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公开(公告)号：US20170281859A1
公开(公告)日：2017-10-05
申请号：US15625563
申请日：2017-06-16
发明人： Ryan M. Agard , Ian B. Hanson , Nicholas J. Ciccarelli , Sean M. O'Connor , Kevin Bokelman , Paul F. Bente, IV , John C. Love , Christopher Edward Hatch
CPC分类号： A61M5/14216 , A61M5/14248 , A61M5/1454 , A61M5/14566 , A61M5/172 , A61M2005/14252 , A61M2005/2474 , A61M2205/3317 , A61M2205/3379 , A61M2205/50 , A61M2205/58 , A61M2205/82
摘要： A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.
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公开(公告)号：US09707335B2
公开(公告)日：2017-07-18
申请号：US14230784
申请日：2014-03-31
发明人： Ryan M. Agard , Ian B. Hanson , Nicholas J. Ciccarelli , Sean M. O'Connor , Kevin Bokelman , Paul F. Bente, IV , John C. Love , Christopher Edward Hatch
CPC分类号： A61M5/14216 , A61M5/14248 , A61M5/1454 , A61M5/14566 , A61M5/172 , A61M2005/14252 , A61M2005/2474 , A61M2205/3317 , A61M2205/3379 , A61M2205/50 , A61M2205/58 , A61M2205/82
摘要： A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing, the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.
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公开(公告)号：US20170157328A1
公开(公告)日：2017-06-08
申请号：US15426503
申请日：2017-02-07
发明人： Lance W. Wetzel , Gautam N. Shetty , Lou Castagna
摘要： Mixing syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject.
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公开(公告)号：US09636466B2
公开(公告)日：2017-05-02
申请号：US13688386
申请日：2012-11-29
发明人： Craig Stephen Thorley , Joseph Hermes Kaal , Chris Rafferty , Richard Sokolov , Ernesto Hueso , Huw Wallis , Steve Chi Truong
CPC分类号： A61M5/3232 , A61M5/31511 , A61M5/3202 , A61M5/3234 , A61M5/345 , A61M2005/3103 , A61M2005/323 , A61M2005/3231 , A61M2005/3238 , A61M2005/5073 , A61M2205/581 , A61M2205/582 , Y10T29/49826
摘要： A retractable syringe, plunger and releasable needle assembly including a retractable needle, a needle seal, a retaining member and an ejector member. The retaining member has a mating surface for mounting to a complementary mating surface of an interior wall of a syringe barrel. The plunger comprises a plunger outer, a plunger rod frangibly connected to a controlling member, a spring and a unitary plunger seal capable of engaging the retractable needle, wherein the plunger rod, plunger outer and the controlling member co-operate to releasably maintain the spring in an initially compressed state. After delivery of fluid contents of the syringe, the plunger forces the ejector member to release the retractable needle from the retaining member. Decompression of the spring at the end of depression of the plunger facilitates retraction of the retractable needle when engaged with the unitary plunger seal.
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公开(公告)号：US09597454B2
公开(公告)日：2017-03-21
申请号：US14333442
申请日：2014-07-16
发明人： Lance W. Wetzel , Gautam N. Shetty , Lou Castagna
CPC分类号： A61M5/2448 , A61M5/31525 , A61M5/31533 , A61M5/31535 , A61M5/31578 , A61M5/31591 , A61M5/31596 , A61M5/322 , A61M5/3234 , A61M2005/2451 , A61M2005/3128
摘要： Mixing syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject.
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公开(公告)号：US20170065775A1
公开(公告)日：2017-03-09
申请号：US15354712
申请日：2016-11-17
CPC分类号： A61M5/5086 , A61M5/3134 , A61M5/3221 , A61M5/3232 , A61M5/3234 , A61M5/345 , A61M5/347 , A61M2005/3104 , A61M2005/3106 , A61M2005/323 , A61M2005/3231 , A61M2005/3241
摘要： A connector mountable to a syringe barrel has a proximal barrel-engaging portion, a distal luer fitment portion, and a fluid aperture therethrough. The barrel-engaging portion of the connector includes an axial ledge configured to abut the axial distal edge of a glass syringe barrel. The connector facilitates mounting a luer assembly to the barrel. The luer assembly may be a tip cap having a complementary luer fitment for connection to the luer fitment portion of the connector. The luer assembly may be a luer needle assembly having a complementary luer fitment for connection to the luer fitment portion of the connector. The connector and syringe may further include an immobile, compressible needle seal. The needle seal is adjacent to or engageable with the barrel-engaging portion of the connector. The syringe may be configured with a plunger capable of engaging a retractable needle.
摘要翻译： 可连接到注射器筒的连接器具有近端针筒接合部分，远端鲁尔配件部分和穿过其中的流体孔。 连接器的筒体接合部分包括构造成邻接玻璃注射器筒的轴向远端边缘的轴向凸缘。 连接器便于将路厄组件安装到筒体上。 鲁尔组件可以是具有用于连接到连接器的鲁尔配件部分的互补鲁尔配件的尖端盖。 鲁尔组件可以是具有用于连接到连接器的鲁尔配件部分的互补鲁棒配件的路厄针组件。 连接器和注射器还可以包括不可移动的可压缩的针密封件。 针状密封件与连接器的筒形接合部分相邻或接合。 注射器可以配置有能够接合可缩回针的柱塞。
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公开(公告)号：US20160263329A1
公开(公告)日：2016-09-15
申请号：US15163458
申请日：2016-05-24
CPC分类号： A61M5/31526 , A61M5/28 , A61M5/31528 , A61M5/3157 , A61M5/31575 , A61M5/3158 , A61M5/31585 , A61M2005/3139 , A61M2005/3152 , A61M2205/581 , A61M2205/582 , Y10T29/49826
摘要： A dose control mechanism for a syringe includes an engaging screw thread arrangement between an exterior surface of a plunger and a longitudinally extending channel of a housing. The engaging screw thread arrangement includes at least one thread segment and a pitch guide including a variable pitch thread. At least a portion of the longitudinally extending channel of the housing including one of the pitch guide and the at least one thread segment, and the plunger includes the other of the pitch guide and the at least one thread segment. The plunger resides at least partially within the housing with the at least one thread segment engaged with the pitch guide. An accurate dose drug delivery syringe includes such a dose control mechanism, a barrel, a plunger seal, and a barrel adapter assembly having a barrel tip and a needle. The syringe may be a fill-at-time-of-use syringe, a pre-filled syringe, or a safety syringe having integrated needle retraction or needle sheathing safety features, or a combination thereof. Methods of assembly, manufacturing, and operation are similarly disclosed.
摘要翻译： 用于注射器的剂量控制机构包括在柱塞的外表面和壳体的纵向延伸通道之间的接合螺纹排列。 接合螺纹装置包括至少一个螺纹段和包括可变节距螺纹的桨距引导件。 所述壳体的纵向延伸通道的至少一部分包括所述俯仰引导件和所述至少一个螺纹段中的一个，并且所述柱塞包括所述俯仰引导件和所述至少一个螺纹段中的另一个。 柱塞至少部分地位于壳体内，其中至少一个螺纹段与桨距引导件接合。 精确剂量的药物输送注射器包括这样的剂量控制机构，筒体，柱塞密封件以及具有圆筒末端和针头的圆筒适配器组件。 注射器可以是使用时间充分的注射器，预填充注射器或具有集成针回缩或针头护套安全特征的安全注射器，或其组合。 类似地公开了组装，制造和操作的方法。
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公开(公告)号：US20160175541A1
公开(公告)日：2016-06-23
申请号：US15053871
申请日：2016-02-25
发明人： Craig Stephen Thorley , Joseph Hermes Kaal , Christopher Charles Rafferty , Ian Johnson , Eric Siu , Andrew Reade
CPC分类号： A61M5/3234 , A61M5/502 , A61M2005/3231 , A61M2005/3241 , A61M2005/5033 , A61M2202/30 , Y10T29/49826
摘要： A replaceable needle assembly is provided for a retractable, prefilled syringe comprising a barrel having a mounting member and a plunger, whereby the retractable needle can be replaced by a user without affecting the retraction mechanism. The replaceable needle assembly comprises a needle fitted to a retractable needle mount and a needle retainer. The needle mount is removably, screw-threadedly mountable to the mounting member of the barrel. The needle retainer comprises a plurality of fingers that releasably engage the retractable needle to thereby prevent inadvertent retraction of the retractable needle before engagement by the plunger. The plunger comprises a plunger seal comprising an outer member and an inner member that engages the needle for spring-driven retraction. At the end of retraction, a lock is formed between the plunger and barrel to prevent re-use of the syringe.
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公开(公告)号：USD723157S1
公开(公告)日：2015-02-24
申请号：US29455724
申请日：2013-05-23
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公开(公告)号：US20150025455A1
公开(公告)日：2015-01-22
申请号：US14333451
申请日：2014-07-16
发明人： Gautam N. Shetty , Lou Castagna
CPC分类号： A61M5/2448 , A61M5/31525 , A61M5/31533 , A61M5/31535 , A61M5/31578 , A61M5/31591 , A61M5/31596 , A61M5/322 , A61M5/3234 , A61M2005/2451 , A61M2005/3128
摘要： Mixing syringes including a valve mechanism are configured and configurable to enable one or more substances to be prefilled into the syringe. The valve mechanism may be an aspect of a distal seal assembly. Actuation of the valve mechanism permits opening of a fluid passage for the mixing of one or more substances, and the resulting mixed substance can be delivered by the syringe, for example, for administration of a pharmaceutical to a subject. The repetitive mixing of substances contained in a distal and proximal chamber is also provided, where the plunger rod is configured to releasably engage a locking mechanism to actuate the valve, and can axially displace the distal seal assembly while the fluid passage is open.
摘要翻译： 包括阀机构的混合注射器被配置和配置以使一种或多种物质能够预填充到注射器中。 阀机构可以是远端密封组件的一个方面。 阀机构的致动允许打开用于混合一种或多种物质的流体通道，并且所得到的混合物质可以通过注射器输送，例如用于向受试者施用药物。 还提供了包含在远端和近侧腔室中的物质的重复混合，其中柱塞杆构造成可释放地接合锁定机构以致动阀门，并且可以在流体通道打开时轴向移动远端密封组件。
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