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1.
公开(公告)号:US20100310572A1
公开(公告)日:2010-12-09
申请号:US12798748
申请日:2010-04-08
申请人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
发明人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
IPC分类号: A61K39/395 , A61P31/14
CPC分类号: C07K16/10 , A61K2039/505 , A61K2039/507 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/622 , C07K2317/76 , C12N2760/20122 , G01N33/56983
摘要: Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. In certain embodiments, they can be used in the post-exposure prophylaxis of rabies.
摘要翻译: 提供特异性结合狂犬病病毒并能够中和病毒的结合分子。 还提供了编码结合分子的核酸分子,包含结合分子的组合物以及鉴定或产生结合分子的方法。 结合分子可用于诊断,预防和/或治疗由狂犬病病毒引起的病症。 在某些实施方案中,它们可以用于狂犬病的暴露后预防。
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2.
公开(公告)号:US20100272724A1
公开(公告)日:2010-10-28
申请号:US12459661
申请日:2009-07-06
申请人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
发明人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
IPC分类号: A61K39/395 , C07H21/04 , C07K16/00 , A61P31/14 , C12N15/63 , C12N5/10 , C12P21/00 , C12Q1/70
CPC分类号: C07K16/10 , A61K2039/505 , A61K2039/507 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/622 , C07K2317/76 , C12N2760/20122 , G01N33/56983
摘要: The invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the post-exposure prophylaxis of rabies.
摘要翻译: 本发明提供了特异性结合狂犬病毒并能够中和病毒的结合分子。 本发明还提供了编码结合分子的核酸分子,包含结合分子的组合物以及鉴定或产生结合分子的方法。 结合分子可用于诊断,预防和/或治疗由狂犬病病毒引起的病症。 优选地,它们可用于狂犬病的暴露后预防。
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3.
公开(公告)号:US09005624B2
公开(公告)日:2015-04-14
申请号:US12798748
申请日:2010-04-08
申请人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
发明人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
IPC分类号: A61K39/395 , A61P31/14 , C07K16/10 , C07K14/005 , G01N33/569 , A61K39/00
CPC分类号: C07K16/10 , A61K2039/505 , A61K2039/507 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/622 , C07K2317/76 , C12N2760/20122 , G01N33/56983
摘要: Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. In certain embodiments, they can be used in the post-exposure prophylaxis of rabies.
摘要翻译: 提供特异性结合狂犬病病毒并能够中和病毒的结合分子。 还提供了编码结合分子的核酸分子,包含结合分子的组合物以及鉴定或产生结合分子的方法。 结合分子可用于诊断,预防和/或治疗由狂犬病病毒引起的病症。 在某些实施方案中,它们可以用于狂犬病的暴露后预防。
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4.
公开(公告)号:US20080226652A1
公开(公告)日:2008-09-18
申请号:US11978742
申请日:2007-10-29
申请人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
发明人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
IPC分类号: A61K39/395 , A61P43/00
CPC分类号: C07K16/10 , A61K2039/505 , A61K2039/507 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/622 , C07K2317/76 , C12N2760/20122 , G01N33/56983
摘要: Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. In certain embodiments, they can be used in the post-exposure prophylaxis of rabies.
摘要翻译: 提供特异性结合狂犬病病毒并能够中和病毒的结合分子。 还提供了编码结合分子的核酸分子,包含结合分子的组合物以及鉴定或产生结合分子的方法。 结合分子可用于诊断,预防和/或治疗由狂犬病病毒引起的病症。 在某些实施方案中,它们可以用于狂犬病的暴露后预防。
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5.
公开(公告)号:US08148497B2
公开(公告)日:2012-04-03
申请号:US12459661
申请日:2009-07-06
申请人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan de Kruif
发明人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan de Kruif
CPC分类号: C07K16/10 , A61K2039/505 , A61K2039/507 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/622 , C07K2317/76 , C12N2760/20122 , G01N33/56983
摘要: The invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the post-exposure prophylaxis of rabies.
摘要翻译: 本发明提供了特异性结合狂犬病毒并能够中和病毒的结合分子。 本发明还提供了编码结合分子的核酸分子,包含结合分子的组合物以及鉴定或产生结合分子的方法。 结合分子可用于诊断,预防和/或治疗由狂犬病病毒引起的病症。 优选地,它们可用于狂犬病的暴露后预防。
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公开(公告)号:US07740852B2
公开(公告)日:2010-06-22
申请号:US11978742
申请日:2007-10-29
申请人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
发明人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
IPC分类号: A61K39/42
CPC分类号: C07K16/10 , A61K2039/505 , A61K2039/507 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/622 , C07K2317/76 , C12N2760/20122 , G01N33/56983
摘要: Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. In certain embodiments, they can be used in the post-exposure prophylaxis of rabies.
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