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公开(公告)号:US11692218B2
公开(公告)日:2023-07-04
申请号:US17552135
申请日:2021-12-15
Applicant: 10x Genomics, Inc.
Inventor: Camilla Engblom , Kim Thrane , Jeffrey Mold , Jonas Frisen , Joakim Lundeberg , Qirong Lin
IPC: C12Q1/6837 , C12Q1/6881 , C12Q1/6869
CPC classification number: C12Q1/6837 , C12Q1/6869 , C12Q1/6881 , C12Q1/6806 , C12Q2525/179 , C12Q2563/179 , C12Q2565/514 , C12Q2565/518 , C12Q2565/537
Abstract: Provided herein are methods, compositions, and kits for the detection of immune cell clonotypes and immune cell analytes within a biological sample.
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公开(公告)号:US12180543B2
公开(公告)日:2024-12-31
申请号:US17312375
申请日:2019-12-06
Applicant: 10x Genomics, Inc.
Inventor: Cedric Uytingco , Zachary Bent , Eswar Prasad Ramachandran Iyer , Fernandino Valdecanas , Meghan L. F. Frey , Steven William Short , Yifeng Yin , Rajiv Bharadwaj , Joakim Lundeberg , Augusto Manuel Tentori , David Maurice Cox , Jennifer Chew , Felice Alessio Bava , Linda Kvastad , Andrew D. Price
IPC: C12Q1/6844 , B01L3/00 , B01L9/00 , C12N15/10 , C12Q1/6837 , C12Q1/6841 , C12Q1/6855 , C12Q1/6869 , C12Q1/6874 , C12Q1/6876 , C12Q1/6881 , G01N21/64 , G01N33/483 , G01N35/00 , G02B21/16 , G02B21/26 , G02B21/34 , G02B21/36
Abstract: A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.
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公开(公告)号:US20240080346A1
公开(公告)日:2024-03-07
申请号:US18497415
申请日:2023-10-30
Applicant: 10x Genomics, Inc.
Inventor: Camilla Engblom , Kim Thrane , Jeffrey Mold , Jonas Frisen , Joakim Lundeberg , Qirong Lin
IPC: H04L9/40
CPC classification number: H04L63/104 , H04L63/102 , H04L63/30
Abstract: Provided herein are methods, compositions, and kits for the detection of immune cell clonotypes and immune cell analytes within a biological sample.
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公开(公告)号:US11845979B2
公开(公告)日:2023-12-19
申请号:US18315289
申请日:2023-05-10
Applicant: 10x Genomics, Inc.
Inventor: Camilla Engblom , Kim Thrane , Jeffrey Mold , Jonas Frisen , Joakim Lundeberg , Qirong Lin
IPC: C12Q1/6837 , C12Q1/6881 , C12Q1/6869
CPC classification number: C12Q1/6837 , C12Q1/6869 , C12Q1/6881
Abstract: Provided herein are methods, compositions, and kits for the detection of immune cell clonotypes and immune cell analytes within a biological sample.
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公开(公告)号:US20230279477A1
公开(公告)日:2023-09-07
申请号:US18302443
申请日:2023-04-18
Applicant: 10x Genomics, Inc.
Inventor: Linda Kvastad , Mohammadreza Mirzazadeh , Ludvig Ale Larsson , Joakim Lundeberg
IPC: C12Q1/6841 , C12Q1/6876 , C12Q1/686
CPC classification number: C12Q1/6841 , C12Q1/6876 , C12Q1/686 , C12Q2600/178
Abstract: Provided herein are methods for spatial analysis that captures non-poly(A)-containing RNA molecules, such as long non-coding RNAs and microRNAs. Methods, kits, and compositions for spatial analysis using targeted RNA capture using randomer capture probes are disclosed herein.
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公开(公告)号:US20210324457A1
公开(公告)日:2021-10-21
申请号:US17271866
申请日:2019-08-27
Applicant: Eswar Prasad RAMACHANDRAN IYER , Michael SCHNALL-LEVIN , Augusto Manuel TENTORI , Tarje Sigurd MIKKELSEN , Benjamin HINDSON , Michael Ybarra LUCERO , Rajiv BHARADWAJ , Yifeng YIN , Zachary BENT , Jennifer CHEW , Meghan L. F. FREY , Linda KVASTAD , Joakim LUNDEBERG , Eva Gracia VILLACAMPA , 10x Genomics, Inc.
Inventor: Eswar Prasad Ramachandran Iyer , Michael Schnall-Levin , Augusto Manuel Tentori , Tarjei Sigurd Mikkelsen , Benjamin Hindson , Michael Ybarra Lucero , Rajiv Bharadwaj , Yifeng Yin , Zachary Bent , Jennifer Chew , Meghan L. F. Frey , Linda Kvastad , Joakim Lundeberg , Eva Gracia Villacampa
IPC: C12Q1/6837 , C12Q1/6841
Abstract: This disclosure relates to methods for generating spatially barcoded arrays using concentration gradients.
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公开(公告)号:US20240392353A1
公开(公告)日:2024-11-28
申请号:US18800754
申请日:2024-08-12
Applicant: 10x Genomics, Inc.
Inventor: Camilla Engblom , Kim Thrane , Jeffrey Mold , Jonas Frisen , Joakim Lundeberg , Qirong Lin
IPC: C12Q1/6837 , C12Q1/6869 , C12Q1/6881 , H04L9/40
Abstract: Provided herein are methods, compositions, and kits for the detection of immune cell clonotypes and immune cell analytes within a biological sample.
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公开(公告)号:US20230340577A1
公开(公告)日:2023-10-26
申请号:US18315289
申请日:2023-05-10
Applicant: 10x Genomics, Inc.
Inventor: Camilla Engblom , Kim Thrane , Jeffrey Mold , Jonas Frisen , Joakim Lundeberg , Qirong Lin
IPC: C12Q1/6837 , C12Q1/6881 , C12Q1/6869
CPC classification number: C12Q1/6837 , C12Q1/6881 , C12Q1/6869
Abstract: Provided herein are methods, compositions, and kits for the detection of immune cell clonotypes and immune cell analytes within a biological sample.
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公开(公告)号:US12098417B2
公开(公告)日:2024-09-24
申请号:US18497415
申请日:2023-10-30
Applicant: 10x Genomics, Inc.
Inventor: Camilla Engblom , Kim Thrane , Jeffrey Mold , Jonas Frisen , Joakim Lundeberg , Qirong Lin
IPC: C12Q1/6837 , C12Q1/6869 , C12Q1/6881 , H04L9/40
CPC classification number: C12Q1/6837 , C12Q1/6869 , C12Q1/6881 , H04L63/30 , C12Q1/6806 , C12Q2525/179 , C12Q2563/179 , C12Q2565/514 , C12Q2565/518 , C12Q2565/537
Abstract: Provided herein are methods, compositions, and kits for the detection of immune cell clonotypes and immune cell analytes within a biological sample.
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公开(公告)号:US20240068017A1
公开(公告)日:2024-02-29
申请号:US18269593
申请日:2021-12-28
Applicant: 10x Genomics, Inc.
Inventor: Joakim Lundeberg , Eva Gracia Villacampa
IPC: C12Q1/6837 , G01N1/30 , G01N21/64
CPC classification number: C12Q1/6837 , G01N1/30 , G01N21/6458 , G01N2001/302
Abstract: Provided herein are methods and kits for determining the optimal conditions for analyte capture in biological samples.
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