请日：2015-03-10
发明人： Hyun Jung Shin , Jin Kyu Choi , Byung Gyu Kim , Dae Bang Seo
摘要： The present invention relates to a parenteral composition for maintaining the efficacy of a filler for a long time, containing a collagen hydrolysate as an active ingredient. The composition, according to the present invention, can maintain the efficacy of a hyaluronic acid filler for a longer time, thereby enabling the effect thereof to be maintained irrespective of a smaller frequency of filler operations, and thus there is an advantage of also reducing skin irritation. In addition, there is an advantage of enabling an immediate effect since an administration method is simple as a parenteral administration and enables direct penetration into the skin.
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公开(公告)号：US10022351B2
公开(公告)日：2018-07-17
申请号：US15160239
申请日：2016-05-20
发明人： Byung Gyu Kim , Hyun Woo Jeong , Su Kyung Kim , Si Young Cho , Chan Woong Park , Dae Bang Seo , Wan Gi Kim , Sang Jun Lee
IPC分类号： A61K31/34 , A23L2/52 , A61K36/258 , A23L33/11 , A23L33/105
摘要： The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
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公开(公告)号：US09999611B2
公开(公告)日：2018-06-19
申请号：US15160197
申请日：2016-05-20
发明人： Byung Gyu Kim , Hyun Woo Jeong , Su Kyung Kim , Si Young Cho , Chan Woong Park , Dae Bang Seo , Wan Gi Kim , Sang Jun Lee
IPC分类号： A61K31/34 , A23L2/52 , A61K36/258 , A23L33/11 , A23L33/105
CPC分类号： A61K31/34 , A23L2/52 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/258
摘要： The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
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公开(公告)号：US09913823B2
公开(公告)日：2018-03-13
申请号：US14352444
申请日：2012-10-18
发明人： Byung Gyu Kim , Hyun Woo Jeong , Su Kyung Kim , Si Young Cho , Chan Woong Park , Dae Bang Seo , Wan Gi Kim , Sang Jun Lee
IPC分类号： A61K31/34 , A23L1/30 , A61K36/258 , A23L33/11 , A23L2/52 , A23L33/105
CPC分类号： A61K31/34 , A23L2/52 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/258
摘要： The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
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公开(公告)号：US09474706B2
公开(公告)日：2016-10-25
申请号：US14771372
申请日：2014-02-27
发明人： Hyun Jung Shin , Jin Kyu Choi , Byung Gyu Kim , Dae Bang Seo , Sang Jun Lee
CPC分类号： A61K8/65 , A23L33/18 , A23V2002/00 , A61K8/735 , A61K9/0095 , A61K9/2059 , A61K9/4875 , A61K31/728 , A61K36/258 , A61K38/005 , A61K38/06 , A61K38/39 , A61K2800/91 , A61Q19/00 , A61Q19/08 , A61K2300/00
摘要： The present invention relates to a composition for maintaining efficacy of a filler for a long period of time by containing collagen as an active ingredient. The composition according to the present invention is useful since the composition can promote the synthesis of hyaluronic acid and inhibit activity of hyaluronidase, thereby maintaining the efficacy of a hyaluronic acid filler for a longer period of time. Therefore, even with less number of times of filler injection, the efficacy of the filler can be maintained and skin irritation can be also reduced.
摘要翻译： 本发明涉及通过含有胶原作为有效成分来长期维持填充剂的功效的组合物。 根据本发明的组合物是有用的，因为组合物可以促进透明质酸的合成并抑制透明质酸酶的活性，从而保持透明质酸填充剂的更长时间的功效。 因此，即使填充剂注射次数较少，也可以保持填充剂的功效，并且还可以减少皮肤刺激。
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公开(公告)号：US20140371307A1
公开(公告)日：2014-12-18
申请号：US14352444
申请日：2012-10-18
发明人： Byung Gyu Kim , Hyun Woo Jeong , Su Kyung Kim , Si Young Cho , Chan Woong Park , Dae Bang Seo , Wan Gi Kim , Sang Jun Lee
IPC分类号： A61K31/34 , A23L1/30 , A61K36/258
CPC分类号： A61K31/34 , A23L2/52 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/258
摘要： The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases.
摘要翻译： 本发明涉及式1化合物和SIRT 1活化剂，其包括其衍生物或其药学上可接受的盐作为活性成分。 本发明还涉及包含用于解毒的SIRT1激活剂，用于改善代谢紊乱，用于预防或改善眼部疾病或预防或改善免疫疾病的组合物。
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