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12 条记录 (耗时 0.015 秒)

    MICROFLUID SYSTEM FOR THE ISOLATION OF BILOGICAL PARTICLES USING IMMUNOMAGNETIC SEPARATION
    6.
    发明申请
    MICROFLUID SYSTEM FOR THE ISOLATION OF BILOGICAL PARTICLES USING IMMUNOMAGNETIC SEPARATION 审中-公开
    使用免疫分离法分离白细胞的微流体系统

    公开(公告)号：US20090047297A1

    公开(公告)日：2009-02-19

    申请号：US11660778

    申请日：2005-08-22

    申请人： Jungtae Kim ,  Ute Steinfeld ,  Jorg Schuhmacher

    发明人： Jungtae Kim ,  Ute Steinfeld ,  Jorg Schuhmacher

    IPC分类号： A61K39/00 ,  B03C1/021

    CPC分类号： B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N33/54326 ,  G01N35/0098

    摘要： The present invention relates to a device and to a method for the isolation of biological particles. This device has a throughflow channel 5 and also a first and second magnetic field and also two inlet channels 1, 2 and two outlet channels 3, 4. The first magnetic field is disposed downstream of the inflow region of the inlet channels laterally of the throughflow channel 5, the second magnetic field 7 downstream of the first magnetic field 6 and on the oppositely situated side of the throughflow channel 5. The two magnetic fields can be produced also by a single magnet in a suitable arrangement.

    摘要翻译： 本发明涉及一种用于分离生物颗粒的装置和方法。 该装置具有通流通道5以及第一和第二磁场以及两个入口通道1,2和两个出口通道3,4。第一磁场设置在入口通道的流入区域的下游，该流入区域在通流侧面 通道5，第一磁场6下游的第二磁场7和通流通道5的相对位置的两个磁场。两个磁场也可以通过合适布置的单个磁体产生。

    Cell processor for use in the treatment of diseases
    7.
    发明申请
    Cell processor for use in the treatment of diseases 审中-公开
    细胞处理器用于治疗疾病

    公开(公告)号：US20070191819A1

    公开(公告)日：2007-08-16

    申请号：US10570004

    申请日：2004-08-23

    申请人： Ute Steinfeld ,  Hyeck-Hee Lee

    发明人： Ute Steinfeld ,  Hyeck-Hee Lee

    IPC分类号： A61K9/22

    CPC分类号： C12M47/04 ,  C12M35/08

    摘要： The present invention relates to a micromedical cell processor which modifies the cellular components of blood, especially cells of the body's natural immune defense, such that the cells, after their introduction into the body, exert a therapeutic function against cancerous diseases or against other diseases. The cell processor is implantable in the human or animal body and has a device for isolating cells, a device for fixing the cells, a device for introducing substances into the cells, and a device for determining the concentration of substances in the cells. The cell processor can also be used outside the body for loading the cells.

    摘要翻译： 本发明涉及一种微型细胞处理器，其改变血液的细胞成分，特别是身体的天然免疫防御细胞，使得细胞在其引入体内后，对癌症或其他疾病发挥治疗功能。 细胞处理器可植入人或动物体内，并具有用于分离细胞的装置，用于固定细胞的装置，用于将物质引入细胞的装置以及用于确定细胞中物质浓度的装置。 细胞处理器也可以在体外用于装载细胞。

    MOLECULARLY IMPRINTED POLYMER, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR THE SELECTIVE TREATMENT OF POORLY DEGRADABLE AND/OR TOXIC COMPOUNDS IN LIQUIDS
    9.
    发明申请
    MOLECULARLY IMPRINTED POLYMER, PROCESS FOR PRODUCTION THEREOF AND PROCESS FOR THE SELECTIVE TREATMENT OF POORLY DEGRADABLE AND/OR TOXIC COMPOUNDS IN LIQUIDS 审中-公开
    分子印迹聚合物，其生产方法和液体中不良可降解和/或毒性化合物的选择性处理方法

    公开(公告)号：US20100036188A1

    公开(公告)日：2010-02-11

    申请号：US12278717

    申请日：2007-02-20

    申请人： Ute Steinfeld ,  Barbara Palm

    发明人： Ute Steinfeld ,  Barbara Palm

    IPC分类号： A62D3/176 ,  A62D3/30 ,  A62D3/38 ,  A62D3/19 ,  A62D3/17 ,  C08J9/00

    CPC分类号： C02F1/285 ,  B01J20/268 ,  C02F1/32 ,  C02F1/725 ,  C02F2103/06 ,  C02F2305/10

    摘要： A molecularly imprinted polymer and production process therefor and a process for selective treatment of poorly degradable and/or toxic compounds in liquids using the molecularly imprinted polymers. Such polymers and processes are required for selective removal and/or degradation of biological, poorly degradable pollutants or toxic compounds, for example from wastewaters. Consequently, a molecularly imprinted polymer suitable for the selective treatment of at least one poorly degradable and/or toxic compound is provided having a polymeric network which is made up of monomers and has cavities of predetermined size, wherein the cavities are arranged at predetermined spacings and have specific binding sites and/or patterns for the poorly degradable and/or toxic compounds.

    摘要翻译： 分子印迹聚合物及其制备方法以及使用分子印迹聚合物选择性处理液体中难降解和/或有毒化合物的方法。 需要这样的聚合物和方法来选择性地去除和/或降解生物，难降解的污染物或有毒化合物，例如来自废水。 因此，提供了适用于选择性处理至少一种难降解和/或有毒化合物的分子印迹聚合物，其具有由单体组成且具有预定尺寸的空腔的聚合物网络，其中空腔以预定间隔排列， 对于难降解和/或毒性化合物具有特异性结合位点和/或图案。

    CELL MODIFICATION METHOD AND CELL MODIFICATION DEVICE
    10.
    发明申请
    CELL MODIFICATION METHOD AND CELL MODIFICATION DEVICE 审中-公开
    细胞修饰方法和细胞修饰装置

    公开(公告)号：US20090263899A1

    公开(公告)日：2009-10-22

    申请号：US12371082

    申请日：2009-02-13

    申请人： Ute STEINFELD ,  Hyeck Hee LEE

    发明人： Ute STEINFELD ,  Hyeck Hee LEE

    IPC分类号： C12N15/87 ,  C12N5/08 ,  C12N5/06 ,  C12M1/00

    CPC分类号： C12N5/0634 ,  A61K47/6901 ,  A61K2035/124

    摘要： The present invention relates to a cell modification method for modifying human or mammal immune cells, especially effector cells outside the human or mammal body, wherein in a first step at least one encapsulated substance, preferably an active pharmaceutical ingredient, is introduced in and/or arranged on isolated human or mammal immune cells and wherein in a second step prior to or after the introduction of said at least one substance the cytotoxic effector function of the isolated immune cells is enhanced. The present invention also relates to a correspondingly modified human or mammal immune cell and to a cell modification device.

    摘要翻译： 本发明涉及用于修饰人或哺乳动物免疫细胞，特别是人或哺乳动物身体外的效应细胞的细胞修饰方法，其中在第一步骤中，将至少一种包封物质，优选活性药物成分引入和/或 排列在分离的人或哺乳动物免疫细胞上，并且其中在引入所述至少一种物质之前或之后的第二步骤中，提高了分离的免疫细胞的细胞毒性效应子功能。 本发明还涉及相应修饰的人或哺乳动物免疫细胞和细胞修饰装置。