公开(公告)号：US20250042854A1

公开(公告)日：2025-02-06

申请号：US18710330

申请日：2022-11-15

Applicant: Ecole Nationale Supérieure de Chimie de Rennes ,  Institut National des Sciences Appliquées ,  Universite de Rennes ,  University of California, San Diego ,  Centre National de la Recherche Scientifique

Inventor： Marc MAUDUIT ,  Jennifer MORVAN ,  Jakub TALCIK ,  Rodolphe JAZZAR ,  Guy BERTRAND ,  Mohand-Ameziane MELAIMI ,  Melinda Rachel SERRATO

IPC: C07D209/56 ,  B01J31/22 ,  C07D209/96 ,  C07F7/08 ,  C07F7/18 ,  C07F15/00

Abstract: The present invention relates to an iminium salt having the following formula (I) and also to a ruthenium complex having the following formula (II): as well as the use of said ruthenium complex as catalyst, in particular in olefin metathesis.

公开(公告)号：US20240425623A1

公开(公告)日：2024-12-26

申请号：US18702930

申请日：2022-11-30

Applicant: TOTALENERGIES ONETECH BELGIUM ,  UNIVERSITE DE RENNES ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Kaitie GIFFIN ,  Jean-François CARPENTIER ,  Evgueni KIRILLOV ,  Alexandre WELLE ,  Virginie CIRRIEZ

IPC: C08F10/02

Abstract: The present invention relates to a catalyst composition comprising: catalyst component A comprising the meso form of a bridged metallocene compound with two indenyl groups, each indenyl being independently substituted with one or more substituents, wherein at least one of the substituents is on position 3 and/or 5 of each indenyl, and wherein at least one of the substituents is an aryl or heteroaryl; wherein the meso/rac ratio of the meso form of the bridged metallocene compound of catalyst component A is 95:5 or greater, as determined using 1H NMR; preferably wherein the aryl or heteroaryl substituent is on the 3-position of each indenyl; catalyst component B comprising a bridged metallocene compound with two indenyl groups, each indenyl being independently substituted with one or more substituents, wherein at least one of the substituents is an unsubstituted or substituted aryl or heteroaryl; and wherein the unsubstituted or substituted aryl or heteroaryl is not on position 3 and/or 5 of the indenyl; and an optional activator; an optional support; and an optional co-catalyst. The present invention also relates to a polymerization process using said composition. The invention further relates to olefin polymers at least partially catalyzed by said catalyst composition and articles comprising said olefin polymers.

公开(公告)号：US11905253B2

公开(公告)日：2024-02-20

申请号：US17049680

申请日：2019-04-19

Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  UNIVERSITE DE RENNES 1 ,  CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX ,  INSTITUT BERGONIE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) ,  UNIVERSITE DE BORDEAUX

Inventor： Pierre Vacher ,  Patrick Legembre ,  Mickael Jean ,  Patrick Blanco ,  Pierre Van De Weghe

IPC: C07D233/64 ,  A61P37/00 ,  A61K45/06

CPC classification number: C07D233/64 ,  A61K45/06 ,  A61P37/00

Abstract: The present invention relates the field of reducing CD95-mediated cell motility in a subject, in particular for their use in the reduction of CD-95 mediated cancer cell motility, the reduction of CD95-mediated lymphocyte motility and/or B cell maturation, or the treatment of B-cell tumors, in a subject. The inventors identified a novel family of compounds having the ability to disrupt CD95/PLCγ1 interaction and to neutralize the CD95-mediated calcium signaling pathway and cell migration in human peripheral blood lymphocytes (PBLs) and Th17 cells. Thus, the present invention relates to compounds of formula (A) as defined in the present text, to a pharmaceutical composition comprising said compounds in a pharmaceutically acceptable medium and to the use of these compounds and compositions as medicament, in particular for their use in the reduction or treatment of the above-mentioned pathologies, and in particular in the treatment of cancers and autoimmune inflammatory disease such as systemic lupus erythematosus, inflammatory condition and Th17-mediated disease.

公开(公告)号：US20230395989A1

公开(公告)日：2023-12-07

申请号：US18249893

申请日：2021-10-21

Applicant: NAVAL GROUP ,  UNIVERSITE DE RENNES ,  SERIBASE Industrie ,  Centre national de la recherche scientifique

Inventor： Mohamed HIMDI ,  Raimi BEN DEWAN ,  Xavier CASTEL ,  Patrick CALDAMONE ,  Thierry LEVAVASSEUR ,  Frédéric GOURMELEN ,  Patrick PARNEIX

IPC: H01Q17/00

CPC classification number: H01Q17/008 ,  H01Q17/007

Abstract: Disclosed is an absorbent structure which is a honeycomb structure extending between two end faces and which includes tubular cells, each cell having walls delimiting the cell, the walls extending between the two end faces, the walls being formed from a dielectric material, at least one cell having at least one strip of electrically conductive coating arranged in at least one wall or over a surface of at least one wall, the honeycomb structure being characterized by parameters chosen so that the absorbent structure provides an attenuation of at least 10 dB for each incident wave in a frequency range having a frequency spread greater than or equal to 15 GHz.

公开(公告)号：US11616290B2

公开(公告)日：2023-03-28

申请号：US17571326

申请日：2022-01-07

Applicant: BODYCAP ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  UNIVERSITE DE RENNES 1

Inventor： Denys Nikolayev ,  Maxim Zhadobov ,  Ronan Sauleau

IPC: H01Q1/38 ,  H01Q1/27 ,  H01Q5/357 ,  A61B5/07 ,  H01Q1/48 ,  H01Q21/28 ,  H01Q21/30

Abstract: Disclosed is a radio antenna comprising a substrate of dielectric material; a ground plane of electrically conductive material on a first face of the substrate; a resonator for converting an incident electrical signal into an electromagnetic wave and for resonating at at least two different resonant frequencies. The resonator comprises at least three elements, each in the form of strips of conductive material and arranged on a second face of the substrate opposite the first face. A second element is electrically connected to the ground plane by means of a via passing through the substrate at a first end of the corresponding strip, forms an extension of the first element, and is electrically connected directly to the first element at a second end of said strip which is opposite the first end.

公开(公告)号：US20230068095A1

公开(公告)日：2023-03-02

申请号：US17787965

申请日：2020-12-11

Applicant: DEMETA ,  UNIVERSITE DE RENNES 1

Inventor： IULIANA MARIA COTA ,  FRÉDÉRIC CAIJO ,  CHRISTOPHE DARCEL ,  VINCENT ESCANDE

IPC: C07C409/02 ,  B01J23/00

Abstract: The present invention relates to a process for preparing hydroperoxy alcohols using hydrogen peroxide as an oxidant in a solvent selected from water-soluble carboxylic acids, in the presence of a metallic mixed oxide heterogeneous catalyst. It also pertains to the use of this catalyst in the synthesis of hydroperoxy alcohols.

公开(公告)号：US11512050B2

公开(公告)日：2022-11-29

申请号：US17432504

申请日：2020-02-20

Applicant: DEMETA ,  UNIVERSITE DE RENNES 1

Inventor： Corentin Bordier ,  Vincent Escande ,  Frédéric Caijo ,  Christophe Darcel

IPC: C07C407/00

Abstract: The present invention relates to a process for synthesizing hydroperoxy alcohols by perhydrolysis of epoxides, using an aqueous solution of hydrogen peroxide, in the presence of a catalyst consisting of phosphotungstic acid.

公开(公告)号：US11484272B2

公开(公告)日：2022-11-01

申请号：US15765196

申请日：2016-09-30

Applicant: SORIN CRM SAS ,  INSERM—INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE ,  UNIVERSITE DE RENNES 1

Inventor： Jean-Luc Bonnet ,  Thomas Herrmann ,  Christine Henry ,  Alfredo Hernandez ,  Guy Carrault

IPC: A61B5/00 ,  G16H40/40 ,  G06F1/3206 ,  G06F1/3287 ,  G06F1/329 ,  A61B5/07 ,  A61N1/37 ,  A61B5/24 ,  A61B5/316 ,  A61B5/333 ,  A61B5/352 ,  A61B5/363 ,  A61B5/364 ,  A61B5/389 ,  G16H50/20 ,  A61B5/0245 ,  A61B5/08 ,  A61B5/11 ,  A61B5/024

Abstract: The invention relates to an active implantable medical device comprising a processing unit able to be alternately operated during a predetermined period of activity and on standby during a standby period in a cyclical manner, and means for acquiring data relating to physiological and/or physical activity. The device also comprises means for calculating a frequency analysis of the data acquired, said calculating means being capable of successively perform part of the frequency analysis during periods of activity of the processing unit.

公开(公告)号：US20220314686A1

公开(公告)日：2022-10-06

申请号：US17751079

申请日：2022-05-23

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - ,  UNIVERSITE DE RENNES 1

Inventor： Maxime HARNOIS ,  Jacques EMMANUEL ,  Brice LE BORGNE

IPC: B44C1/175 ,  B41F7/02

Abstract: Solvent transfer printing method for applying a pattern (1) made of a non-soluble material and non-dispersible (10) on the surface of an object (2), the method comprising the following steps: m1/forming a pattern (1) on a surface of a solvent-soluble substrate (3), m2/depositing the solvent-soluble substrate (3) on the surface of a solvent bath (5), on the side of the substrate opposed to the side on which the pattern is applied, in order to dissolve partially the substrate (3), m3/dipping the object (2) in the bath (5), so that the surface of the object (2) comes into contact with the pattern (1), m4/getting the object (2), on which the pattern (1) is applied, out of the bath (5), m5/drying the object (2).

公开(公告)号：US20220153786A1

公开(公告)日：2022-05-19

申请号：US17432026

申请日：2020-02-20

Applicant: UNIVERSITE DE RENNES 1 ,  Centre national de la recherche scientifique ,  UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL UFRGS

Inventor： Rafael GOMES VON BOROWSKI ,  Aline RIGON ZIMMER ,  Simone Cristina BAGGIO GNOATTO ,  Alexandre José MACEDO ,  Muriel PRIMON DE BARROS ,  Karine RIGON ZIMMER ,  Reynald GILLET ,  Grace GOSMANN

IPC: C07K14/415 ,  A61L27/54 ,  A61L29/16 ,  C07K7/08

Abstract: The present invention relates to the use of a peptide to prevent biofilm formation by microorganisms on a surface, wherein said peptide is (i) a peptide consisting of 6 to 37 consecutive amino acids from a peptide of sequence SEQ ID NO: 1, (ii) a peptide of sequence SEQ ID NO: 4, or (iii) a peptidomimetic of (i) or (ii).