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公开(公告)号：US20230287335A1
公开(公告)日：2023-09-14
申请号：US18018389
申请日：2021-07-27
Applicant: AMGEN INC.
Inventor： Nicholas MARCHAND , Glen BOLTON , Sara Ann GALL , Jian WU
CPC classification number: C12N5/0018 , B01D61/027 , B01D65/08 , C12N2501/105 , C12N2501/33 , B01D2321/168
Abstract: Presented herein are methods for preparing and treating mammalian cell culture media through the addition of low levels of poloxamer and nanofiltration. Low levels of poloxamer improved flux and retained greater levels of a growth factor.
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