公开(公告)号：US09545340B1

公开(公告)日：2017-01-17

申请号：US12207137

申请日：2008-09-09

申请人： Wayne H. Knox ,  Krystel R. Huxlin ,  Li Ding

发明人： Wayne H. Knox ,  Krystel R. Huxlin ,  Li Ding

IPC分类号： A61F9/008

CPC分类号： A61F9/00827 ,  A61F9/008 ,  A61F9/00804 ,  A61F9/00829 ,  A61F2009/00842 ,  A61F2009/00846 ,  A61F2009/00848 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088

摘要： By adapting femtosecond micromachining approaches developed in hydrogels, we can perform Intra-tissue Refractive Index Shaping (IRIS) in biological tissues. We reduced femtosecond laser pulse energies below the optical breakdown thresholds to create grating patterns that are associated with a change in the refractive index of the tissue. To increase two-photon absorption, we used a two (or more)-photon-absorbing chromophore.

摘要翻译： 通过适应在水凝胶中开发的飞秒微加工方法，我们可以在生物组织中进行组织内折射指数整形（IRIS）。 我们将飞秒激光脉冲能量降低到光学击穿阈值以下，以产生与组织的折射率变化相关联的光栅图案。 为了增加双光子吸收，我们使用了两个（或更多）光子吸收发色团。

公开(公告)号：US20120310223A1

公开(公告)日：2012-12-06

申请号：US13326403

申请日：2011-12-15

申请人： Wayne H. Knox ,  Krystel R. Huxlin

发明人： Wayne H. Knox ,  Krystel R. Huxlin

IPC分类号： A61F9/01

CPC分类号： A61F9/00827 ,  A61F9/00834 ,  A61F2009/00842 ,  A61F2009/00846 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088

摘要： A method for modifying a refractive property of ocular tissue in an eye by creating at least one optically-modified gradient index (GRIN) layer in the corneal stroma and/or the crystalline by continuously scanning a continuous stream of laser pulses having a focal volume from a laser having a known average power along a continuous line having a smoothly changing refractive index within the tissue, and varying either or both of the scan speed and the laser average power during the scan. The method may further involve determining a desired vision correction adjustment, and determining a position, number, and design parameters of gradient index (GRIN) layers to be created within the ocular tissue to provide the desired vision correction.

摘要翻译： 一种通过在角膜基质和/或晶体中产生至少一个光学修饰的梯度指数（GRIN）层来连续地扫描具有聚焦体积的激光脉冲的流量来修改眼睛中眼组织的折射特性的方法， 具有在组织内具有平滑变化的折射率的连续线具有已知平均功率的激光，并且在扫描期间改变扫描速度和激光平均功率中的任一者或两者。 该方法还可以包括确定期望的视力矫正调整，以及确定要在眼组织内产生的梯度指数（GRIN）层的位置，数量和设计参数，以提供期望的视力矫正。

公开(公告)号：US20110071509A1

公开(公告)日：2011-03-24

申请号：US12895978

申请日：2010-10-01

申请人： Wayne H. Knox ,  Krystel R. Huxlin

发明人： Wayne H. Knox ,  Krystel R. Huxlin

IPC分类号： A61F9/01

CPC分类号： A61F9/00829 ,  A61F9/008 ,  A61F9/00827 ,  A61F2009/00842 ,  A61F2009/00851 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/00897

摘要： A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss.

摘要翻译： 一种用于向患者提供视力矫正的方法。 该方法包括：（a）测量患者所需的视力矫正度，并确定需要定位在角膜内的折射结构的位置和形状，以部分校正患者的视力; （b）以足够高的强度将飞秒激光脉冲引导和聚焦在角膜内的蓝色光谱区域，以改变焦点区域内的角膜的折射率，但不足以破坏角膜或影响角膜外部的角膜组织 焦点区域; 和（c）扫描角膜或透镜体积上的激光脉冲，以在角膜或透镜中提供焦点区域的折射结构。 此外，折射结构的特征在于折射率的变化，并且表现出很少或没有散射损失。

公开(公告)号：US20090005764A1

公开(公告)日：2009-01-01

申请号：US12146976

申请日：2008-06-26

申请人： Wayne H. Knox ,  Li Ding ,  Krystel R. Huxlin ,  Jay F. Kunzler

发明人： Wayne H. Knox ,  Li Ding ,  Krystel R. Huxlin ,  Jay F. Kunzler

IPC分类号： A61B18/20

CPC分类号： A61F9/00804 ,  A61F9/008 ,  A61F9/00829 ,  A61F2009/00842 ,  A61F2009/00848 ,  A61F2009/0087 ,  A61F2009/00872 ,  A61F2009/0088

摘要： A method for modifying the refractive index of ocular tissues. The method comprises irradiating select regions of ocular tissue with a visible or near-IR laser. The irradiation results in the formation of structures in the ocular tissue, characterized by a change in refractive index, and which exhibit little or no scattering loss.

摘要翻译： 一种改变眼组织折射率的方法。 该方法包括用可见光或近红外激光照射眼组织的选择区域。 照射导致眼组织中的结构的形成，其特征在于折射率的变化，并且表现出很少或没有散射损失。

公开(公告)号：US07460785B2

公开(公告)日：2008-12-02

申请号：US10109623

申请日：2002-03-28

申请人： Mihaela Dinu ,  Hernando Garcia ,  Daniel Kilper ,  Wayne H. Knox ,  Howard R. Stuart ,  Chunhui Xu

发明人： Mihaela Dinu ,  Hernando Garcia ,  Daniel Kilper ,  Wayne H. Knox ,  Howard R. Stuart ,  Chunhui Xu

IPC分类号： H04B17/00

CPC分类号： H04B10/0795 ,  H04B10/27 ,  H04J14/02

摘要： An optical performance monitor (OPM), e.g., for use in an optical network. The OPM may be configured to characterize one or more impairments in an optical signal modulated with data. The OPM has an optical autocorrelator configured to sample the autocorrelation function of the optical signal, e.g., using two-photon absorption. Autocorrelation points at various bit delays independently or in combination with average optical power may be used to detect and/or quantify one or more of the following: loss of data modulation, signal contrast, pulse broadening, peak power fluctuations, timing jitter, and deviations from the pseudo-random character of data. In addition, the OPM may be configured to perform Fourier transformation based on the autocorrelation points to obtain corresponding spectral components. The spectral components may be used to detect and/or quantify one or more of chromatic dispersion, polarization mode dispersion, and misalignment of a pulse carver and data modulator. The OPM may be further configured to generate feedback, e.g., to network operators to improve network performance.

摘要翻译： 光学性能监视器（OPM），例如用于光网络。 OPM可以被配置为表征用数据调制的光信号中的一个或多个损伤。 OPM具有配置成对光信号的自相关函数进行采样的光自相关器，例如使用双光子吸收。 独立地或与平均光功率组合的各种位延迟的自相关点可用于检测和/或量化以下中的一个或多个：数据调制丢失，信号对比度，脉冲展宽，峰值功率波动，定时抖动和偏差 从数据的伪随机字符。 此外，OPM可以被配置为基于自相关点执行傅里叶变换，以获得相应的光谱分量。 频谱分量可用于检测和/或量化脉冲编码器和数据调制器的色散，偏振模色散和未对准中的一个或多个。 OPM可以被进一步配置为产生反馈，例如，向网络运营商产生改善网络性能的反馈。

公开(公告)号：US5726787A

公开(公告)日：1998-03-10

申请号：US579864

申请日：1995-12-28

申请人： Hermann A. Haus ,  Wayne H. Knox ,  David A. B. Miller

发明人： Hermann A. Haus ,  Wayne H. Knox ,  David A. B. Miller

IPC分类号： H04J14/00 ,  H04B10/02 ,  H04B10/04 ,  H04B10/06 ,  H04B10/14 ,  H04B10/18 ,  H04B10/26 ,  H04B10/28 ,  H04J14/02 ,  H04B10/00

CPC分类号： H04B10/25077 ,  H04B2210/258

摘要： For use in a soliton optical pulse transmission system, an apparatus for, and method of, increasing a signal-to-noise ratio of the system. The apparatus includes: (1) a component for receiving a soliton and an accompanying background noise from the system and increasing a power density of the soliton and the accompanying background noise and (2) a saturable absorber, having a predetermined recombination rate, for receiving and absorbing a portion of the soliton and the accompanying background noise, the predetermined recombination rate causing the saturable absorber to absorb a lesser portion of the soliton than of the accompanying background noise, the component having increased the power density of the soliton and the accompanying background noise to increase a sensitivity of the saturable absorber, the apparatus thereby increasing the signal-to-noise ratio of the system.

摘要翻译： 用于孤子光脉冲传输系统，用于增加系统的信噪比的装置和方法。 该装置包括：（1）用于从系统接收孤子和伴随的背景噪声的组件，并增加孤子的功率密度和伴随的背景噪声;以及（2）具有预定重组速率的可饱和吸收器，用于接收 并且吸收孤子的一部分和伴随的背景噪声，预定的复合速率导致可饱和吸收体吸收孤子的较小部分而不是伴随的背景噪声，该成分增加了孤子的功率密度和伴随的背景 噪声以提高可饱和吸收器的灵敏度，从而提高了系统的信噪比。

公开(公告)号：US5526155A

公开(公告)日：1996-06-11

申请号：US151441

申请日：1993-11-12

申请人： Wayne H. Knox ,  David A. B. Miller ,  Martin C. Nuss

发明人： Wayne H. Knox ,  David A. B. Miller ,  Martin C. Nuss

IPC分类号： H04J14/00 ,  G02B6/34 ,  G02B6/42 ,  H04J14/02

CPC分类号： G02B6/2931 ,  G02B6/29313 ,  G02B6/2938 ,  G02B6/29394 ,  G02B6/29395 ,  G02B6/4246 ,  H04J14/02

摘要： The present invention provides an apparatus and method for high-density optical wavelength division multiplexing (WDM) using a single optical source. An optical wavelength division multiplexer in accordance with the present invention includes an optical source providing an optical pulse signal. A wavelength splitter separates the optical pulse signal spectrum into a plurality of channel signals at different wavelengths such that each channel signal may be separately modulated or otherwise processed. A wavelength combiner then recombines the separately modulated channel signals to provide a high-density WDM optical signal particularly well-suited for use in optical circuit interconnection and optical communication network applications. The high-density single-source multiplexer of the present invention may also be conveniently adjusted to align channel signal wavelengths or to compensate for optical fiber dispersion.

摘要翻译： 本发明提供使用单个光源的高密度光波分复用（WDM）的装置和方法。 根据本发明的光波分复用器包括提供光脉冲信号的光源。 波长分离器将光脉冲信号频谱分离成不同波长的多个信道信号，使得每个信道信号可以被单独调制或以其他方式处理。 然后，波长组合器将单独调制的信道信号复合以提供特别适用于光电互连和光通信网络应用的高密度WDM光信号。 本发明的高密度单源多路复用器也可以方便地调整以对齐信道信号波长或补偿光纤色散。

公开(公告)号：US5007059A

公开(公告)日：1991-04-09

申请号：US523622

申请日：1990-05-15

申请人： Ursula Keller ,  Wayne H. Knox

发明人： Ursula Keller ,  Wayne H. Knox

IPC分类号： H01S3/098 ,  H01S3/108 ,  H01S5/065 ,  H01S5/14

CPC分类号： H01S3/1112 ,  H01S3/08027 ,  H01S3/082 ,  H01S3/105 ,  H01S3/1115

摘要： Modelocking of a solid state laser such as a Ti:Al.sub.2 O.sub.3 laser is achieved by employing an external cavity defined by spatially separated reflective elements wherein at least one of the reflective elements exhibits a nonlinear characteristic in response to an impinging light beam. Exemplary nonlinear reflective elements are described using bulk semiconductor material or semiconductor quantum well structures integrated with a rear reflector such as a stack of quarter-wave thick dielectric or semiconductor material. Tuning control of the nonlinear reflective element may be introduced with temperature control arrangements and with mechanical translation arrangements in conjunction with lateral band gap engineering of the semiconductor material.

公开(公告)号：US20180373060A1

公开(公告)日：2018-12-27

申请号：US16062241

申请日：2016-12-14

申请人： Wayne H. Knox ,  Gustavo A. Gandara-Montano ,  Leonard Zheleznyak

发明人： Wayne H. Knox ,  Gustavo A. Gandara-Montano ,  Leonard Zheleznyak

IPC分类号： G02C7/04 ,  A61F2/16 ,  A61F9/008

摘要： Described refractive correctors, include, but are not limited to, intraocular lenses (IOLs), contact lenses, corneal inlays, and other optical components or devices, incorporating a continuous central phase zone and peripheral phase discontinuities. Further embodiments are directed to a method for using a laser to modify the refractive properties of refractive correctors to form such continuous central phase zone and peripheral phase discontinuities, and other applications. The refractive corrector and methods adapt a Fresnel lens structure to include continuous phase retarding regions having a wavefront height of greater than one design wavelength in a central zone of a refractive corrector to improve human vision applications, while maintaining benefits of phase wrapping in the peripheral region.

公开(公告)号：US20180173009A1

公开(公告)日：2018-06-21

申请号：US15577060

申请日：2016-05-26

申请人： Wayne H. Knox ,  Leonard A. Zheleznyak

发明人： Wayne H. Knox ,  Leonard A. Zheleznyak

IPC分类号： G02C7/04

CPC分类号： G02C7/049 ,  A61F9/00 ,  G02B5/1814 ,  G02B5/1847 ,  G02B7/002 ,  G02B27/0172 ,  G02C7/04 ,  G02C2202/06 ,  G02C2202/10 ,  G02C2202/20

摘要： An optical device for off-axis viewing includes a contact lens adapted for human eye wear. The contact lens includes a diffraction grating written into or on the contact lens. A peripheral light from a peripheral light source is diffracted by the diffraction grating so as to appear at about a same location as light from an ambient scene substantially in a direction of a central field of view. A wearer of the optical device for off-axis viewing sees simultaneously the peripheral light and the light from an ambient scene as superimposed at least in part over each other. A device-less method for correcting light direction from an ambient light source to a retina of a diseased or injured eye, and a remedial contact lens method for correcting light direction from an ambient light source to a retina of a diseased or injured eye are also described.