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    Optimizing medication dosage based on analyte sensor data
    1.
    发明授权
    Optimizing medication dosage based on analyte sensor data 有权

    公开(公告)号：US11737687B2

    公开(公告)日：2023-08-29

    申请号：US16252980

    申请日：2019-01-21

    申请人： Abbott Diabetes Care Inc.

    发明人： Mark K. Sloan ,  Martin J. Fennell ,  Daniel M. Bernstein

    IPC分类号： A61B5/145 ,  A61M5/172 ,  A61B5/00 ,  G16H20/17 ,  G16H20/10 ,  A61M5/142

    CPC分类号： A61B5/14532 ,  A61B5/4839 ,  A61M5/1723 ,  G16H20/10 ,  G16H20/17 ,  A61M2005/14208

    摘要： Methods, apparatuses, and systems are provided for determining whether to administer a medication dose as a single dose or whether to fractionate the single dose to be administered as at least two discrete doses. Embodiments include determining a first analyte level and a first rate of change of the analyte level; determining an initial medication dose based on one or more anticipated subsequent medication doses, the first analyte level relative to an analyte level threshold, and the first rate of change of the analyte level relative to a rate of change threshold; administering the initial medication dose; determining a second analyte level and a second rate of change of the analyte level based on subsequent analyte data; and determining a subsequent medication dose based on the second analyte level relative to the analyte level threshold and the second rate of change relative to the rate of change threshold.

    METHODS, DEVICES, AND SYSTEMS RELATED TO ANALYTE MONITORING
    6.
    发明申请
    METHODS, DEVICES, AND SYSTEMS RELATED TO ANALYTE MONITORING 有权

    公开(公告)号：US20210169379A1

    公开(公告)日：2021-06-10

    申请号：US17073589

    申请日：2020-10-19

    申请人： ABBOTT DIABETES CARE INC.

    发明人： Mark K. Sloan ,  Royce Cheng ,  Gary A. Hayter ,  Marc B. Taub ,  Mani Gopal

    IPC分类号： A61B5/145 ,  G16H10/40 ,  A61B5/00 ,  G16H40/63 ,  A61B5/1495

    摘要： Generally, methods, devices, and systems related to analyte monitoring and data logging are provided—e.g., as related to in vivo analyte monitoring devices and systems. In some aspects, methods, devices, and systems are provided that relate to enable related settings based on an expected use of an in vivo positioned sensor; logging or otherwise recording analyte levels acquired or derived—e.g., sample analyte levels more frequently than they are logged or otherwise recorded in memory; dynamically adjust the data logging frequency; randomly determine times of acquiring or storing analyte levels from the in-vivo positioned analyte sensors; and enable recording related settings when the system is operable.

    METHODS, DEVICES, AND SYSTEMS RELATED TO ANALYTE MONITORING
    7.
    发明申请
    METHODS, DEVICES, AND SYSTEMS RELATED TO ANALYTE MONITORING 有权

    公开(公告)号：US20210068715A1

    公开(公告)日：2021-03-11

    申请号：US16950517

    申请日：2020-11-17

    申请人： ABBOTT DIABETES CARE INC.

    发明人： Mark K. Sloan ,  Royce Cheng ,  Gary A. Hayter ,  Marc B. Taub ,  Mani Gopal

    IPC分类号： A61B5/145 ,  G16H40/63 ,  G16H10/40 ,  A61B5/00

    摘要： Generally, methods, devices, and systems related to analyte monitoring and data logging are provided—e.g., as related to in vivo analyte monitoring devices and systems. In some aspects, methods, devices, and systems are provided that relate to enable related settings based on an expected use of an in vivo positioned sensor; logging or otherwise recording analyte levels acquired or derived—e.g., sample analyte levels more frequently than they are logged or otherwise recorded in memory; dynamically adjust the data logging frequency; randomly determine times of acquiring or storing analyte levels from the in-vivo positioned analyte sensors; and enable recording related settings when the system is operable.

    ANALYTE SENSORS EMPLOYING MULTIPLE ENZYMES AND METHODS ASSOCIATED THEREWITH
    8.
    发明申请
    ANALYTE SENSORS EMPLOYING MULTIPLE ENZYMES AND METHODS ASSOCIATED THEREWITH 审中-公开

    公开(公告)号：US20200237276A1

    公开(公告)日：2020-07-30

    申请号：US16774841

    申请日：2020-01-28

    申请人： Abbott Diabetes Care Inc.

    发明人： Stephen Oja ,  Tianmei Ouyang ,  Hyun Cho ,  Lam N. Tran ,  Benjamin J. Feldman ,  Mark K. Sloan ,  Ashwin Kumar ,  Namvar Kiaie ,  Michael R. Love

    IPC分类号： A61B5/1486 ,  A61B5/145

    摘要： Multiple enzymes may be present in the active area(s) of an electrochemical sensor to facilitate analysis of one or more analytes. The multiple enzymes may function independently to detect several analytes or in concert to detect a single analyte. One sensor configuration includes a first active area and a second active area, where the first active area has an oxidation-reduction potential that is sufficiently separated from the oxidation-reduction potential of the second active area to allow independent signal production. Some sensor configurations may have an active area overcoated with a multi-component membrane containing two or more different membrane polymers. Sensor configurations having multiple enzymes capable of interacting in concert include those in which a first enzyme converts an analyte into a first product and a second enzyme converts the first product into a second product, thereby generating a signal at a working electrode that is proportional to the analyte concentration.

    ANALYTE SENSORS AND SENSING METHODS FEATURING DUAL DETECTION OF GLUCOSE AND KETONES
    9.
    发明申请
    ANALYTE SENSORS AND SENSING METHODS FEATURING DUAL DETECTION OF GLUCOSE AND KETONES 审中-公开

    公开(公告)号：US20200237275A1

    公开(公告)日：2020-07-30

    申请号：US16774835

    申请日：2020-01-28

    申请人： Abbott Diabetes Care Inc.

    发明人： Benjamin J. Feldman ,  Mark K. Sloan ,  Ashwin Kumar ,  Namvar Kiaie ,  Michael R. Love

    IPC分类号： A61B5/1486 ,  A61B5/145 ,  A61L31/04

    摘要： Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.