公开(公告)号：US09090668B2

公开(公告)日：2015-07-28

申请号：US12593221

申请日：2008-03-26

Applicant: Hiroaki Suga ,  Hiroshi Murakami ,  Yuki Goto ,  Yusuke Yamagishi ,  Hiroshi Ashigai ,  Yusuke Sako

Inventor： Hiroaki Suga ,  Hiroshi Murakami ,  Yuki Goto ,  Yusuke Yamagishi ,  Hiroshi Ashigai ,  Yusuke Sako

IPC: C07K7/56 ,  C07K7/06 ,  C07K7/08 ,  C12N15/67 ,  C12P21/02

CPC classification number: C07K7/56 ,  C07K7/06 ,  C07K7/08 ,  C12N15/67 ,  C12P21/02

Abstract: The objective is to provide a novel process for synthesizing a cyclic peptide compound. It is also an objective to provide a novel cyclic peptide compound. The novel process for synthesizing a cyclic peptide compound comprises the steps of: (1) translationally synthesizing a non-cyclic peptide compound having in a molecule a functional group 1 and a functional group 2, which are a pair of functional groups capable of reacting to form a bond, and (2) cyclizing the non-cyclic peptide compound by the reaction of the functional groups 1 and 2 to form a bond. The novel cyclic peptide compound can be synthesized by the process.

Abstract translation: 目的是提供一种合成环肽化合物的新方法。 提供新的环肽化合物也是目的。 用于合成环肽化合物的新方法包括以下步骤：（1）在分子中转化合成具有官能团1和官能团2的非环状肽化合物，所述官能团是能够使 形成键，和（2）通过官能团1和2的反应使非环肽化合物环化以形成键。 可以通过该方法合成新的环肽化合物。

公开(公告)号：US20100168380A1

公开(公告)日：2010-07-01

申请号：US12593221

申请日：2008-03-26

Applicant: Hiroaki Suga ,  Hiroshi Murakami ,  Yuki Goto ,  Yusuke Yamagishi ,  Hiroshi Ashigai ,  Yusuke Sako

Inventor： Hiroaki Suga ,  Hiroshi Murakami ,  Yuki Goto ,  Yusuke Yamagishi ,  Hiroshi Ashigai ,  Yusuke Sako

IPC: C07K1/00 ,  C12P21/00

CPC classification number: C07K7/56 ,  C07K7/06 ,  C07K7/08 ,  C12N15/67 ,  C12P21/02

Abstract: The objective is to provide a novel process for synthesizing a cyclic peptide compound. It is also an objective to provide a novel cyclic peptide compound. The novel process for synthesizing a cyclic peptide compound comprises the steps of: (1) translationally synthesizing a non-cyclic peptide compound having in a molecule a functional group 1 and a functional group 2, which are a pair of functional groups capable of reacting to form a bond, and (2) cyclizing the non-cyclic peptide compound by the reaction of the functional groups 1 and 2 to form a bond. The novel cyclic peptide compound can be synthesized by the process.

Abstract translation: 目的是提供一种合成环肽化合物的新方法。 提供新的环肽化合物也是目的。 用于合成环肽化合物的新方法包括以下步骤：（1）在分子中转化合成具有官能团1和官能团2的能够对 形成键，和（2）通过官能团1和2的反应使非环肽化合物环化以形成键。 可以通过该方法合成新的环肽化合物。